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SOM0226 (tolcapone) drug could significantly improve pharmacological treatment of ATTR

Researchers at the Institute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona (IBB-UAB), in collaboration with the biopharmaceutical company SOM Biotech, located in the Barcelona Science Park (PCB), have published, in Nature Communications, the results of a drug repositioning study in which they describe a powerful drug, SOM0226 (tolcapone) that could significantly improve the pharmacological treatment of familial transthyretin amyloidosis (ATTR).

24 Feb 2016

Novel unit can significantly speed access to specialized care for critically ill patients

A novel unit to care for critically ill patients significantly speeds access to specialized care, according to a new study by physician scientists at the University of Maryland School of Medicine and the University of Maryland Medical Center.

24 Feb 2016

New study identifies cell communication mechanism

The cells of an organism interact not only with each other but with the extracellular matrix that surrounds them. Increasing evidence is unveiling the relevance of this structure--which is secreted by the cells themselves-- for the correct function of the organism and also for the development of various diseases.

24 Feb 2016

Children less active in autumn and winter

Children should be given more support to enable them to be more active during the winter, particularly at weekends, say researchers from the University of Cambridge. Their call comes in response to their findings that children are less active and spend more time sitting in autumn and winter compared to other times of the year.

24 Feb 2016

Influenza virus can able to circumvent the body's immune system

Influenza is able to mask itself, so that the virus is not initially detected by our immune system. This is the result of new research from Aarhus University. The researchers behind the study hope that the discovery can be used to develop better treatment against influenza and chronic inflammation conditions such as rheumatoid arthritis.

24 Feb 2016

Immune cells may play greater role in Alzheimer's disease than originally thought

Immune cells that normally help us fight off bacterial and viral infections may play a far greater role in Alzheimer's disease than originally thought, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

24 Feb 2016

New BayCare Cardiovascular and Thoracic Surgery office opens at St. Anthony's Hospital

To improve access to high-quality, advanced cardiac surgery services in St. Petersburg and south Pinellas County, BayCare Health System has opened a BayCare Cardiovascular and Thoracic Surgery office at St. Anthony's Hospital.

24 Feb 2016

New TAU study suggests potential therapeutic pathway to keep osteosarcoma lesions dormant

Osteosarcoma is a cancer that develops in the bones of children and adolescents. It is one of the most aggressive cancers, with only a 15 per cent, five-year survival rate when diagnosed in an advanced metastatic stage. There are approximately 800 new cases diagnosed each year in the US, and no viable treatments.

23 Feb 2016

Alcohol consumption during pregnancy can affect multiple generations

When a mother drinks alcohol during pregnancy, even a small dose, she can increase the chances that the next three generations may develop alcoholism, according to a new study from Binghamton University.

23 Feb 2016

Diversigen, Baylor Miraca to provide customers access to targeted genomics and metabolomics services

Diversigen, Inc., the leading provider of comprehensive microbiome analysis services, today announced a strategic partnership with Baylor Miraca Genetics Laboratories, a global leader in genetic testing, to provide their customers access to a broad range of targeted genomics and metabolomics services.

23 Feb 2016

Adapted yoga feasible, beneficial for adults with stroke or traumatic brain injury

A research team, led by an IU School of Health and Rehabilitation faculty member at Indiana University-Purdue University Indianapolis, has determined that adapted yoga is both feasible and beneficial for adults with stroke or traumatic brain injury.

23 Feb 2016

ARV drug atazanavir may have significant effects on infant development

The antiretroviral (ARV) drug atazanavir—sometimes included in treatments to prevent mother-to-child HIV transmission during pregnancy—may have small but significant effects on infant development, reports a study in the journal AIDS, official journal of the International AIDS Society.

23 Feb 2016

New, non-medication treatments for children with ADHD

Teachers have long struggled to get children to sit still at their desks. But for children with ADHD, those orders might be counterproductive.

23 Feb 2016

Dapivirine ring can help prevent HIV-1 infection in women

In an important scientific achievement for women's health, two large Phase III clinical trials -- The Ring Study and ASPIRE -- have shown that a monthly vaginal ring containing the antiretroviral drug (ARV) dapivirine can safely help prevent HIV-1 infection in women.

23 Feb 2016

Researchers develop designer recombinase that can remove provirus from HIV-1 isolates

Researchers at the Medical Faculty of the Technische Universität Dresden and the Heinrich Pette Institute, Leibniz Institute for Experimental Virology succeeded in developing a designer recombinase (Brec1) that is capable of specifically removing the provirus from infected cells of most primary HIV-1 isolates.

23 Feb 2016

Poll: 59% of parents rate flu vaccine less favorably than other childhood vaccines

Parents who do not get their children flu shots rate the flu vaccine less favorably than other childhood vaccines, a national poll finds.

23 Feb 2016

New biological technique may provide better, longer-lasting joint function

According to the Agency for Healthcare Research and Quality, more than 300,000 total hip replacements are performed in the United States each year. The procedure reduces pain and restores mobility. However, for younger, more active patients, an artificial hip has a limited lifetime and usually requires restricted activity.

23 Feb 2016

New treatment for adults with lazy eye one step closer to reality

A new treatment for adults with lazy eye, a condition previously thought to be treatable only in childhood, is one step closer as a result of research from the University of Waterloo in Canada and Sun Yat-sen University in China.

23 Feb 2016

MDI Biological Laboratory scientist identifies potential drug therapy to reverse peripheral nerve damage

The Mount Desert Island Biological Laboratory has announced that assistant professor Sandra Rieger, Ph.D., has identified two drugs that could potentially be used to reverse peripheral nerve damage, or peripheral neuropathy, resulting from chemotherapy treatment for ovarian, breast, lung, pancreas and other cancers. The drugs also have potential applications for the treatment of peripheral nerve damage caused by diabetes, traumatic injuries and other conditions.

23 Feb 2016

Black, white Americans cope with pain differently

Researchers led by Adam T. Hirsh of the School of Science at Indiana University-Purdue University Indianapolis report that black and white Americans cope with pain differently and that blacks employ pain coping strategies more frequently than whites. The IUPUI review and analysis of 19 studies is the first to examine the entire published literature and quantify the relationship between race and the use of pain-coping strategies.

23 Feb 2016

Research News and Research

SOM0226 (tolcapone) drug could significantly improve pharmacological treatment of ATTR

Novel unit can significantly speed access to specialized care for critically ill patients

New study identifies cell communication mechanism

Children less active in autumn and winter

Influenza virus can able to circumvent the body's immune system

Immune cells may play greater role in Alzheimer's disease than originally thought

New BayCare Cardiovascular and Thoracic Surgery office opens at St. Anthony's Hospital

New TAU study suggests potential therapeutic pathway to keep osteosarcoma lesions dormant

Alcohol consumption during pregnancy can affect multiple generations

Diversigen, Baylor Miraca to provide customers access to targeted genomics and metabolomics services

Adapted yoga feasible, beneficial for adults with stroke or traumatic brain injury

ARV drug atazanavir may have significant effects on infant development

New, non-medication treatments for children with ADHD

Dapivirine ring can help prevent HIV-1 infection in women

Researchers develop designer recombinase that can remove provirus from HIV-1 isolates

Poll: 59% of parents rate flu vaccine less favorably than other childhood vaccines

New biological technique may provide better, longer-lasting joint function

New treatment for adults with lazy eye one step closer to reality

MDI Biological Laboratory scientist identifies potential drug therapy to reverse peripheral nerve damage

Black, white Americans cope with pain differently

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