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Ancient retrovirus may be responsible for aggressive brain cancers

The median length of survival after diagnosis of glioblastoma is 14 months, but some of these brain tumors are more aggressive and resistant to treatment than others, and a new study from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests reactivation of an ancient retrovirus may be at least partly to blame.

3 Jul 2023

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Formononetin (FNT), an isoflavonoid present in beer, was investigated for its effects on chondrocytes, the cells responsible for joint health. While low levels of FNT showed no harm and reduced inflammation, excessive exposure promoted catabolic responses, shedding light on the relationship between beer consumption and osteoarthritis risk.

3 Jul 2023

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology.

3 Jul 2023

Researchers discover a molecular switch that regulates lipid metabolism in cells

Our body's fat metabolism plays a vital role in energy production in our body. A research team at the University of Basel, Switzerland, has discovered a molecular switch that regulates lipid metabolism in our cells.

3 Jul 2023

Korean researchers develop hydrogel that could revolutionize treatment for female infertility

The Health Insurance Review & Assessment Service revealed that over the last year, more than 370,000 Koreans sought medical help for infertility or difficulties in conceiving.

3 Jul 2023

Research reveals how cells carry out the controlled release of mucins and insulin

Researchers from the Centre for Genomic Regulation (CRG) in Barcelona have published a study in the journal Nature Communications that reveals how cells carry out the controlled release of mucins and insulin, two crucial proteins for human health.

3 Jul 2023

Cell therapy using genome-edited iPS cells could be a new treatment for Fabry disease

Induced pluripotent stem (iPS) cells have a great impact on biology and medicine, and they are expected to improve regenerative medicine.

3 Jul 2023

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia.

3 Jul 2023

SPG-15: A Mother's Fight for a Gene Therapy Cure, Maddi's Story

News Medical spoke to the CEO and founder of the Maddi Foundation to gain a patient perspective on how important research in gene therapy is.

3 Jul 2023

Precision protection: antibody testing offers insights into predicting SARS-CoV-2 infection risk in immunocompromised patients

Researchers used antibody testing to predict the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

3 Jul 2023

Insights gained from genetically modified pig heart transplantation

Researchers described a genetically engineered pig cardiac xenotransplantation in a 57-year-old male patient.

3 Jul 2023

Cutting-edge research: machine learning identifies early predictors of type 1 diabetes

Scientists utilized plasma protein proteomics to identify proteins associated with the onset of type 1 diabetes.

3 Jul 2023

New technology to capture and release cfDNA on nanowire surfaces from urine

A group led by researchers at Nagoya University in Japan has developed a technology to capture and release cell-free DNA (cfDNA) on nanowire surfaces from urine.

3 Jul 2023

New COVID-19 mRNA vaccine is safe and highly immunogenic as a heterologous booster: Study

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in more than 600 million confirmed cases and 6.5 million deaths worldwide.

3 Jul 2023

COVID-19 severity linked to autoantibodies against blood clotting protein

Study investigates the occurrence of ADAMTS13 antibodies in COVID-19 patients and their association with disease severity and lower ADAMTS13 activity. The findings suggest the need to include ADAMTS13 antibodies in diagnosing and managing SARS-CoV-2 infections.

2 Jul 2023

How does space affect the immune system of astronauts?

Research explores the effects of microgravity and radiation on the immune system in space conditions. It emphasizes the need to understand these effects for future long-duration space missions and highlights knowledge gaps for further investigation.

2 Jul 2023

Spanish researchers develop new immunotherapy combination for liver cancer

Spanish researchers at Cima University of Navarra have developed a new immunotherapy combination that improves efficacy in animal models of hepatocellular carcinoma. This is a proof of concept that lays the foundations for the application of this treatment in patients with the most common liver cancer.

1 Jul 2023

Newly identified immune checkpoint receptor could lead to treatments for diseases

Researchers from the University of Colorado Anschutz Medical Campus have identified a potential new immune checkpoint receptor that could lead to treatments for diseases such as lung and bowel cancer and autoimmune conditions including IBD.

30 Jun 2023

Study finds age-dependent genetic mutations linked to treatment-resistant breast cancer

A study led by researchers at Sanford Burnham Prebys has found that in young women, certain genetic mutations are associated with treatment-resistant breast cancer.

30 Jun 2023

High-res insights into key bacterial enzyme could lead to development of new antibiotics

A team of scientists from around the globe, including those from Trinity College Dublin, has gained high-res structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it and thus suppress disease-causing bacteria.

30 Jun 2023

Cell News and Research

Ancient retrovirus may be responsible for aggressive brain cancers

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Researchers discover a molecular switch that regulates lipid metabolism in cells

Korean researchers develop hydrogel that could revolutionize treatment for female infertility

Research reveals how cells carry out the controlled release of mucins and insulin

Cell therapy using genome-edited iPS cells could be a new treatment for Fabry disease

Base editing shows promise for treating sickle cell disease and beta thalassemia

SPG-15: A Mother's Fight for a Gene Therapy Cure, Maddi's Story

Precision protection: antibody testing offers insights into predicting SARS-CoV-2 infection risk in immunocompromised patients

Insights gained from genetically modified pig heart transplantation

Cutting-edge research: machine learning identifies early predictors of type 1 diabetes

New technology to capture and release cfDNA on nanowire surfaces from urine

New COVID-19 mRNA vaccine is safe and highly immunogenic as a heterologous booster: Study

COVID-19 severity linked to autoantibodies against blood clotting protein

How does space affect the immune system of astronauts?

Spanish researchers develop new immunotherapy combination for liver cancer

Newly identified immune checkpoint receptor could lead to treatments for diseases

Study finds age-dependent genetic mutations linked to treatment-resistant breast cancer

High-res insights into key bacterial enzyme could lead to development of new antibiotics

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