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Researchers use endocytic pathways to sort out NSCLC lines into two distinct clusters

In the Age of Personalized Medicine, we've learned that one size doesn't fit all, least of all in cancer. Cancer is a disease of your cells, and sorting out your cancer from all others is a daunting challenge but one that cancer cell biologists are furiously pursuing. They are examining every aspect of cell function and cell structure, looking for clusters of phenotypes that could label a patient's cancer so precisely that it could be linked to therapies proven effective against just that type.

12 Dec 2015

Exposure to violence in Mexico negatively affects mental health of children

Children who lived in Juarez, Mexico — once dubbed the murder capital of the world — in 2010 have high levels of behavioral and emotional problems, according to new research by Texas Tech University Health Sciences Center El Paso.

12 Dec 2015

New research sheds light on outcomes for patients with thyroid cancer

Thyroid cancer survivors report poor quality of life after diagnosis and treatment compared with other patients who are diagnosed with more lethal cancers, according to new research from the University of Chicago Medicine.

12 Dec 2015

Workplace intervention can help prevent diabetes

For people who already have high blood sugar, preventing diabetes could amount to just another day at the office.

12 Dec 2015

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

The U.S. Food and Drug Administration today approved Alecensa (alectinib) to treat people with advanced (metastatic) ALK-positive non-small cell lung cancer (NSCLC) whose disease has worsened after, or who could not tolerate treatment with, another therapy called Xalkori (crizotinib).

11 Dec 2015

Nearly half of Muslim Americans face discrimination in health care workplace

While many studies have examined the impact of bias based on race, gender or sexual orientation, religious discrimination in the health care workplace has received little research attention. A new study funded by the John Templeton Foundation and conducted at the University of Chicago finds that for Muslim Americans, even those in one the nation's most highly regarded professions, encounter a less-than-inclusive and welcoming work environment during their career.

11 Dec 2015

Right atrial function could be prognostic in PAH

Right atrial function is impaired in patients with pulmonary arterial hypertension and may indicate right ventricular overload and failure, research suggests.

11 Dec 2015

Slow walking speed may herald Alzheimer’s disease

A slow walking speed in elderly people is associated with the presence of β-amyloid in their brains, research shows.

11 Dec 2015

Androgen deprivation therapy elevates Alzheimer’s risk

US researchers find that androgen deprivation therapy increases the risk of Alzheimer’s disease in men with prostate cancer, with the risk rising with greater duration of therapy.

11 Dec 2015

Biogen begins ISIS-SOD1 Rx Phase 1/2 clinical study in patients with amyotrophic lateral sclerosis

Isis Pharmaceuticals, Inc. today announced that its partner, Biogen, has initiated a Phase 1/2 clinical study of ISIS-SOD1 Rx (BIIB067) in patients with amyotrophic lateral sclerosis (ALS).

11 Dec 2015

Sangamo presents Phase 2 data from two ongoing clinical trials of SB-728-T for treatment of HIV/AIDS

Sangamo BioSciences, Inc., the leader in therapeutic genome editing, announced the presentation of Phase 2 data from two of the Company's ongoing clinical trials (SB-728-1101 Cohort 3* and SB-728-mR-1401) of SB-728-T, which is being developed for the functional control of HIV/AIDS.

11 Dec 2015

Benefits of early dementia diagnosis may lead to challenging issues, new study shows

A new epidemiologic study showed that patients with early stage dementia, who had been referred to a specialist, have twice the risk of institutionalization compared to those who are not, according to a research study published in the Journal of Alzheimer's Disease this month.

11 Dec 2015

Researchers find new method to create uniform standards in search for cancer-relevant mutations

Oncologists are increasingly using information obtained from investigations of the tumor genome in order to find individualized therapies for patients. They specifically search the hereditary information of cancer cells for mutations that drive malignant growth. By now, targeted drugs against many of these cancer-typical cellular alterations have become available.

