Malignant News and Research

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Researchers decipher how the immune system memorizes pathogens after an infection

The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. Now, scientists at the University of Würzburg have deciphered new details of this process.

28 Sep 2020

Interdisciplinary team wins NIH grant to develop a device for early oral cancer detection

Mouth lesions are among the main early indicators of oral cancer, but determining whether a sore is actually malignant typically involves painful, costly biopsies.

28 Sep 2020

Biomarker candidates could aid in earlier diagnosis of mesothelioma

Mesothelioma is a deadly cancer mainly caused by exposure to asbestos fibers. Unfortunately, mesothelioma is generally diagnosed at an already advanced stage and none of the therapeutic strategies tried so far is able to eradicate the disease.

24 Sep 2020

Discovery could help enhance the effectiveness of immunotherapy against melanoma

Researchers at the University of Bern have discovered a mechanism in the body’s own immune system which is responsible for the maturation and activation of immune cells.

19 Sep 2020

Hannover and Rostock team up to develop non-invasive optical melanoma diagnostics

Leibniz University Hannover and Rostock University Medical Center receive funding for the development of non-invasive optical melanoma diagnostics.

17 Sep 2020

PET/MRI reduces radiation exposure, improves lesion detectability in select cancers

A single-center observational study of more than 1,000 oncological examinations has demonstrated that positron emission tomography/magnetic resonance imaging (PET/MRI) facilitates cancer staging as well as PET/computed tomography (PET/CT) and improves lesion detectability in select cancers, potentially helping to promote fast, efficient local and whole-body staging in one step.

17 Sep 2020

Data scientists use Zhores supercomputer to identify the severity of COVID-19

As part of the anti-COVID-19 program of the Skoltech Center for Computational and Data-Intensive Science and Engineering (CDISE), Care Mentor AI data scientists used Skoltech's Zhores supercomputer to enhance pathology detection accuracy.

17 Sep 2020

First clinical trial launched to test psilocybin therapy for depression in cancer patients

The first clinical trial to test the safety and feasibility of psilocybin therapy with simultaneous administration and one-on-one patient support to treat depression in cancer patients was launched today by Maryland Oncology Hematology at the Aquilino Cancer Center at Adventist HealthCare Shady Grove Medical Center.

16 Sep 2020

Study provides insight into lymphomagenesis and patterns of resistance to immunotherapy

Lymphomas are a diverse group of cancers of the immune system, which is the body's primary defense against autoimmune disease, infections, and malignancy.

16 Sep 2020

WSU researchers use soy to improve post-operative treatment of bone cancer

Researchers in recent years have demonstrated the health benefits of soy, linking its consumption to reduced risk of cardiovascular disease, obesity, cancer and improved bone health.

15 Sep 2020

Researchers receive $2.5 million grant to develop and analyze breast tumor organoids

Breast cancer is the second most common cancer diagnosed in women in the United States after skin cancer, and women with comorbidities (the presence of more than one condition/disease) often fare worse in terms of their breast cancer.

14 Sep 2020

New antitumor vaccines control melanoma growth in preclinical models

Combining their expertise in protein engineering and synthetic DNA technology, scientists at The Wistar Institute successfully delivered nanoparticle antitumor vaccines that stimulated robust CD8 T cell immunity and controlled melanoma growth in preclinical models.

11 Sep 2020

Novel liver cancer treatment could shrink tumors in a mouse model

Hepatocellular carcinoma is a common liver cancer with poor prognosis. With symptoms not discovered until later stages, it is considered the most fatal malignant liver cancer worldwide.

10 Sep 2020

Nanotechnological drug delivery system enhances the effectiveness of melanoma treatment

Researchers at Tel Aviv University, led by Prof. Ronit Satchi-Fainaro of TAU's Department of Physiology and Pharmacology at the Sackler School of Medicine, have developed an innovative nanotechnological drug delivery system that significantly enhances the effectiveness of treatment for the aggressive skin cancer melanoma.

8 Sep 2020

Personalized determination of genetic factors may improve treatment for polycythaemia vera

Polycythaemia vera is a chronic malignant disease of the haematopoietic system and is treated with interferon-alpha-based drugs, in most cases with long-lasting success. However, in some cases this therapy is unsuccessful for reasons that are not yet understood.

8 Sep 2020

Suppressing tumor's growth and spread from the inside

A new technology that allows researchers to peer inside malignant tumors shows that two experimental drugs can normalize aberrant blood vessels, oxygenation, and other aspects of the tumor microenvironment in non-small cell lung cancer, helping to suppress the tumor's growth and spread, UT Southwestern researchers report.

3 Sep 2020

Study identifies subtypes and developmental process of novel immune T cells

There are memory cells that remember previously encountered pathogens and help to react quickly and strongly when exposed to them again.

2 Sep 2020

FDA grants rare disease designations to investigational brain tumor drug

The U.S. Food and Drug Administration has awarded Rare Pediatric Disease Designation (RPDD) for diffuse intrinsic pontine glioma (DIPG) and Orphan Drug Designation for treatment of malignant glioma to OKN-007, an investigational drug discovered at the Oklahoma Medical Research Foundation and being developed by Oblato, Inc.

2 Sep 2020

FEFU scientists to design genetically modified models for understanding malignant gliomas

Scientists of Far Eastern Federal University get started studying the formation and survival mechanisms of the brain malignant tumors cells, i.e. glioma, to reveal new ways for diagnosis and therapy for this fatal disease.

31 Aug 2020

Researchers find way to make pediatric brain cancers respond better to therapies

Brain cancer in children is always a devastating diagnosis, but McMaster University researchers may have found a way to have the most serious types of pediatric brain cancer respond better to therapies.

28 Aug 2020

Malignant News and Research

Researchers decipher how the immune system memorizes pathogens after an infection

Interdisciplinary team wins NIH grant to develop a device for early oral cancer detection

Biomarker candidates could aid in earlier diagnosis of mesothelioma

Discovery could help enhance the effectiveness of immunotherapy against melanoma

Hannover and Rostock team up to develop non-invasive optical melanoma diagnostics

PET/MRI reduces radiation exposure, improves lesion detectability in select cancers

Data scientists use Zhores supercomputer to identify the severity of COVID-19

First clinical trial launched to test psilocybin therapy for depression in cancer patients

Study provides insight into lymphomagenesis and patterns of resistance to immunotherapy

WSU researchers use soy to improve post-operative treatment of bone cancer

Researchers receive $2.5 million grant to develop and analyze breast tumor organoids

New antitumor vaccines control melanoma growth in preclinical models

Novel liver cancer treatment could shrink tumors in a mouse model

Nanotechnological drug delivery system enhances the effectiveness of melanoma treatment

Personalized determination of genetic factors may improve treatment for polycythaemia vera

Suppressing tumor's growth and spread from the inside

Study identifies subtypes and developmental process of novel immune T cells

FDA grants rare disease designations to investigational brain tumor drug

FEFU scientists to design genetically modified models for understanding malignant gliomas

Researchers find way to make pediatric brain cancers respond better to therapies

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