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WellPoint research leads to limits on use of Boniva; FDA spars with tobacco company

"WellPoint Inc. (WLP), the largest U.S. managed-care concern by membership, made it harder last year for its members to gain approval for use of the Boniva osteoporosis drug after internal research linked it to higher fracture rates, lower patient compliance and higher total costs of care than two other drugs, a WellPoint executive said Thursday," Dow Jones Newswires/The Wall Street Journal reports.

28 Jun 2010

EDF praises New York State Assembly for passing legislation to reduce sulfur levels in heating oil

Environmental Defense Fund praised the New York State Assembly for passing legislation today to dramatically reduce sulfur levels in the commonly used #2 heating oil sold in the state. The State Senate passed the legislation last week and Governor Paterson is expected to sign it into law.

28 Jun 2010

Researchers discover genetic links to kidney failure, diabetic kidney disease

Researchers at the Translational Genomics Research Institute will make two presentations at this week's 70th Scientific Sessions of the American Diabetes Association, June 25-29, in Orlando, Florida.

28 Jun 2010

Kansas doctor and wife found guilty of prescribing painkillers, causing deaths

"A federal jury Thursday found a Kansas doctor and his wife guilty of conspiring to profit from illegally prescribing painkillers to dozens of patients who later died, in a case highlighting medical treatment of chronic pain sufferers and prescription drug abuse."

28 Jun 2010

Psychotropic medications associated with adverse drug reactions in Danish children: Researchers

Between 1998 and 2007, psychotropic medications were associated with 429 adverse drug reactions in Danish children under the age of 17. Researchers from the University of Copenhagen's Faculty of Pharmaceutical Studies have published an article in the open access journal BMC Research Notes concluding that more than half of the 429 cases were serious and several involved birth defects, such as birth deformities and severe withdrawal syndromes.

25 Jun 2010

Researchers identify a key player in dramatic loss of neurons in mice and fly models

A team of researchers, led by scientists at the University of California, San Diego, have identified a key player in the dramatic loss of neurons in mice and fly models, a discovery that could help illuminate the role of mitochondrial dysfunction in human neurodegenerative disorders, such as Parkinson's disease.

25 Jun 2010

Researchers uncover association between free radical-mediated reactions and progression of SLE

University of Texas Medical Branch researchers have uncovered an association between free radical-mediated reactions and the severity and progression of system lupus erythematosus. Higher levels of oxidative and nitrosative stress markers were found in SLE patients with greater disease activity suggesting a causal relationship. Full findings of the study are available in the July issue of Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology.

25 Jun 2010

PARP inhibitors may be effective in men with prostate cancer due to BRCA2 alteration: Researchers

The way prostate cancer develops in men who have an altered 'breast cancer gene' is the same route by which breast cancer develops in women with the same mutation, reveals a study published in PLoS Genetics today (Thursday).

25 Jun 2010

Specific virus can interact with mutation in host's genes to trigger diseases: Scientists

Scientists have shown that a specific virus can interact with a mutation in the host's genes to trigger disease. The observation may help explain why many people with disease risk genes do not actually develop disease.

25 Jun 2010

Two experimental drugs have potential to restore pumping strength to failing hearts, study finds

We've all experienced the strong heartbeat that accompanies emotions such as fear and rage. But can the body's natural response to these emotions be used to combat heart failure? Results of a study published online today in the journal Circulation Research present a strong case.

25 Jun 2010

News roundup: Judge approves $712 million settlement for 9/11 emergency workers' health problems; Missouri ballot measure on health overhaul challenged

A judge approved a $712 million health settlement for thousands of emergency workers who responded after the Sept. 11 attack, in spite of objections from some who complained that the deal was unfair. Some workers who say they got sick working at the Ground Zero site argued Wednesday that the settlement shortchanged those suffering from certain types of diseases. One of the key factors in how much workers get paid under the settlement, approved by U.S. District Judge Alvin Hellerstein, depends on the type of disease the person contracted.

25 Jun 2010

Tanning protects skin from harmful sun rays

People who remain pale and never tan can blame their distant ancestors for choosing to live in the northern reaches of the globe and those who easily achieve a deep tan can thank their ancestors for living in the subtropical latitudes, according to Penn State anthropologists.

25 Jun 2010

AGTC, Icagen complete agreement for purchase and sale of patent rights

AGTC, a privately held company, and Icagen, Inc. today announced the completion of an agreement for the purchase and sale of certain patent rights between the companies. Icagen is transferring its rights to patents relating to the ion channel gene CNGB3, which has been linked to certain disorders of the eye. Under the terms of the agreement, Icagen has assigned ownership of the patents to AGTC, which intends to use the patented technology for gene therapy as a potential treatment for Achromatopsia, a severe form of daytime blindness.