11 Dec 2015

Findings may lead to new treatment strategy for phobia

A new study published in the latest issue of Biological Psychiatry reports the successful and instant reduction of fear in spider-fearful participants following a 2-minute exposure combined with a single dose of a regular pharmacological treatment.

11 Dec 2015

Adjuvant chemotherapy not beneficial for patients with luminal A subtype of breast cancer

Premenopausal women whose invasive breast cancers were of the luminal A subtype had comparable 10-year disease-free survival rates regardless of whether or not they received adjuvant chemotherapy, according to data from the phase III DBCG77B clinical trial presented at the 2015 San Antonio Breast Cancer Symposium, held Dec. 8-12.

11 Dec 2015

Pathologic complete response after presurgery chemotherapy increases overall survival for TNBC patients

Patients with stage 2 or stage 3 triple-negative breast cancer (TNBC) who had a pathologic complete response (pCR) after presurgery chemotherapy had increased event-free and overall survival compared with those who had more than minimal residual invasive disease at surgery following presurgery chemotherapy, according to results from the randomized phase II CALGB/Alliance 40603 clinical trial presented at the 2015 San Antonio Breast Cancer Symposium, held Dec. 8-12.

11 Dec 2015

Capecitabine increases disease-free survival for HER2-negative breast cancer patients

Treatment with the chemotherapy agent capecitabine increased disease-free survival for women with HER2-negative breast cancer that was not eliminated by presurgery chemotherapy, according to results from the phase III CREATE-X clinical trial presented at the 2015 San Antonio Breast Cancer Symposium, held Dec. 8-12.

11 Dec 2015

UC San Diego biologists develop a method to screen natural products for new antibiotics

Biologists at UC San Diego have found that a method they developed to identify and characterize new antibiotics can be employed to screen natural products quickly for compounds capable of controlling antibiotic resistant bacteria.

11 Dec 2015

UC San Diego's Comprehensive Stroke Center receives Gold Plus Award

When someone experiences a major stroke, almost two million nerve cells in the brain die each minute, emphasizing the need for rapid treatment. Stroke patients who receive life-saving interventions more quickly have a higher chance of recovery. A recent data analysis showed the Comprehensive Stroke Center at UC San Diego Medical Center exceeded national average treatment times, and as a result, has received a "Get With The Guidelines-Stroke Gold Plus Quality Achievement Award" from The American Heart Association and American Stroke Association.

11 Dec 2015

Advanced thyroid cancer rates above national average in several parts of California

A team of UCLA researchers found that there are several parts of California where, in a high percentage of people with thyroid cancer, the disease is already at an advanced stage by the time it is diagnosed.

11 Dec 2015

Research News and Research

Researchers use endocytic pathways to sort out NSCLC lines into two distinct clusters

Exposure to violence in Mexico negatively affects mental health of children

New research sheds light on outcomes for patients with thyroid cancer

Workplace intervention can help prevent diabetes

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

Nearly half of Muslim Americans face discrimination in health care workplace

Right atrial function could be prognostic in PAH

Slow walking speed may herald Alzheimer’s disease

Androgen deprivation therapy elevates Alzheimer’s risk

Biogen begins ISIS-SOD1 Rx Phase 1/2 clinical study in patients with amyotrophic lateral sclerosis

Sangamo presents Phase 2 data from two ongoing clinical trials of SB-728-T for treatment of HIV/AIDS

Benefits of early dementia diagnosis may lead to challenging issues, new study shows

Researchers find new method to create uniform standards in search for cancer-relevant mutations

Findings may lead to new treatment strategy for phobia

Adjuvant chemotherapy not beneficial for patients with luminal A subtype of breast cancer

Pathologic complete response after presurgery chemotherapy increases overall survival for TNBC patients

Capecitabine increases disease-free survival for HER2-negative breast cancer patients

UC San Diego biologists develop a method to screen natural products for new antibiotics

UC San Diego's Comprehensive Stroke Center receives Gold Plus Award

Advanced thyroid cancer rates above national average in several parts of California

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