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FDA weighs approval of a lucrative Alzheimer’s drug but benefits are iffy

The Food and Drug Administration's decision next week whether to approve the first treatment for Alzheimer's disease highlights a deep division over the drug's benefits as well as criticism about the integrity of the FDA approval process.

4 Jun 2021

Post-COVID-19 assessment shows long-lasting consequences for many non-hospitalized individuals

Complications following COVID-19 infection require quick identification and management to help plan policy and health system responses. Researchers in the UK recently described the 12-month experience of the first dedicated post-COVID clinical service in the UK to include both hospitalized and non-hospitalized COVID-19 patients. This study has been released on the medRxiv* the preprint server.

4 Jun 2021

A lack of oversight for unproven stem cell interventions is a global public health problem

Authors are urging the WHO to establish an Exert Advisory Committee on Regenerative Medicine to provide harmony to the national regulations on the SCI industry.

4 Jun 2021

Researchers test the impact of deploying artificial intelligence for radiation cancer therapy

The impact of deploying Artificial Intelligence (AI) for radiation cancer therapy in a real-world clinical setting has been tested by Princess Margaret researchers in a unique study involving physicians and their patients.

4 Jun 2021

Study: Nasal therapy is more effective than commonly used IgG antibodies at neutralizing COVID-19 virus

A nasal therapy, built upon on the application of a new engineered IgM antibody therapy for COVID-19, was more effective than commonly used IgG antibodies at neutralizing the COVID-19 virus in animal models, according to research recently published by The University of Texas Health Science Center at Houston (UTHealth), The University of Texas Medical Branch at Galveston (UTMB Health), the University of Houston, and IGM Biosciences, Inc.

4 Jun 2021

Two repurposed drugs inhibit SARS-CoV-2 entry factors in a synergistic manner

A preprint paper uploaded to the bioRxiv* server shows how combining drugs targeting different entry factors of the host cell may prevent infection by the virus.

3 Jun 2021

UC San Diego Health offers new immunotherapy treatment for multiple myeloma following FDA approval

Following the Food and Drug Administration's approval, UC San Diego Health is the first designated medical center in San Diego certified to offer a new immunotherapy treatment of multiple myeloma outside of a clinical trial.

3 Jun 2021

Immunotherapy after surgery offers recurrence-free survival advantage for patients with high-risk melanoma

Patients with high-risk melanoma who had a course of pembrolizumab after their surgery had a longer time before their disease recurred than patients who got either ipilimumab or high-dose interferon after surgery.

3 Jun 2021

New clinical guidelines to manage insomnia with intensive behavioral therapy

If insomnia keeps you awake at night, Flinders University researchers recommend a trip to the doctor - not for a sleeping pill prescription but for a short course of intensive behavioral therapy.

3 Jun 2021

New therapeutic approach developed to treat psoriatic arthritis

An international team of researchers, led by UC Davis Health, has developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory disease affecting the joints.

3 Jun 2021

Research opens alternative therapeutic avenues for treatment of chronic pain

Building on previous findings, scientists have demonstrated that conolidine interacts with the newly identified opioid receptor ACKR3/CXCR7.

3 Jun 2021

Bilingualism allows autistic children to compensate for certain fundamental deficits

Affecting more than one in a hundred children, autism spectrum disorder is one of the most common neurodevelopmental disorders.

3 Jun 2021

Oncologists underestimate patient use of complementary medicine after breast cancer diagnosis

Nearly three-quarters of breast cancer patients (73%) report using at least one type of complementary medicine after cancer diagnosis, while oncologists believe that less than half (43%) of patients are using these approaches during cancer care.

3 Jun 2021

Scientists identify many existing drugs with antiviral activity against coronavirus

Mining the world's most comprehensive drug repurposing collection for COVID-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that's driving the ongoing global pandemic.

3 Jun 2021

How can nanomaterials help in the fight against COVID-19?

Researchers have reviewed different types of nanomaterials and how they can be used for the detection, prevention, and treatment of coronavirus disease 2019 (COVID-19).

3 Jun 2021

FDA alerts health care providers to no longer implant heart failure patients with Medtronic's HVAD System

The U.S. Food and Drug Administration is alerting health care providers to no longer implant end-stage heart failure patients with Medtronic's Heartware Ventricular Assist Device (HVAD) System due to a growing body of observational clinical comparisons that demonstrates a higher frequency of neurological adverse events and mortality associated with the system when compared to other commercially available devices, as well as complaints that the internal pump may delay or fail to restart.

3 Jun 2021

New nano-sized particles help improve detection of tumors within the body

Nano-sized particles have been engineered in a new way to improve detection of tumors within the body and in biopsy tissue, a research team in Sweden reports. The advance could enable identifying early stage tumors with lower doses of radiation.

3 Jun 2021

New class of hydrogels can enable precise drug delivery

Hydrogels are commonly used inside the body to help in tissue regeneration and drug delivery. However, once inside, they can be challenging to control for optimal use. A team of researchers in the Department of Biomedical Engineering at Texas A&M University is developing a new way to manipulate the gel -- by using light.

3 Jun 2021

Centivax and US Naval Medical Research Center to begin Phase I clinical trial of antibody therapeutics

Centivax Inc. announced today that it has entered into a strategic partnership with the U.S. Naval Medical Research Center (NMRC) for Phase I clinical development of Centi-B9, Centivax's SARS-CoV-2 broad-spectrum injectable antibody therapeutic and prophylactic.

3 Jun 2021

Study: Lung squamous patients harboring druggable mutations have lower median overall survival

Oncotarget published "Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations" which reported that unlike lung adenocarcinoma patients, there is no FDA-approved targeted-therapy likely to benefit lung squamous cell carcinoma patients.

3 Jun 2021

Therapy News and Research

FDA weighs approval of a lucrative Alzheimer’s drug but benefits are iffy

Post-COVID-19 assessment shows long-lasting consequences for many non-hospitalized individuals

A lack of oversight for unproven stem cell interventions is a global public health problem

Researchers test the impact of deploying artificial intelligence for radiation cancer therapy

Study: Nasal therapy is more effective than commonly used IgG antibodies at neutralizing COVID-19 virus

Two repurposed drugs inhibit SARS-CoV-2 entry factors in a synergistic manner

UC San Diego Health offers new immunotherapy treatment for multiple myeloma following FDA approval

Immunotherapy after surgery offers recurrence-free survival advantage for patients with high-risk melanoma

New clinical guidelines to manage insomnia with intensive behavioral therapy

New therapeutic approach developed to treat psoriatic arthritis

Research opens alternative therapeutic avenues for treatment of chronic pain

Bilingualism allows autistic children to compensate for certain fundamental deficits

Oncologists underestimate patient use of complementary medicine after breast cancer diagnosis

Scientists identify many existing drugs with antiviral activity against coronavirus

How can nanomaterials help in the fight against COVID-19?

FDA alerts health care providers to no longer implant heart failure patients with Medtronic's HVAD System

New nano-sized particles help improve detection of tumors within the body

New class of hydrogels can enable precise drug delivery

Centivax and US Naval Medical Research Center to begin Phase I clinical trial of antibody therapeutics

Study: Lung squamous patients harboring druggable mutations have lower median overall survival

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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