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Researchers uncover novel function of Amyloid Precursor Protein linked to Alzheimer's disease

A research team led by the National Neuroscience Institute has uncovered a novel function of the Amyloid Precursor Protein (APP), one of the main pathogenic culprits of Alzheimer's disease. This discovery may help researchers understand how the protein goes awry in the brains of Alzheimer's disease patients, and potentially paves the way for the development of innovative therapeutics to improve the brain function of dementia patients.

22 Apr 2014

New genetic evidence strengthens link between role of dietary fats with colon cancer progression

Scientists have shown new genetic evidence that could strengthen the link between the role of dietary fats with colon cancer progression.

22 Apr 2014

FDA approves molecularly targeted drug as second-line treatment for advanced stomach cancer

Based on results of a clinical trial led by Dana-Farber Cancer Institute scientists, the U.S. Food and Drug Administration approved a molecularly targeted drug as second-line treatment in advanced stomach cancer that has progressed after standard chemotherapy has failed.

22 Apr 2014

New approach may help reduce use of antipsychotics and other psychiatric drugs in dementia patients

A new approach to handling agitation, aggression and other unwanted behaviors by people with dementia may help reduce the use of antipsychotics and other psychiatric drugs in this population, and make life easier for them and their caregivers, a team of experts says.

22 Apr 2014

Scientists receive federal grant to track how multi-walled carbon nanotubes interact with human cells

Scientists at The University of Texas at Dallas have received a federal grant to investigate how tiny carbon structures used in the manufacture of many everyday products might affect human health.

22 Apr 2014

Researchers develop simple assay that reveals evolutionary relationships among various tumor sites within patient

The process of metastasis - a tumor's ability to spread to other parts of the body - is still poorly understood. It is not easy to determine whether metastasis began early or late in the development of the primary tumor or whether individual metastatic sites were seeded directly from the original tumor or from an intermediate site.

22 Apr 2014

Study points to new therapeutic strategy for treating depression

A new study points to a conceptually novel therapeutic strategy for treating depression. Instead of dampening neuron firing found with stress-induced depression, researchers demonstrated for the first time that further activating these neurons opens a new avenue to mimic and promote natural resilience.

21 Apr 2014

DePuy Synthes CMF announces launch of Patient Specific Plates for Mandible

DePuy Synthes CMF, a leader in skeletal and soft tissue repair and reconstruction and part of the DePuy Synthes Companies of Johnson & Johnson, announced the launch of Patient Specific Plates for Mandible (PSPM), new plates that are customized based on surgeon specifications and individual patient anatomy.

21 Apr 2014

IV-administered ketamine effective in patients with chronic PTSD

For the first time, evidence that a single dose of IV-administered ketamine was associated with the rapid reduction of symptoms of post-traumatic stress disorder in patients with chronic PTSD was demonstrated in a proof-of-concept, randomized, double blind crossover study, undertaken by researchers at the Icahn School of Medicine at Mount Sinai in New York City. These findings, according to Mount Sinai researchers, could be the first step toward developing new interventions for PTSD.

21 Apr 2014

Stanford researchers identify normal cell type that gives rise to most invasive bladder cancers

A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer, according to researchers at the Stanford University School of Medicine.

21 Apr 2014

Researchers devise new approach to treatment of Alzheimer's disease

A team of researchers from Columbia University Medical Center, Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer's disease involving the so-called retromer protein complex. Retromer plays a vital role in neurons, steering amyloid precursor protein (APP) away from a region of the cell where APP is cleaved, creating the potentially toxic byproduct amyloid-beta, which is thought to contribute to the development of Alzheimer's.

21 Apr 2014

Researchers reveal connection between Down syndrome and acute lymphoblastic leukemia

Although doctors have long known that people with Down syndrome have a heightened risk of developing acute lymphoblastic leukemia (ALL) during childhood, they haven't been able to explain why. Now, a team of Dana-Farber Cancer Institute investigators has uncovered a connection between the two conditions.

