Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Scientists identify key molecules that mediate radioresistance in aggressive brain cancer

Scientists have identified key molecules that mediate radioresistance in glioblastoma multiforme; these molecules are a potential target for the treatment of this brain cancer.

30 Sep 2020

Antibody improves progression-free survival in patients with advanced prostate cancer

An antibody for treating advanced prostate cancer improves progression-free survival in patients with metastasised, castration-resistant prostate cancer.

29 Sep 2020

New strategic collaboration to accelerate treatments for unmet medical needs in oncology

The University of Texas MD Anderson Cancer Center and Taiho Pharmaceutical Co., Ltd., today announced a three-year strategic collaboration to accelerate the development of treatments for significant unmet medical needs in oncology, including patients with brain metastases and those with cancers refractory to available therapies.

25 Sep 2020

Cellular recyclers could be used to eliminate the driver of cancer's aggressiveness

"Do not erase." "Recycle me." "Free to a good home." Humans post these signs to indicate whether something has value or not, whether it should be disposed of or not.

18 Sep 2020

Breakthrough discovery could turn cancer into a treatable disease

Professor Michael Lisanti and Professor Federica Sotgia have made a discovery that could turn cancer into a treatable disease and remove the fear from a cancer diagnosis.

16 Sep 2020

New research reverses the understanding of kidney tumor growth

Newly published research has reversed our understanding of an aspect of kidney tumor growth. Researchers at Huntsman Cancer Institute at the University of Utah (U of U) discovered that two key proteins have opposite roles than what was previously believed.

12 Sep 2020

A novel gene involved in primary lymphedema identified

The Human Molecular Genetics laboratory of the de Duve Institute (UCLouvain), headed by Professor Miikka Vikkula, recently identified mutations in a novel gene, ANGPT2, responsible for primary lymphedema.

10 Sep 2020

Honeybee venom induces cancer cell death in aggressive breast cancer

The new study, published in the journal Nature Precision Oncology, highlights how bees can help combat breast cancer. The research team found that when the venom’s main component, when mixed with existing chemotherapy drugs, reduced tumor growth in laboratory mice.

2 Sep 2020

Scientists identify key driver in BRAF inhibitor resistant melanoma

Targeted therapy with BRAF-MEK inhibitors is an effective treatment for patients with advanced melanoma that cannot be surgically removed or has spread to other areas of the body.

2 Sep 2020

Cancer cells reshape, destroy or integrate into blood vessels to spread

In laboratory studies, Johns Hopkins Kimmel Cancer Center and Johns Hopkins University researchers observed a key step in how cancer cells may spread from a primary tumor to a distant site within the body, a process known as metastasis.

1 Sep 2020

'Natural killer' cells could be a powerful weapon to fight against lung cancer

Immune cells called 'natural killer' (NK) cells could be a powerful weapon for fighting lung cancer, according to Australian researchers.

1 Sep 2020

Scientists combine 3D bioprinting and computer modeling to study cancer metastasis in blood vessels

Lawrence Livermore National Laboratory scientists have paired 3D-printed, living human brain vasculature with advanced computational flow simulations to better understand tumor cell attachment to blood vessels, the first step in secondary tumor formation during cancer metastasis.

26 Aug 2020

Researchers identify potential drug target for curtailing cancer metastasis

Researchers led by Ludwig Chicago Co-director Ralph Weichselbaum and Ronald Rock of the University of Chicago have identified in preclinical studies a potential drug target for curtailing cancer metastasis.

24 Aug 2020

Researchers find a new way to slow colon cancer metastasis

When cancer metastasizes and spreads throughout the body, it can severely change the prognosis of the disease. It is estimated that metastasis is responsible for 90 percent of cancer deaths.

24 Aug 2020

Newly discovered molecule can suppress a wide range of cancers

Scientists at Scripps Research have discovered a molecule that can activate a natural immune-boosting protein called STING.

21 Aug 2020

Sortilin may hold the key to developing more effective treatment for pancreatic cancer

Pancreatic cancer has an extremely poor prognosis; it is the third most common cause of cancer deaths in the United States.

20 Aug 2020

Study may lead to new targeted therapies that inhibit the spread of cancer

For decades, physicians have known that many kinds of cancer cells often spread first to lymph nodes before traveling to distant organs through the bloodstream.

20 Aug 2020

Enzalutamide has added benefit for men with castration-resistant prostate cancer at high risk of metastasis

In 2018 and 2019, the German Institute for Quality and Efficiency in Health Care already investigated whether the drug enzalutamide has an advantage in comparison with the appropriate comparator therapy, i.e. in comparison with watchful waiting while maintaining ongoing conventional androgen deprivation therapy (ADT), for adult men with high-risk non-metastatic castration-resistant prostate cancer.

19 Aug 2020

Study shows how PIM kinases enhance cancer cell motility

PIM kinases are enzymes that promote metastatic growth and spread of cancer cells. Researchers from the University of Turku, Finland, have obtained new information on how the PIM kinases enhance cancer cell motility by regulating the formation of actin fibers in the cytoskeleton.