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Study finds communication gap between doctors and parents in management of children's food allergies

When a child has a food allergy, it's critical for pediatricians and allergists to show parents when and how to use an epinephrine auto-injector and to provide a written emergency food allergy action plan for home and school. It is essential in case of a life-threatening reaction.

13 Jan 2016

New discovery may help researchers tackle mitochondrial diseases and age-related diseases

Buck Institute faculty Judith Campisi, PhD, says age researchers need to stop thinking of cellular senescence, now accepted as an important driver of aging, as a single phenotype that stems from genotoxic stress. Research from her lab reveals that cellular senescence, a process whereby cells permanently lose the ability to divide, is also induced by signaling from dysfunctional mitochondria - and that the arrested cells secrete a distinctly different "stew" of biologically active factors in a process unrelated to the damaging free radicals that are created in mitochondria as part of oxygen metabolism.

13 Jan 2016

Preschoolers with poor short-term recall at risk of dropping out of high school

If your toddler is a Forgetful Jones, you might want to help boost his or her brainpower sooner rather than later. New research shows that preschoolers who score lower on a memory task are likely to score higher on a dropout risk scale at the age of 12.

13 Jan 2016

Long-term use of opioids increases risk of new-onset depression

Opioids may cause short-term improvement in mood, but long-term use imposes risk of new-onset depression, a Saint Louis University study shows.

13 Jan 2016

Using statins before and after heart surgery can help reduce cardiac complications, mortality risks

Using statins before and after coronary artery bypass grafting (CABG) surgery can help reduce cardiac complications, such as atrial fibrillation, following surgery and also can reduce the risk of death during and after surgery, according to a review article posted online today by The Annals of Thoracic Surgery.

13 Jan 2016

Estrogen may protect women against flu

The female sex hormone estrogen has anti-viral effects against the influenza A virus, commonly known as the flu, a new study in American Journal of Physiology—Lung Cellular and Molecular Physiology reports.

13 Jan 2016

First patient enrolled in ThromboGenics' Phase II CIRCLE study of ocriplasmin in NPDR patients

ThromboGenics NV, an integrated biopharmaceutical company focused on developing and commercializing innovative treatments for diabetic eye disease, today announces that the first patient has been enrolled in its Phase II CIRCLE study evaluating the efficacy and safety of multiple doses of ocriplasmin in inducing total posterior vitreous detachment (PVD) in patients with non-proliferative diabetic retinopathy (NPDR).

13 Jan 2016

New clinical study reveals previously unknown risk factors linked to keratoconus

A large new study reveals previously unknown risk factors associated with an eye condition that causes serious progressive nearsightedness at a relatively young age.

13 Jan 2016

TSRI scientists receive $2.1 million NIH grant to create new library of drug candidates

Scientists at The Scripps Research Institute have received a grant of more than $2.1 million from the National Institutes of Health's National Institute of General Medical Sciences to create and screen a new library of drug candidates.

13 Jan 2016

Mexican immigrant children's diet different from their mothers'

The diet of Mexican immigrant children in the U.S. is different from what their mothers eat, according to Penn State sociologists, and that may mean kids are trading in the generally healthy diet of their moms for less nutritious American fare.

13 Jan 2016

Selenium supplementation may have positive and negative effects on immune system

A more thorough evaluation of selenium supplementation is needed, to better understand its benefits to our immune system, and the risks.

13 Jan 2016

Researchers reveal secondary structure of Lewy bodies in the brain of Parkinson's disease patients

Lewy bodies had been considered to be a key element of pathogenesis for Parkinson's disease. Although structural analysis for Lewy bodies with an electron microscope had been performed, it had no secondary structural information of proteins, which is important for the development of drugs.

13 Jan 2016

Inflammation associated with elevated glutamate in the brain could guide depression treatments

Psychiatrists investigating depression have been energized in recent years by reports of rapid, successful treatment with drugs that interfere with the brain chemical glutamate, such as the anesthetic ketamine.

13 Jan 2016

CGP3466B compound may effectively treat depression

The compound CGP3466B, already proven nontoxic for people, may effectively and rapidly treat depression, according to results of a study in mice.

13 Jan 2016

Switching to smaller plates could help curb obesity

There are small easy steps that we can take to tackle the burgeoning problem of obesity. One of those solutions is surprisingly simple: use smaller plates.

13 Jan 2016

CPMC study discovers six genes that affect sleep duration

The Coriell Personalized Medicine Collaborative, a research initiative exploring the utility of genetic information in the clinical setting, has published a study and identified six noteworthy genes that affect human sleep duration.

13 Jan 2016

Sedentary behavior associated with poor cardiovascular health, diabetes in people with severe obesity

Sedentary behavior is associated with poor cardiovascular health and diabetes in adults with severe obesity, independent of how much exercise they perform, a University of Pittsburgh Graduate School of Public Health-led study showed for the first time.

13 Jan 2016

High doses of vitamin D may increase risk of falls

According to new research summarized by California Pacific Medical Center Research Institute senior scientist Steven Cummings, MD, and colleagues at the University of California, San Francisco and Harvard Medical School, contrary to common beliefs, relatively high doses of vitamin D may increase the risk of falls.

13 Jan 2016

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

In humans the differentiation of stem cells into hundreds of specialized cell types is vital. Differentiation drives development from fertilized egg to a newborn, and it underlies the continuous replacement of the 5 billion cells that die every hour in an adult. On the downside, mutations in differentiation pathways of different cell types can be drivers of cancers.

13 Jan 2016

Minority and ethnic groups diagnosed with colorectal cancer at younger ages

Colorectal cancer is the third most common form of cancer and the second most common cause of cancer deaths in the United States. The chance of developing colorectal cancer increases with age. Now, a study by University of Missouri School of Medicine researchers shows that minority and ethnic groups are being diagnosed with colorectal cancer at younger ages and more advanced stages than non-Hispanic whites.

12 Jan 2016

Research News and Research

Study finds communication gap between doctors and parents in management of children's food allergies

New discovery may help researchers tackle mitochondrial diseases and age-related diseases

Preschoolers with poor short-term recall at risk of dropping out of high school

Long-term use of opioids increases risk of new-onset depression

Using statins before and after heart surgery can help reduce cardiac complications, mortality risks

Estrogen may protect women against flu

First patient enrolled in ThromboGenics' Phase II CIRCLE study of ocriplasmin in NPDR patients

New clinical study reveals previously unknown risk factors linked to keratoconus

TSRI scientists receive $2.1 million NIH grant to create new library of drug candidates

Mexican immigrant children's diet different from their mothers'

Selenium supplementation may have positive and negative effects on immune system

Researchers reveal secondary structure of Lewy bodies in the brain of Parkinson's disease patients

Inflammation associated with elevated glutamate in the brain could guide depression treatments

CGP3466B compound may effectively treat depression

Switching to smaller plates could help curb obesity

CPMC study discovers six genes that affect sleep duration

Sedentary behavior associated with poor cardiovascular health, diabetes in people with severe obesity

High doses of vitamin D may increase risk of falls

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

Minority and ethnic groups diagnosed with colorectal cancer at younger ages

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