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TSRI scientists develop new process to synthesize naturally occurring compound phorbol

In a landmark feat of chemical synthesis, scientists at The Scripps Research Institute have developed a 19-step process for making the naturally occurring compound phorbol in the laboratory, in quantities that are useful for pharmaceutical research.

24 Mar 2016

Researchers develop versatile building blocks that could be useful in pharmaceutical research

Researchers in the Doyle lab at Princeton have developed a direct cross-coupling reaction to produce nitrogen-containing compounds called 1,2-dihydropyridines, versatile building blocks that are highly useful in pharmaceutical research.

24 Mar 2016

Virus-generated DNA lurking between human genes, show research

Think your DNA is all human? Think again. And a new discovery suggests it's even less human than scientists previously thought.

24 Mar 2016

UAM implements family-centered care model to provide better patient outcomes

Family presence when a child is undergoing tracheal intubation in a pediatric intensive care unit (PICU) can safely be implemented as part of a family-centered care model, reported a research team led by a University of Arkansas for Medical Sciences professor in the March 7 issue of JAMA Pediatrics.

24 Mar 2016

Omega-6 fatty acids can reduce risk of type 2 diabetes

A new study from the University of Eastern Finland shows that high serum omega-6 polyunsaturated fatty acid concentrations are linked to a significantly reduced risk of type 2 diabetes. The findings were published in the American Journal of Clinical Nutrition.

24 Mar 2016

New project aims to prevent complications from drug usage

If a patient is ill and takes drugs for that illness, these drugs often lead to further illnesses and complications. This affects millions of people throughout the world.

24 Mar 2016

Neurons in hypothalamus help maintain blood glucose levels, study finds

To learn what different cells do, scientists switch them on and off and observe what the effects are. There are many methods that do this, but they all have problems: too invasive, or too slow, or not precise enough. Now, a new method to control the activity of neurons in mice, devised by scientists at Rockefeller University and Rensselaer Polytechnic Institute, avoids these downfalls by using magnetic forces to remotely control the flow of ions into specifically targeted cells.

24 Mar 2016

Tooth loss leads to cognitive impairment, shows study

The International and American Associations for Dental Research have published an article titled "Tooth Loss Increases the Risk of Diminished Cognitive Function: A Systematic Review and Meta-analysis" in the OnlineFirst portion of the JDR Clinical & Translational Research. In it, Cerutti-Kopplin et al systematically assessed the association between oral health and cognitive function in adult populations.

24 Mar 2016

MALDI tissue imaging spots early renal lipid changes in acute kidney injury

University of Alabama at Birmingham researchers have made a microscopic snapshot of the early renal lipid changes in acute kidney injury, using the laser-scanning method called MALDI tissue imaging to localize the changes.

24 Mar 2016

Tough men more likely to ignore medical problems

Men are less likely than women to go to the doctor, more likely to choose a male doctor when they do go, but less likely to be honest with that doctor about their symptoms, Rutgers psychologists have found. The researchers believe this may contribute to men's dying earlier than women.

24 Mar 2016

Researchers explore role of social media in promoting mental health, wellbeing in children

University of Leicester researchers to identify the benefits and challenges of promoting mental health through social media

24 Mar 2016

Research shows women have more risk factors for heart disease

Despite messages to the contrary, most women being seen by a doctor for the first time with suspected heart disease actually experience the same classic symptoms as men, notably chest pain and shortness of breath, according to a study led by the Duke Clinical Research Institute.

24 Mar 2016

Kids with minor head injuries may not require hospitalization, study suggests

Challenging the longstanding practice of keeping all children with head injuries in the hospital overnight, new research from Ann & Robert H. Lurie Children's Hospital suggests that patients with simple skull fractures can be sent home safely if they have no evidence of brain injury and no neurological symptoms.

24 Mar 2016

Reducing sitting time to less than three hours per day could increase life expectancy

Investigators Estimate Limiting Sitting to Less than Three Hours Per Day Could Increase Life Expectancy, According to a New Study Published in the American Journal of Preventive Medicine

24 Mar 2016

Increased use of PNBs in hip and knee arthroplasty could improve medical outcomes

The use of peripheral nerve blocks (PNBs) is associated with better medical and economic outcomes in patients receiving hip and knee replacement, according to research being presented at the 41st Annual Regional Anesthesiology and Acute Pain Medicine Meeting later this month.

24 Mar 2016

New research shows bacterial biofilms are stronger than single-celled bacteria

New research from the University of Copenhagen reveals that bacteria which agglutinate before entering the body are far more resistant than single-celled bacteria. This may be the cause of chronic infections.

24 Mar 2016

Engineered vaginal Lactobacilli could reduce heterosexual HIV-1 transmission in women

A normal, predominant bacterial species of the healthy vaginal microbiota can be engineered for potential use as a novel protective agent against HIV-1 transmission in women, according to a new publication from scientists at Osel, Inc. and their collaborators.

24 Mar 2016

Innovative ultrasound method can help determine risk of strokes, heart attacks

Researchers at Lund University in Sweden have discovered a new and more accurate way to distinguish between harmful and harmless plaque in the blood vessels by using ultrasound. This can help healthcare providers determine the risk of strokes and heart attacks - which means avoiding unnecessary surgery for many patients.

24 Mar 2016

Children with cardiomyopathy may benefit from family-linked treatment

A newly published national study by the Children's Hospital of Michigan and Wayne State University School of Medicine researchers shows that "parental impact and family functioning" become increasingly abnormal when children with cardiomyopathy-related chronic heart disease are more severely ill than children less affected by the disease.

24 Mar 2016

NIHR research program aims to increase safety, well-being of victims of DVA

Researchers at the University of Bristol have received more than £2.5 million from the National Institute for Health Research to carry out research that aims to increase the safety and well-being of victims of domestic violence and abuse (DVA).

24 Mar 2016

Research News and Research

TSRI scientists develop new process to synthesize naturally occurring compound phorbol

Researchers develop versatile building blocks that could be useful in pharmaceutical research

Virus-generated DNA lurking between human genes, show research

UAM implements family-centered care model to provide better patient outcomes

Omega-6 fatty acids can reduce risk of type 2 diabetes

New project aims to prevent complications from drug usage

Neurons in hypothalamus help maintain blood glucose levels, study finds

Tooth loss leads to cognitive impairment, shows study

MALDI tissue imaging spots early renal lipid changes in acute kidney injury

Tough men more likely to ignore medical problems

Researchers explore role of social media in promoting mental health, wellbeing in children

Research shows women have more risk factors for heart disease

Kids with minor head injuries may not require hospitalization, study suggests

Reducing sitting time to less than three hours per day could increase life expectancy

Increased use of PNBs in hip and knee arthroplasty could improve medical outcomes

New research shows bacterial biofilms are stronger than single-celled bacteria

Engineered vaginal Lactobacilli could reduce heterosexual HIV-1 transmission in women

Innovative ultrasound method can help determine risk of strokes, heart attacks

Children with cardiomyopathy may benefit from family-linked treatment

NIHR research program aims to increase safety, well-being of victims of DVA

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