24 Jun 2010

AVIS donates health research project focuses on cancer biomarkers

The greatest research project on cancer biomarkers is to start in the next months. The new scientific research will open new frontiers in the field of prevention of two most relevant cancer: prostate cancer and ovarian cancer. The research project, which also includes an important prevention programme, is named "AVIS donates health" (AVIS is the Italian most important blood donors association) and is supported by Fondazione Abo - Application of biotechnologies in Oncology, Avis, Lilt (Italiana League for the fight against cancer) and by the three scientific societies of gynecologists and urologists.

24 Jun 2010

First Edition: June 24, 2010

Today's headlines reflect the latest news about action in the Senate regarding the Medicare "doc fix" and Medicaid assistance for states as well as developments across the health care marketkplace.

24 Jun 2010

Increased mortality rates in Bangladesh is associated with arsenic exposure, study finds

Between 33 and 77 million people in Bangladesh have been exposed to arsenic in the drinking water-a catastrophe that the World Health Organization has called "the largest mass poisoning in history." A new study published in the current issue of the medical journal The Lancet provides the most complete and detailed picture to date of the high mortality rates associated with this exposure, which began with the widespread installation of tube wells throughout the country 30 years ago-a measure intended to control water-bourne diseases.

24 Jun 2010

$Phase 1 clinical trial of XMT-1107 initiated in patients with refractory advanced solid tumors$

Phase 1 clinical trial of XMT-1107 initiated in patients with refractory advanced solid tumors

Mersana Therapeutics, a platform-based cancer therapeutics company, today announced that it has initiated a Phase 1 clinical trial to study the safety and pharmacokinetics of XMT-1107 in patients with refractory advanced solid tumors. XMT-1107 is a novel anti-angiogenic fumagillin analog that employs Mersana's Fleximer platform. Mersana's XMT-1001, a conjugate of Fleximer and camptothecin, is currently completing a Phase 1 study.

23 Jun 2010

Gay men and heterosexual women code faces bilaterally: Study

Gay men can recall familiar faces faster and more accurately than their heterosexual counterparts because, like women, they use both sides of their brains, according to a new study by York University researchers.

23 Jun 2010

Diet with high fructose, trans fats lead to fatty liver disease with scar tissue

Scientists at Cincinnati Children's Hospital Medical Center have discovered that a diet with high levels of fructose - levels equivalent to that in high fructose corn syrup - and of trans fats not only increases obesity, but also leads to significant fatty liver disease with scar tissue.

23 Jun 2010

Resveratrol found in red wine neutralizes toxicity of proteins related to Alzheimer's disease: Research

An organic compound found in red wine - resveratrol - has the ability to neutralize the toxic effects of proteins linked to Alzheimer's disease, according to research led by Rensselaer Professor Peter M. Tessier. The findings, published in the May 28 edition of the Journal of Biological Chemistry, are a step toward understanding the large-scale death of brain cells seen in certain neurodegenerative diseases.

23 Jun 2010

X linked News and Research

WellPoint research leads to limits on use of Boniva; FDA spars with tobacco company

EDF praises New York State Assembly for passing legislation to reduce sulfur levels in heating oil

Researchers discover genetic links to kidney failure, diabetic kidney disease

Kansas doctor and wife found guilty of prescribing painkillers, causing deaths

Psychotropic medications associated with adverse drug reactions in Danish children: Researchers

Researchers identify a key player in dramatic loss of neurons in mice and fly models

Researchers uncover association between free radical-mediated reactions and progression of SLE

PARP inhibitors may be effective in men with prostate cancer due to BRCA2 alteration: Researchers

Specific virus can interact with mutation in host's genes to trigger diseases: Scientists

Two experimental drugs have potential to restore pumping strength to failing hearts, study finds

News roundup: Judge approves $712 million settlement for 9/11 emergency workers' health problems; Missouri ballot measure on health overhaul challenged

Tanning protects skin from harmful sun rays

AGTC, Icagen complete agreement for purchase and sale of patent rights

AVIS donates health research project focuses on cancer biomarkers

First Edition: June 24, 2010

Increased mortality rates in Bangladesh is associated with arsenic exposure, study finds

Phase 1 clinical trial of XMT-1107 initiated in patients with refractory advanced solid tumors

Gay men and heterosexual women code faces bilaterally: Study

Diet with high fructose, trans fats lead to fatty liver disease with scar tissue

Resveratrol found in red wine neutralizes toxicity of proteins related to Alzheimer's disease: Research

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