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Maternal and paternal inflammatory disease can affect pregnancy outcomes

Data presented at the 2021 EULAR congress show women with rheumatoid arthritis (RA) are at increased risks of adverse pregnancy outcomes, especially pre-term birth and babies small for gestational age.

18 Jun 2021

Study analyzes uveitis risk after antirheumatic drug withdrawal in children with arthritis

Uveitis is an inflammation of the eye and is a common extra-articular manifestation associated with juvenile idiopathic arthritis (JIA). It can cause vision-threatening complications, and if left uncontrolled may even lead to blindness.

18 Jun 2021

Deep learning could transform the ability to accurately interpret HIV test results

Pioneering technology developed by UCL and Africa Health Research Institute researchers could transform the ability to accurately interpret HIV test results, particularly in low- and middle-income countries.

18 Jun 2021

Baseline use of DMARDs linked with COVID-19 severity in rheumatoid arthritis patients

Due to sample size limitations, previous studies of DMARD use and COVID-19 outcomes have combined several different rheumatic diseases and medications, and investigated a single outcome- for example, the risk of hospitalization.

18 Jun 2021

Could a fungus-derived compound reduce hyperinflammation in severe COVID-19?

New research from scientists at the University of Pennsylvania, USA, demonstrates that cyclosporine A (CSA), a calcineurin inhibitor that modulates cytokine production, may have potential antiviral properties against coronaviruses.

18 Jun 2021

Could horse-derived antibody therapy be effective against SARS-CoV-2 variants of concern?

A new study, released as a preprint on the bioRxiv* server, reveals the high neutralizing efficacy of hyperimmune horse serum against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This could prove, if validated, to be a more affordable yet potent therapeutic in reducing the morbidity and mortality caused by this virus.

18 Jun 2021

Convalescent plasma associated with better survival in blood cancer patients with COVID-19

Convalescent plasma therapy was associated with better survival in blood cancer patients hospitalized with COVID-19, especially in sicker patients. The findings by the COVID-19 and Cancer Consortium (CCC19) are newly published in the peer-reviewed journal JAMA Oncology.

18 Jun 2021

KIYATEC’s test results accurately predict treatment response in recurrent high-grade glioma patients

KIYATEC, Inc. announced today the publication of new peer-reviewed data that establishes clinically meaningful prediction of patient-specific responses to standard of care therapy, prior to treatment, in newly diagnosed glioblastoma (GBM) and other high-grade glioma (HGG) patients.

18 Jun 2021

Researchers design a smart device that delivers medications to prevent HIV transmission

Researchers have designed a device that delivers two medications that help stop HIV transmission.

18 Jun 2021

Nanodecoys made from human lung spheroid cells can neutralize SARS-CoV-2

Nanodecoys made from human lung spheroid cells (LSCs) can bind to and neutralize SARS-CoV-2, promoting viral clearance and reducing lung injury in a macaque model of COVID-19.

18 Jun 2021

Convalescent plasma can improve chances of survival among blood cancer patients with COVID-19

A large, retrospective, multicenter study involving Washington University School of Medicine in St. Louis indicates that convalescent plasma from recovered COVID-19 patients can dramatically improve likelihood of survival among blood cancer patients hospitalized with the virus.

18 Jun 2021

Study shows how epigenetic factors modulate the risk of type 1 diabetes

Genetics plays a major role in determining a person’s risk of developing type 1 diabetes, but environmental and lifestyle factors are also important. In an article recently published in Chinese Medical Journal, a team of researchers explore the interplay of genetic and environmental factors by summarizing the literature on type 1 diabetes and epigenetics—the study of how gene expression patterns can be modified.

18 Jun 2021

Which vitamins and minerals help with COVID?

A study published in the journal Inflammopharmacology reviewed recent data related to the role of vitamins and minerals in treating COVID-19 patients. The primary goal of the review is to highlight the possible therapeutic role of vitamins A, B, C, D, E and K, and micronutrients as immunity boosters in COVID-19 patients.

18 Jun 2021

Combination of anti-HER2 breast cancer therapy and checkpoint inhibitor provides no benefit

Adding an immune checkpoint inhibitor to anti-HER2 treatment in breast cancer does not improve pathological complete response (pCR), according to the primary analysis of the IMpassion050 trial presented today during the ESMO Virtual Plenary.

18 Jun 2021

New methods may lead to optimal treatment for lung cancer

Today as they did 100 years ago, doctors diagnose cancer by taking tissue samples from patients, which they usually fix in formalin for microscopic examination.

18 Jun 2021

New guidance provides valuable direction in the clinical use of HR-pQCT imaging

In recent years, significant progress has been made towards the use of high-resolution peripheral computed tomography (HR-pQCT) imaging in research, and new potential for applications in the clinic have emerged, particularly with the advent of second generation devices.

18 Jun 2021

Adding immune oncology drug to chemotherapy improves response in subset of breast cancer patients

In a new study by researchers at Yale Cancer Center, combining the immunotherapy drug durvalumab and PARP-inhibitor olaparib with chemotherapy improved response to treatment for women with high-risk, HER2-negative breast cancer, including a subset of estrogen receptor positive cancers.

18 Jun 2021

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails.

18 Jun 2021

Foresight Diagnostics to demonstrate utility of PhasED-Seq technology at ICML meeting

Foresight Diagnostics, the emerging leader in blood-based lymphoma disease monitoring, announced today that clinical performance of its minimal residual disease (MRD) detection platform in diffuse large B-cell lymphoma (DLBCL) will be presented at the 16th International Conference on Malignant Lymphoma (ICML) on June 18-22, 2021.

18 Jun 2021

Proven treatment for psychosis has been recognized as standard of care

Most people with a serious mental illness like schizophrenia will not obtain adequate care. Many end up in correctional facilities on medication or become homeless.

18 Jun 2021

Therapy News and Research

Maternal and paternal inflammatory disease can affect pregnancy outcomes

Study analyzes uveitis risk after antirheumatic drug withdrawal in children with arthritis

Deep learning could transform the ability to accurately interpret HIV test results

Baseline use of DMARDs linked with COVID-19 severity in rheumatoid arthritis patients

Could a fungus-derived compound reduce hyperinflammation in severe COVID-19?

Could horse-derived antibody therapy be effective against SARS-CoV-2 variants of concern?

Convalescent plasma associated with better survival in blood cancer patients with COVID-19

KIYATEC’s test results accurately predict treatment response in recurrent high-grade glioma patients

Researchers design a smart device that delivers medications to prevent HIV transmission

Nanodecoys made from human lung spheroid cells can neutralize SARS-CoV-2

Convalescent plasma can improve chances of survival among blood cancer patients with COVID-19

Study shows how epigenetic factors modulate the risk of type 1 diabetes

Which vitamins and minerals help with COVID?

Combination of anti-HER2 breast cancer therapy and checkpoint inhibitor provides no benefit

New methods may lead to optimal treatment for lung cancer

New guidance provides valuable direction in the clinical use of HR-pQCT imaging

Adding immune oncology drug to chemotherapy improves response in subset of breast cancer patients

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

Foresight Diagnostics to demonstrate utility of PhasED-Seq technology at ICML meeting

Proven treatment for psychosis has been recognized as standard of care

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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