Inflammation News and Research

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X-Chem, Astrazeneca Expand Drug Discovery Collab

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3 Oct 2013

Specialized cells play major role in inflammation that underlies Crohn's disease in small intestine

Scientists have discovered that Crohn's disease, the inflammatory bowel disorder, can originate from specialised intestinal cell type called Paneth cells. As such, they propose that small intestinal Crohn's disease might be a specific disorder of this cell type, providing a possible new target for treatments.

3 Oct 2013

Research: Children with inherited anti-inflammatory defect may have predisposition to lymphoma

New research shows that children with an inherited genetic defect in a critical anti-inflammatory pathway have a genetic predisposition to lymphoma. Results of the study, published online today in Blood, the Journal of the American Society of Hematology (ASH), reveal an important association between the genetic defect, which causes chronic intestinal inflammation and early onset inflammatory bowel disease, and its role in cancer development in infants and children.

3 Oct 2013

NCI explores how erectile dysfunction drugs work to prevent colon cancer

Erectile dysfunction drugs may be able to help prevent or even treat colon cancer, researchers say.

3 Oct 2013

Queen's research to investigate how superbug affects cystic fibrosis patients

Queen's University Belfast is to lead a £139,000 study into the way cystic fibrosis sufferers are affected by a superbug that destroys lung function.

2 Oct 2013

Statin medications pose no threat to short-term memory and may protect against dementia

A review of dozens of studies on the use of statin medications to prevent heart attacks shows that the commonly prescribed drugs pose no threat to short-term memory, and that they may even protect against dementia when taken for more than one year.

2 Oct 2013

Genetic study helps identify obese diabetes patients who are at risk of developing NAFLD

A groundbreaking study of nearly 2,300 extremely obese diabetes patients, led by the Translational Genomics Research Institute, has identified genes associated with unhealthy liver function.

2 Oct 2013

Resveratrol worsens MS-like neuropathology and inflammation, study finds

Resveratrol, a naturally occurring polyphenol compound produced by the skin of red grapes and peanuts, and found in red wine, has been touted as a beneficial supplement due to its anti-inflammatory and antioxidant properties.

1 Oct 2013

Precise value of EXACT in COPD uncertain

EXACT is effective in assessing exacerbations of chronic obstructive pulmonary disease in the outpatient setting, a study shows.

1 Oct 2013

Study shows direct causative link between obesity and risk of pancreatic cancer in mice

Researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC) have found that mice made obese by being given high-calorie, high-fat diets (HFCD) developed abnormally high numbers of lesions known as pancreatic intraepithelial neoplasias (PanINs), which are known to be precursors to pancreas cancer.

1 Oct 2013

IMSGC scientists identify 48 genetic variants influencing risk of developing MS

Scientists of the International Multiple Sclerosis Genetics Consortium (IMSGC) have identified an additional 48 genetic variants influencing the risk of developing multiple sclerosis.

1 Oct 2013

MD Anderson-developed aerosol triggers innate immunity to squelch infections

Research on an aerosol that jump-starts a rapid immune response to stifle viral respiratory infections before they can provoke asthma attacks has earned major funding from the National Institutes of Health.

1 Oct 2013

A*STAR, NSC and NTU to expand skin research in Singapore

Singapore is committing close to S$100 million to skin research, with the announcement of the Skin Research Institute of Singapore. A collaboration between the Agency for Science Technology and Research, National Skin Centre and Nanyang Technological University, the SRIS will harness the expertise of scientists, clinicians and engineers to foster and conduct high impact, inter-disciplinary skin research designed to translate into improved health outcomes and quality of life.

30 Sep 2013

c-Fos oncogene cab be important target for understanding and treatment of cancer

The c-Fos oncogene has traditionally been linked to cellular activities related to cancer, such as cell division, differentiation-conversion from one cell type to another-or survival. Any alteration of these activities can set off the development of tumours, which has made c-Fos an important target for the understanding and treatment of cancer.

29 Sep 2013

Research opens up possibility for new treatment approaches for motor neurone disease

New research from the University of Sheffield could offer solutions into slowing down the progression of motor neurone disease.

28 Sep 2013

Psoriasis and the nervous system: an interview with Dr Nicole Ward, Case Western Reserve University

The prevalence of skin disease exceeds that of obesity, hypertension or cancer. One in three individuals in the United States suffers with a skin disease, with ~2-3% of the American population suffering from psoriasis.

27 Sep 2013

Intestinal mucus potentially improves life of people suffering from inflammatory bowel disease

Researchers at Institut Hospital del Mar d'Investigacions M-diques (IMIM) in Barcelona, in collaboration with the Icahn School of Medicine at Mount Sinai in New York and other U.S. Institutions, have found that intestinal mucus not only acts as a physical barrier against commensal bacteria and dietary antigens, but also prevents the onset of inflammatory reactions against these agents.

27 Sep 2013

Childhood abuse, lack of parental affection may increase health risk in adulthood

The effects of childhood abuse and lack of parental affection can last a lifetime, taking a toll both emotionally and physically.

27 Sep 2013

TSRI scientists discover process by which special immune cells in skin help heal wounds

Scientists at The Scripps Research Institute (TSRI) have discovered an important process by which special immune cells in the skin help heal wounds. They found that these skin-resident immune cells function as "first responders" to skin injuries in part by producing the molecule known as interleukin-17A (IL-17A), which wards off infection and promotes wound healing.

27 Sep 2013

Use of feeding tubes in OPC cancer patients treated with IMPT decreased by 50%

A new study from researchers at The University of Texas MD Anderson Proton Therapy Center found that the use of feeding tubes in oropharyngeal carcinoma cancer patients treated with intensity modulated proton therapy decreased by more than 50 percent compared to patients treated with intensity modulated radiation therapy.

26 Sep 2013

Inflammation News and Research

X-Chem, Astrazeneca Expand Drug Discovery Collab

Specialized cells play major role in inflammation that underlies Crohn's disease in small intestine

Research: Children with inherited anti-inflammatory defect may have predisposition to lymphoma

NCI explores how erectile dysfunction drugs work to prevent colon cancer

Queen's research to investigate how superbug affects cystic fibrosis patients

Statin medications pose no threat to short-term memory and may protect against dementia

Genetic study helps identify obese diabetes patients who are at risk of developing NAFLD

Resveratrol worsens MS-like neuropathology and inflammation, study finds

Precise value of EXACT in COPD uncertain

Study shows direct causative link between obesity and risk of pancreatic cancer in mice

IMSGC scientists identify 48 genetic variants influencing risk of developing MS

MD Anderson-developed aerosol triggers innate immunity to squelch infections

A*STAR, NSC and NTU to expand skin research in Singapore

c-Fos oncogene cab be important target for understanding and treatment of cancer

Research opens up possibility for new treatment approaches for motor neurone disease

Psoriasis and the nervous system: an interview with Dr Nicole Ward, Case Western Reserve University

Intestinal mucus potentially improves life of people suffering from inflammatory bowel disease

Childhood abuse, lack of parental affection may increase health risk in adulthood

TSRI scientists discover process by which special immune cells in skin help heal wounds

Use of feeding tubes in OPC cancer patients treated with IMPT decreased by 50%

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