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Study finds E2F5 transcription factor commonly overexpressed in primary human HCC

E2F5 is a member of the E2F transcription factor family, and plays a key role in cell growth and proliferation. Overexpression of E2F5 has been reported in various human cancers, but not in liver cancer, and its biological implication is largely unknown. It is not known whether E2F5 plays a tumor suppressor role or an oncogenic role.

1 Feb 2011

Health Canada approves Microsulis Medical's Accu2i percutaneous microwave tissue ablation system

Microsulis Medical Limited, the leading company in microwave technology for medical devices, today announced that it has received approval from Health Canada for the Acculis Accu2i percutaneous microwave tissue ablation system for the coagulation of soft tissue during surgical procedures.

1 Feb 2011

Research sheds new light on venous thromboembolism following liver resections

Patients undergoing liver surgery have long been considered to be at low risk of venous thromboembolism. However, pulmonary embolism has recently emerged as an increasingly frequent and potentially fatal complication following liver resections.

1 Feb 2011

New research finding shows strong relationship between gut bacteria and fatty liver

The more we learn about biology, the closer we get to being able to treat disease - and the more complicated our understanding of disease itself becomes. A new research finding showing a strong relationship between complex microbial ecologies in human intestines and the common but serious medical condition known as fatty liver illustrates this paradox.

1 Feb 2011

FDA approves Boston Scientific's Renegade HI-FLO Fathom Pre-Loaded System

Boston Scientific Corporation today announced that the U.S. Food and Drug Administration has approved its Renegade HI-FLO Fathom Pre-Loaded System for selective access and delivery of diagnostic, embolic and therapeutic materials into the peripheral vasculature.

1 Feb 2011

MRI T2 can determine iron overload in beta-thalassemic patients

Iron overload is a common and serious problem in thalassemic major patients. As iron accumulation is toxic in the body's tissues, accurate estimation of iron stores is of great importance in these patients to prevent iron overload by an appropriate iron chelating therapy.

1 Feb 2011

GATTEX Phase 3 pivotal study reaches primary efficacy endpoint of reducing PN in patients with SBS

NPS Pharmaceuticals, a specialty pharmaceutical company developing innovative therapeutics for rare gastrointestinal and endocrine disorders, today announced that its Phase 3 pivotal study of GATTEX met the primary efficacy endpoint of reducing parenteral nutrition dependence in patients with adult short bowel syndrome.

31 Jan 2011

EU grants 3.3 million to AMP for gene therapy development against AIP

Amsterdam Molecular Therapeutics, a leader in the field of human gene therapy, announced today that the European Union has finalized a EUR 3.3 million grant to the AIPGENE consortium, of which AMT is a member, for the development of a gene therapy product for Acute Intermittent Porphyria.

31 Jan 2011

New research shows CEUS can improve diagnosis of variety of medical conditions in children

New research released here Thursday shows that "contrast-enhanced ultrasound" can safely improve the diagnosis of a variety of medical conditions in children - without exposing them to ionizing radiation.

29 Jan 2011

Budget woes lead states to seek ways to ease Medicaid's requirements

While The Hill reports that CMS administrator Donald Berwick says his agency is trying to help states find solutions, National Journal notes that mounting budgetary pressure has put the program in "dire fiscal straits."

29 Jan 2011

EHSI examines business plans and product lines of OceanBASIS

Emerging Healthcare Solutions, Inc. is examining the business plans and product lines of German biotech firm OceanBASIS as part of the company's due diligence towards a potential profit sharing agreement.

28 Jan 2011

HIV causes specific subset of CD4+ T-cells to age rapidly: Study

In the early years of the AIDS epidemic, being infected with the virus that causes the disease was considered a virtual death sentence. But with the development of antiretroviral therapy, many with HIV are now living much longer. In fact, it is estimated that by 2015, about half of all HIV-positive individuals will be older than 50.

28 Jan 2011

Provectus announces completion of PV-10 Phase 1 trial in patients with liver cancer

Provectus Pharmaceuticals, a development-stage oncology and dermatology biopharmaceutical company, has completed patient accrual and treatment of all subjects in its Phase 1 clinical trial of PV-10 for liver cancer.

