Embryo News and Research

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U.S. panel endorses “three-parent” IVF technique

An expert committee have recommended that the U.S. government allows the clinical investigation of mitochondrial replacement techniques (MRT) to go ahead.

4 Feb 2016

Oncofertility complications reviewed for US patients

Three articles published in JAMA Oncology highlight the legal and clinical care issues surrounding fertility preservation in US patients with cancer.

4 Feb 2016

Study reveals fetal origin for social and repetitive behavior deficits

Fetal development has been known to play an important role in social interaction, a fundamental behavior found in nearly all organisms, and later adult social behaviors. Autism, a highly heritable neurodevelopment disorder that causes difficulties with social interactions, has been postulated to be caused by neuron overgrowth in the prenatal period, although the precise timing and cause of this overgrowth has been unknown.

3 Feb 2016

Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Eisai Inc. announced today that the U.S. Food and Drug Administration approved Halaven (eribulin mesylate) Injection (0.5 mg per mL) for the treatment of patients with unresectable or metastatic liposarcoma who have received a prior anthracycline-containing regimen.

29 Jan 2016

CNIO team uses network theory to build and study first epigenetic communication network

One of the big questions for which there is still no clear answer in biology is how, based on the four universal letters that make up DNA, it is possible to generate such different organisms as a fly or a human, or the different organs and tissues they comprise. In recent years, researchers have discovered that the system is much more complicated than was originally thought.

29 Jan 2016

UI researchers uncover how cancer cells form tumors

Two University of Iowa studies offer key insights by recording in real time, and in 3-D, the movements of cancerous human breast tissue cells. It's believed to be the first time cancer cells' motion and accretion into tumors has been continuously tracked.

27 Jan 2016

Rockefeller University researchers identify new mechanism involved in early stem cell development

Stem cells work throughout our lives as a sort of handyman, repairing damaged tissues and renewing some normal ones, like the skin we shed. Scientists have come to understand much about how stem cells function when we are adults, but less is known about where these stem cells come from to begin with, as an embryo is developing.

18 Jan 2016

DNA-binding protein acts like genetic traffic signal to orchestrate early stage embryonic development

New research by UC San Francisco stem cell biologists has revealed that a DNA-binding protein called Foxd3 acts like a genetic traffic signal, holding that ball of undifferentiated cells in a state of readiness for its great transformation in the third week of development.

11 Jan 2016

New classification of coronary congenital diseases helps surgeons identify secondary defects

A new classification of coronary congenital diseases is set to help surgeons identify secondary defects in the operating theatre. The scheme is outlined in a novel European Society of Cardiology position paper published today in Cardiovascular Research.1 Clinical cardiologists will also know what to look for on cardiovascular images.

11 Jan 2016

Cornell researchers discover natural triggers that may reduce congenital heart defects among newborns

Cornell biomedical engineers have discovered natural triggers that could reduce the chance of life-threatening, congenital heart defects among newborn infants. Those triggers can override developmental, biological miscues, leading to proper embryonic heart and valve formation.

5 Jan 2016

Newly discovered mechanism may help explain why some embryos not useful for fertility treatments

It's the dream of many infertile couples: to have a baby. Tens of thousands of children are born by in vitro fertilization, or IVF, a technique commonly used when nature doesn't take its course. However, embryos obtained when a sperm fertilizes an egg in a test tube often have defects.

5 Jan 2016

Children conceived through infertility treatments no more likely to have developmental delays

Children conceived via infertility treatments are no more likely to have a developmental delay than children conceived without such treatments, according to a study by researchers at the National Institutes of Health, the New York State Department of Health and other institutions.

5 Jan 2016

Mitochondrial variation and viable pregnancy: an interview with Dr Elpida Fragouli

Embryos require adequate amounts of energy so that they can successfully progress through each of their cell divisions.

16 Dec 2015

CRISPR-Cas9 can help knock out genes in exotic animals

The simplicity of CRISPR-Cas9 gene editing will soon make studying the genes of any organism, from the simplest slime mold to the octopus, as easy as it now is to study the genes controlling development in standard lab animals such as nematodes, fruit flies, frogs and mice.

12 Dec 2015

Macrophages play key role in maintaining healthy arteries after inflammation

Researchers from the University of Toronto have found that a specific cell type plays a key role in maintaining healthy arteries after inflammation. It's a discovery that could provide treatment options for cardiovascular disease -- one of the leading causes of death in Canada.

8 Dec 2015

American scientists synthesize glycopolymers that prolong lifetime of healthy cells

Glycoproteins such as the mucins are assumed to be heavily involved in oncogenesis and metastasic spread. They are part of a strategy developed by malignant cells to resist or dodge the cell death machinery specialized for cells that show insufficient signaling through adhesions.

28 Nov 2015

Research paves way for clinical trials of cell therapies to treat Parkinson's disease, spinal cord injury

Stem cells that have been specifically developed for use as clinical therapies are fit for use in patients, an independent study of their genetic make-up suggests.

26 Nov 2015

More hormone treatments decrease women's chances of having baby

A Michigan State University study has found that too much of a hormone commonly used during in vitro fertility, or IVF, treatments actually decreases a woman's chances of having a baby.

24 Nov 2015

Finding may lead to better understanding of male genital birth defects

University of Florida Health researchers have identified genes that are disrupted by abnormal hormone signaling at crucial points during development, a finding that may lead to a better understanding of how the most common male genital birth defects arise in humans.

24 Nov 2015

EMBL scientists develop new laser technique to prevent cells from contracting

You were once a hollow shell. To sculpt that hollow ball into an organism with layers of internal organs, muscle and skin, portions of that embryonic 'shell' folded inwards. The same happens to fruit fly embryos, and researchers at the European Molecular Biology Laboratory in Heidelberg, Germany, have now identified a particular group of cells which are crucial for the first such fold.

23 Nov 2015

Embryo News and Research

U.S. panel endorses “three-parent” IVF technique

Oncofertility complications reviewed for US patients

Study reveals fetal origin for social and repetitive behavior deficits

Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

CNIO team uses network theory to build and study first epigenetic communication network

UI researchers uncover how cancer cells form tumors

Rockefeller University researchers identify new mechanism involved in early stem cell development

DNA-binding protein acts like genetic traffic signal to orchestrate early stage embryonic development

New classification of coronary congenital diseases helps surgeons identify secondary defects

Cornell researchers discover natural triggers that may reduce congenital heart defects among newborns

Newly discovered mechanism may help explain why some embryos not useful for fertility treatments

Children conceived through infertility treatments no more likely to have developmental delays

Mitochondrial variation and viable pregnancy: an interview with Dr Elpida Fragouli

CRISPR-Cas9 can help knock out genes in exotic animals

Macrophages play key role in maintaining healthy arteries after inflammation

American scientists synthesize glycopolymers that prolong lifetime of healthy cells

Research paves way for clinical trials of cell therapies to treat Parkinson's disease, spinal cord injury

More hormone treatments decrease women's chances of having baby

Finding may lead to better understanding of male genital birth defects

EMBL scientists develop new laser technique to prevent cells from contracting

Industry Focus eBook - Cell biology (5th edition) eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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