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Death rates after surgery: an interview with Dr Rupert Pearse

There are very few published estimates describing the number of deaths following surgery at a national level and none at an international level.

1 Oct 2012

Combination of dabrafenib and trametinib delays development of treatment resistance in MM patients

Combined treatment with two drugs targeting different points in the same growth-factor pathway delayed the development of treatment resistance in patients with BRAF-positive metastatic malignant melanoma.

1 Oct 2012

New insights on global fight to prevent cancers

New insights on the global fight to prevent cancers were presented during the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna. The studies highlight the challenges of overcoming misunderstandings about how important lifestyle factors are in reducing cancer risk.

1 Oct 2012

Researchers identify IL-27 molecule involved in counterbalancing the immune system attack

We couldn't live without our immune systems, always tuned to detect and eradicate invading pathogens and particles. But sometimes the immune response goes overboard, triggering autoimmune diseases like lupus, asthma or inflammatory bowel disease.

29 Sep 2012

Wage disparities could limit success of health-care reform

A national study has found that earnings over the course of the careers of primary-care physicians averaged as much as $2.8 million less than the earnings of their specialist colleagues, potentially making primary care a less attractive choice for medical school graduates and exacerbating the already significant shortage of medical generalists.

29 Sep 2012

U.S. Pharmacopeial announces winners of 2012-13 Global Fellowship awards

Since the program's inception more than thirty years ago, USP has invested nearly $4 million in over 200 fellowship awards.

28 Sep 2012

Researchers discover leptin hormone in fruit flies

Researchers have discovered in fruit flies a key metabolic hormone thought to be the exclusive property of vertebrates. The hormone, leptin, is a nutrient sensor, regulating energy intake and output and ultimately controlling appetite.

28 Sep 2012

Melatonin supplementation improves sleep in hypertensive patients on beta-blockers

Over 20 million people in the United States take beta-blockers, a medication commonly prescribed for cardiovascular issues, anxiety, hypertension and more. Many of these same people also have trouble sleeping, a side effect possibly related to the fact that these medications suppress night-time melatonin production. Researchers at Brigham and Women's Hospital (BWH) have found that melatonin supplementation significantly improved sleep in hypertensive patients taking beta-blockers.

28 Sep 2012

Molecular link between spinal muscular atrophy and amyotrophic lateral sclerosis

Researchers of motor neuron diseases have long had a hunch that two fatal diseases, amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), might somehow be linked. A new study confirms that this link exists.

28 Sep 2012

Inhibiting TRPV4 protects against diet-induced obesity, inflammation and insulin resistance

Ember Therapeutics, Inc., a company harnessing breakthroughs in brown fat biology and insulin sensitization to revolutionize the treatment of metabolic disease, today announced the publication of key preclinical data demonstrating that inhibition of the Transient Receptor Potential Vanilloid (TRPV) family of ion channels - specifically TRPV4 - resulted in activation of brown/beige fat and protection from diet-induced obesity, inflammation and insulin resistance. Ember holds an exclusive option to license these TRPV4 findings and technology.

28 Sep 2012

UCSD receives NCI grant to continue research into chronic lymphocytic leukemia

An international consortium of scientists studying chronic lymphocytic leukemia (CLL), based at the University of California, San Diego School of Medicine, has been awarded a 5-year, $20 million grant by the National Cancer Institute, part of the National Institutes of Health.

28 Sep 2012

Cherry intake reduces risk of gout attacks

A new study found that patients with gout who consumed cherries over a two-day period showed a 35% lower risk of gout attacks compared to those who did not eat the fruit.

28 Sep 2012

Coalition for Pulmonary Fibrosis announces winners of 2012 annual awards for distinguished service

The Coalition for Pulmonary Fibrosis (CPF) proudly announces the winners of its three annual awards for distinguished service. Each honoree has made vital contributions to the effort to fight Pulmonary Fibrosis (PF) – in research, humanitarian and advocacy efforts.

