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UAB researchers report a potential treatment for ARID1A-deficient bladder cancer

Metastatic bladder cancer is generally incurable, so new therapies are an urgent need. Researchers at the University of Alabama at Birmingham now report a potential treatment for a quarter of bladder cancers.

4 Aug 2022

Early-life acquisition of antibiotic resistance in neonates from developing countries

Every year, almost 7 million potentially serious bacterial infections are estimated to occur in newborns, resulting in more than 550,000 annual neonatal deaths.

4 Aug 2022

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Mitochondria are organelles found within most cells, best known for generating the chemical energy required to power cellular functions.

4 Aug 2022

What is the severity of SARS-CoV-2 Omicron BA.4 and BA.5 variant infections in relation to BA.2 infections?

Researchers compared clinical outcomes of COVID-19 cases due to SARS-CoV-2 Omicron BA.2 and Omicron BA.4/BA.5 variants based on the Kaiser Permanente Southern California (KPSC) health records between April 29 and July 2, 2022.

4 Aug 2022

CHOP helps launch new computational platform to harmonize pediatric cancer data

Children's Hospital of Philadelphia has helped launch a new computational platform that will harmonize pediatric cancer data, allowing researchers, pharmaceutical companies, and advocacy groups to accelerate the pace of drug development for pediatric cancer.

4 Aug 2022

Monoclonal antibody protects U.S. adults from malaria, Phase 1 clinical trial shows

One injection of a candidate monoclonal antibody (mAb) known as L9LS was found to be safe and highly protective in U.S. adults exposed to the malaria parasite, according to results from a National Institutes of Health Phase 1 clinical trial published in The New England Journal of Medicine.

4 Aug 2022

Higher suPAR levels linked with increased risk of blood clot formation

Blood clots are thought to occur in as many as a third of patients hospitalized with COVID-19. In many cases these clots can be deadly, such as pulmonary embolisms - blood clots that travel to the lungs. In fact, in nearly one third of patients with COVID-19, these clots led to death.

4 Aug 2022

‘Children are not little adults’ and need special protection during heat waves

After more than a week of record-breaking temperatures across much of the country, public health experts are cautioning that children are more susceptible to heat illness than adults are — even more so when they're on the athletic field, living without air conditioning, or waiting in a parked car.

4 Aug 2022

When mental illness leads to dropped charges, patients often go without stabilizing care

For seven years, Timothy Jay Fowler rotated between jail, forced psychiatric hospitalization, and freedom.

4 Aug 2022

A California man’s ‘painful and terrifying’ road to a monkeypox diagnosis

Two days after Kevin Kwong flew home to California from New York, his hands itched so badly, the pain jolted him from sleep. He thought the problem was eczema.

4 Aug 2022

Was there a benefit of vaccinating health care workers with a fourth dose of BNT162b2 vaccine during the Omicron outbreak?

Researchers analyzed the effectiveness of the fourth dose of the SARS-CoV-2 BNT162b2 vaccination against the SARS-CoV-2 Omicron infection in medical professionals in Israel.

4 Aug 2022

Can high-dose coenzyme Q10 reduce the number and severity of post-COVID-19 condition-related symptoms?

Investigators assessed the potential of high-dose coenzyme Q10 treatment for long coronavirus disease.

4 Aug 2022

Pregnant women with IBD and their babies face increased risks and complications

Pregnant women with inflammatory bowel disease (IBD) and their babies face increased risks and complications compared to pregnant women without IBD.

3 Aug 2022

Persistent viral infections within hosts cause post-acute sequelae of COVID-19, research shows

A research team, comprised of Associate Professor Tomonari Sumi of the Research Institute for Interdisciplinary Science at Okayama University and Associate Professor Kouji Harada of the Center for IT-based Education at Toyohashi University of Technology, has developed a mathematical model of the immune response within infected hosts that considers systemic infection of a novel coronavirus (SARS-CoV-2), and demonstrated by conducting experimental computer simulations that persistent viral infections within hosts potentially cause long COVID or post-acute sequelae of COVID-19.

3 Aug 2022

Women with a history of hypertensive disorders of pregnancy more likely to develop dementia

Hypertensive disorders of pregnancy (HDP) — conditions of high blood pressure including chronic/gestational hypertension and preeclampsia — have been strongly linked to heart disease in later life, but, before today, little research has connected these disorders with cognition.

3 Aug 2022

Hospital News and Research

UAB researchers report a potential treatment for ARID1A-deficient bladder cancer

Early-life acquisition of antibiotic resistance in neonates from developing countries

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

What is the severity of SARS-CoV-2 Omicron BA.4 and BA.5 variant infections in relation to BA.2 infections?

CHOP helps launch new computational platform to harmonize pediatric cancer data

Monoclonal antibody protects U.S. adults from malaria, Phase 1 clinical trial shows

Higher suPAR levels linked with increased risk of blood clot formation

‘Children are not little adults’ and need special protection during heat waves

When mental illness leads to dropped charges, patients often go without stabilizing care

A California man’s ‘painful and terrifying’ road to a monkeypox diagnosis

Was there a benefit of vaccinating health care workers with a fourth dose of BNT162b2 vaccine during the Omicron outbreak?

Can high-dose coenzyme Q10 reduce the number and severity of post-COVID-19 condition-related symptoms?

Pregnant women with IBD and their babies face increased risks and complications

Persistent viral infections within hosts cause post-acute sequelae of COVID-19, research shows

Women with a history of hypertensive disorders of pregnancy more likely to develop dementia

Lower efficacy of COVID-19 mRNA vaccines in patients with frailty

What is the prevalence of carbapenem-resistant Enterobacterales among individuals with and without health risk factors?

Case series of first 3 monkeypox patients in Massachusetts treated with tecoviromat

Memory B and T cell responses to the SARS-CoV-2 spike protein before and after the third BNT162b2 booster

They lost Medicaid when paperwork was sent to an empty field, signaling the mess to come

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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