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Fraunhofer FIT develops new Zeta software for cell division analysis

At the European Lab Automation Congress, held in Hamburg on June 6 and 7, Fraunhofer FIT demonstrates the new Zeta software for cell division analysis, which we developed for the Bayer Pharma AG. In the quest for new cancer drugs, this software supports the full workflow from cell detection to visualization and exploration.

24 May 2013

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs before it's dissolved, researchers reported in an early online publication at Nature.

24 May 2013

RUCDR Infinite Biologics creates new Genomics Technology Center

RUCDR Infinite Biologics, the world's largest university-based biorepository, has completed an $11.8 million renovation project to create a new Genomics Technology Center, comprising 12,500 square feet of laboratory, office, and storage space on the Busch Campus of Rutgers, The State University of New Jersey.

18 May 2013

CMC Biologics, RuiYi to develop a cell line for RYI-008

CMC Biologics today announced the execution of an agreement with RuiYi Inc. to develop a cell line for RYI-008, a novel anti-IL-6 monoclonal antibody.

14 May 2013

Modifications in key epigenetic markers influence human embryonic stem cells

Scientists have long known that control mechanisms known collectively as "epigenetics" play a critical role in human development, but they did not know precisely how alterations in this extra layer of biochemical instructions in DNA contribute to development.

10 May 2013

Biomedical engineers grow 3D human heart muscle that acts just like natural tissue

Duke University biomedical engineers have grown three-dimensional human heart muscle that acts just like natural tissue. This advancement could be important in treating heart attack patients or in serving as a platform for testing new heart disease medicines.

7 May 2013

Preclinical studies show bladder cancers, mesotheliomas respond to treatment with ADI-PEG 20

Scientists from academic institutions reported at the 2013 annual American Association for Cancer Research meeting, results from preclinical studies which showed that certain bladder cancers and mesotheliomas have metabolic changes and are more likely to respond to treatment with ADI-PEG 20 (pegylated arginine deiminase) if they are deficient in the enzyme, argininosuccinate synthetase.

18 Apr 2013

New research shows safety can be improved for people participating in medical experiments

In almost 90 per cent of cases, novel drugs tested on humans by pharmaceutical companies do not work as intended and must be scrapped. Often the drugs do not work, while at worst, test subjects die. New research from the University of Southern Denmark now shows that this number can be reduced.

12 Apr 2013

Cellectis CanCELL cell lines enable drug positioning in cancer pathways

CanCELL cell lines are featuring gene knock-outs of the major cancer relevant oncogenes and tumor suppressor genes. This new product line answers identified market needs in oncology research and drug discovery.

11 Apr 2013

Researchers uncover DNA rearrangement process for sex determination in Tetrahymena

It's been more than 50 years since scientists discovered that the single-celled organism Tetrahymena thermophila has seven sexes. But in all that time, they've never known how each cell's sex, or "mating type," is determined.

28 Mar 2013

Cell fusion studies at Johns Hopkins could lead to improved treatments for muscular dystrophy

Researchers at Johns Hopkins have established a high-efficiency cell-cell fusion system, providing a new model to study how fusion works. The scientists showed that fusion between two cells is not equal and mutual as some assumed, but, rather, is initiated and driven by one of the fusion partners. The discovery, they say, could lead to improved treatments for muscular dystrophy, since muscle regeneration relies on cell fusion to make muscle fibers that contain hundreds or even thousands of nuclei.

8 Mar 2013

Stem cell line could also advance research into liver cancers, cystic fibrosis

Chronic or acute, liver failure can be deadly. Toxins take over, the skin turns yellow and higher brain function slows. "There is no effective therapy at the moment to deal with the toxins that build up in your body," said Neil Talbot, a Research Animal Scientist for the USDA Agricultural Research Service. "Their only option now is to transplant a liver."

1 Mar 2013

Patient-specific cancer cell lines designed to predict chemotherapy sensitivity

In laboratory studies, scientists at the Johns Hopkins Kimmel Cancer Center have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors.

15 Feb 2013

FOXC2 vital to epithelial-mesenchymal transition in breast cancer

Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.

14 Feb 2013

Ability to tune gene activity will permit refined research for drug resistance, cancer

Scientists who built a synthetic gene circuit that allowed for the precise tuning of a gene's expression in yeast have now refined this new research tool to work in human cells, according to research published online in Nature Communications.

13 Feb 2013

Ziziphora may be effective in treatment of gastric cancer

A recent publication in the journal Food and Agricultural Immunology investigating the effects of aloe vera, ginger, saffron and ziziphora extracts as herbal remedies for gastric cancer suggests that the latter may be effective in the treatment of the fourth most common form of the disease.

13 Feb 2013

Cell Line News and Research

Fraunhofer FIT develops new Zeta software for cell division analysis

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

RUCDR Infinite Biologics creates new Genomics Technology Center

CMC Biologics, RuiYi to develop a cell line for RYI-008

Modifications in key epigenetic markers influence human embryonic stem cells

Biomedical engineers grow 3D human heart muscle that acts just like natural tissue

Preclinical studies show bladder cancers, mesotheliomas respond to treatment with ADI-PEG 20

New research shows safety can be improved for people participating in medical experiments

Cellectis CanCELL cell lines enable drug positioning in cancer pathways

Researchers uncover DNA rearrangement process for sex determination in Tetrahymena

Cell fusion studies at Johns Hopkins could lead to improved treatments for muscular dystrophy

Stem cell line could also advance research into liver cancers, cystic fibrosis

Patient-specific cancer cell lines designed to predict chemotherapy sensitivity

FOXC2 vital to epithelial-mesenchymal transition in breast cancer

Ability to tune gene activity will permit refined research for drug resistance, cancer

Ziziphora may be effective in treatment of gastric cancer

Researchers identify miR-506 as potential therapeutic candidate for metastatic ovarian cancer

Glimmer of hope for imatinib-resistant GIST

Tumor suppressor mutant may predict poor outcome in breast cancer

Quantum dots can rapidly deliver calcitriol to targeted tumor sites for treatment of IBC

Optimizing cell line development for recombinant proteins and monoclonal antibodies eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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