21 Apr 2014

Highlights: N.Y. court ends taxi health care fund; Colo. psychotropic drug efforts lag

Until late last week, help seemed close. In 2012, the city's Taxi and Limousine Commission had voted to take six cents on every fare for a fund that would help with exactly these kinds of situations, providing upwards of $300 per week in assistance as soon as a driver could produce a doctor's note.

18 Apr 2014

Scientist receives $1.8M defense grant from Kessler Foundation for spinal cord injury research

Kessler Foundation has been named awardee of a three-year grant for $1.8 million from the Department of Defense Spinal Cord Injury Research Program. Gail Forrest, PT, PhD, is principal investigator for the randomized, double-blinded, controlled, multi-site clinical trial, which will test strategies to improve bone and muscle strength after spinal cord injury. Dr. Forrest is assistant director of Human Performance & Engineering Research at Kessler Foundation.

18 Apr 2014

Research: Spending time online has potential to ward off depression among retirees

Spending time online has the potential to ward off depression among retirees, particularly among those who live alone, according to research published online in The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences.

18 Apr 2014

New research may help scientists develop treatments or vaccines for Dengue fever

Two recent papers by a University of Colorado School of Medicine researcher and colleagues may help scientists develop treatments or vaccines for Dengue fever, West Nile virus, Yellow fever, Japanese encephalitis and other disease-causing flaviviruses.

18 Apr 2014

Researchers identify novel vancomycin-resistant MRSA superbug in Brazil

An international research team led by Cesar A. Arias, M.D., Ph.D., at The University of Texas Health Science Center at Houston has identified a new superbug that caused a bloodstream infection in a Brazilian patient. The report appeared in the April 17 issue of The New England Journal of Medicine.

17 Apr 2014

First MRI scan shows 'brown fat' in living adult can help fight diabetes

The first MRI scan to show 'brown fat' in a living adult could prove to be an essential step towards a new wave of therapies to aid the fight against diabetes and obesity.

17 Apr 2014

Study reveals factors that contribute to eye mobility disorder

Imagine you cannot move your eyes up, and you cannot lift your upper eyelid. You walk through life with your head tilted upward so that your eyes look straight when they are rolled down in the eye socket.

17 Apr 2014

Research sheds new light on the development of HPV-associated cancer

It's long been known that certain strains of human papillomavirus (HPV) cause cancer. Now, researchers at The Ohio State University have determined a new way that HPV might spark cancer development - by disrupting the human DNA sequence with repeating loops when the virus is inserted into host-cell DNA as it replicates.

17 Apr 2014

Medical School News and Research

Researchers uncover novel function of Amyloid Precursor Protein linked to Alzheimer's disease

New genetic evidence strengthens link between role of dietary fats with colon cancer progression

FDA approves molecularly targeted drug as second-line treatment for advanced stomach cancer

New approach may help reduce use of antipsychotics and other psychiatric drugs in dementia patients

Scientists receive federal grant to track how multi-walled carbon nanotubes interact with human cells

Researchers develop simple assay that reveals evolutionary relationships among various tumor sites within patient

Study points to new therapeutic strategy for treating depression

DePuy Synthes CMF announces launch of Patient Specific Plates for Mandible

IV-administered ketamine effective in patients with chronic PTSD

Stanford researchers identify normal cell type that gives rise to most invasive bladder cancers

Researchers devise new approach to treatment of Alzheimer's disease

Researchers reveal connection between Down syndrome and acute lymphoblastic leukemia

Highlights: N.Y. court ends taxi health care fund; Colo. psychotropic drug efforts lag

Scientist receives $1.8M defense grant from Kessler Foundation for spinal cord injury research

Research: Spending time online has potential to ward off depression among retirees

New research may help scientists develop treatments or vaccines for Dengue fever

Researchers identify novel vancomycin-resistant MRSA superbug in Brazil

First MRI scan shows 'brown fat' in living adult can help fight diabetes

Study reveals factors that contribute to eye mobility disorder

Research sheds new light on the development of HPV-associated cancer

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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