28 Sep 2012

George Mason University research makes big breakthrough in HIV

New research showing how the HIV virus targets "veterans" or memory T-cells could change how drugs are used to stop the virus, according to new research by George Mason University.

27 Sep 2012

Cancer Institute of New Jersey to benefit from Panera Bread's Pink Ribbon Bagel

For more than a decade, "thinking pink" has been a tradition for Panera Bread bakery-cafés in their effort to highlight breast cancer awareness in their local communities during the month of October. That campaign, which marks National Breast Cancer Awareness Month, continues this year, with the offering of the Pink Ribbon Bagel.

27 Sep 2012

GW to evaluate effectiveness of glucose-lowering drugs against type 2 diabetes

John Lachin, professor of biostatistics, epidemiology and statistics at the George Washington University, has been awarded a five-year, $134 million grant from the National Institute of Health's National Institute of Diabetes and Digestive and Kidney Diseases to conduct a clinical trial examining the long-term effectiveness of several glucose-lowering medications for treatment of people with type 2 diabetes. The grant sets a record as the largest sum award GW has ever received.

27 Sep 2012

Study looks at rapid-onset dystonia-parkinsonism that has no known treatment

Fewer than 100 people in the world are known to be affected by a movement disorder called rapid-onset dystonia-parkinsonism (RDP), but its symptoms are life-changing. Seemingly normal young people are suddenly and dramatically unable to control movement of their arms or legs and have trouble speaking or swallowing. A normal life is nearly impossible.

27 Sep 2012

MicroRNA processing in fat tissue plays a major role in aging and stress resistance

As part of their ongoing research investigating the biology of aging, the greatest risk factor for type 2 diabetes and other serious diseases, scientists at Joslin Diabetes Center have identified a new factor - microRNA processing in fat tissue - which plays a major role in aging and stress resistance.

27 Sep 2012

Developing world lagging in anesthesia safety

Mortality after general anesthesia has declined over the past 50 years, but the greatest gains have been in developed countries, shows a systematic review in The Lancet.

26 Sep 2012

Dexamethasone use during tonsillectomy not associated with excessive bleeding in children

Tonsillectomy is exceedingly common, with a reported increase in tonsillectomy rates in children younger than 15 years from 287,000 to 530,000 per year over the past decade. Although safe, adenotonsillectomy can result in significant complications, such as aspiration and bleeding. Complications are infrequent, but because tonsillectomy is so common, the absolute number of children experiencing tonsillectomy complications is formidable.

26 Sep 2012

Medical School News and Research

Death rates after surgery: an interview with Dr Rupert Pearse

Combination of dabrafenib and trametinib delays development of treatment resistance in MM patients

New insights on global fight to prevent cancers

Researchers identify IL-27 molecule involved in counterbalancing the immune system attack

Wage disparities could limit success of health-care reform

U.S. Pharmacopeial announces winners of 2012-13 Global Fellowship awards

Researchers discover leptin hormone in fruit flies

Melatonin supplementation improves sleep in hypertensive patients on beta-blockers

Molecular link between spinal muscular atrophy and amyotrophic lateral sclerosis

Inhibiting TRPV4 protects against diet-induced obesity, inflammation and insulin resistance

UCSD receives NCI grant to continue research into chronic lymphocytic leukemia

Cherry intake reduces risk of gout attacks

Coalition for Pulmonary Fibrosis announces winners of 2012 annual awards for distinguished service

George Mason University research makes big breakthrough in HIV

Cancer Institute of New Jersey to benefit from Panera Bread's Pink Ribbon Bagel

GW to evaluate effectiveness of glucose-lowering drugs against type 2 diabetes

Study looks at rapid-onset dystonia-parkinsonism that has no known treatment

MicroRNA processing in fat tissue plays a major role in aging and stress resistance

Developing world lagging in anesthesia safety

Dexamethasone use during tonsillectomy not associated with excessive bleeding in children

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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