27 Jan 2011

Fibroblasts help 'recruit' immune cells for tumor growth

The most common connective tissue cell in animals is the fibroblast, which plays an important role in healing wounds. But Dr. Neta Erez of Tel Aviv University's Sackler Faculty of Medicine has now demonstrated that fibroblasts can also do a body great harm, helping to "recruit" immune cells for tumor growth.

27 Jan 2011

Researchers discover new sensory neurons that mediate BP and metabolism regulation in liver

For 60 years, scientists have puzzled over the possibility of a hepatic osmoreceptor that influences blood pressure regulation. Now, researchers of the Max Delbr-ck Center for Molecular Medicine Berlin-Buch, the Experimental and Clinical Research Center of the MDC and Charit- and the Hannover Medical School appear to have made a breakthrough discovery.

27 Jan 2011

Elimination of glucagon action may help convert Type 1 diabetes into non-insulin-dependent disorder

Type 1 diabetes could be converted to an asymptomatic, non-insulin-dependent disorder by eliminating the actions of a specific hormone, new findings by UT Southwestern Medical Center researchers suggest.

27 Jan 2011

Researchers find food-borne bacteria can cause difficult-to-treat heart infections

Researchers at the University of Illinois at Chicago College of Medicine have found that particular strains of a food-borne bacteria are able to invade the heart, leading to serious and difficult-to-treat heart infections.

27 Jan 2011

ChemoCentryx commences CCX832 Phase I trial in patients with psoriasis

ChemoCentryx, today announced the initiation of a Phase I clinical trial of CCX832, an orally-administered small molecule that is a potent and selective inhibitor of the chemoattractant receptor, ChemR23.

26 Jan 2011

Alcohol-related liver disease rising among young Britons

According to latest National Health Service (NHS) figures the number of people under 30 admitted to hospital in the past decade has risen by more than 50 per cent. 351 people aged 30 and under were admitted to an English hospital with alcohol related liver disease in 2009/10, up from 230 in 2000/01. That is still only a small fraction of the 14,500 people aged 31 or over who were admitted for alcohol-related liver problems in the last year.

26 Jan 2011

Survival following transplant surgery for liver cancer not impacted by HIV-positive status

French researchers determined that infection with human immunodeficiency virus (HIV) impaired results of transplant surgery for liver cancer, with more HIV infected patients dropping off the transplantation wait list. The team found that overall survival and recurrence-free survival was not impacted following liver transplantation in patients with controlled HIV disease.

25 Jan 2011

Liver News and Research

Study finds E2F5 transcription factor commonly overexpressed in primary human HCC

Health Canada approves Microsulis Medical's Accu2i percutaneous microwave tissue ablation system

Research sheds new light on venous thromboembolism following liver resections

New research finding shows strong relationship between gut bacteria and fatty liver

FDA approves Boston Scientific's Renegade HI-FLO Fathom Pre-Loaded System

MRI T2 can determine iron overload in beta-thalassemic patients

GATTEX Phase 3 pivotal study reaches primary efficacy endpoint of reducing PN in patients with SBS

EU grants 3.3 million to AMP for gene therapy development against AIP

New research shows CEUS can improve diagnosis of variety of medical conditions in children

Budget woes lead states to seek ways to ease Medicaid's requirements

EHSI examines business plans and product lines of OceanBASIS

HIV causes specific subset of CD4+ T-cells to age rapidly: Study

Provectus announces completion of PV-10 Phase 1 trial in patients with liver cancer

Fibroblasts help 'recruit' immune cells for tumor growth

Researchers discover new sensory neurons that mediate BP and metabolism regulation in liver

Elimination of glucagon action may help convert Type 1 diabetes into non-insulin-dependent disorder

Researchers find food-borne bacteria can cause difficult-to-treat heart infections

ChemoCentryx commences CCX832 Phase I trial in patients with psoriasis

Alcohol-related liver disease rising among young Britons

Survival following transplant surgery for liver cancer not impacted by HIV-positive status

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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