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Scientists show how absence of microbiota has remarkable effect against obesity

In the past few years, research on gut microbiota (that is, all microorganisms, mainly bacteria, inhabiting our gut) has started to unravel its tremendous role in our body, and how it symbiotically affects the functioning of our organs. In particular, microbiota has also an impact on the way calories are absorbed and how fat cells develop.

17 Nov 2015

Researchers identify molecular patterns that dominate gene expression in the human brain

The human brain may be the most complex piece of organized matter in the known universe, but Allen Institute researchers have begun to unravel the genetic code underlying its function. Research published this month in Nature Neuroscience identified a surprisingly small set of molecular patterns that dominate gene expression in the human brain and appear to be common to all individuals, providing key insights into the core of the genetic code that makes our brains distinctly human.

17 Nov 2015

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells.

17 Nov 2015

CRI scientists identify emergency blood-formation system inside the body

Scientists at the Children's Medical Center Research Institute at UT Southwestern have determined how the body responds during times of emergency when it needs more blood cells. In a study published in Nature, researchers report that when tissue damage occurs, in times of excessive bleeding, or during pregnancy, a secondary, emergency blood-formation system is activated in the spleen.

17 Nov 2015

Overweight men also experience interpersonal discrimination just like overweight women

Men who are overweight are just as likely as overweight women to experience interpersonal discrimination when applying for a job or shopping at retail stores, according to new research from Rice University and the University of North Carolina, Charlotte.

17 Nov 2015

Researchers identify new target for novel immune-oncology treatments

By studying a type of immune cells, a team of researchers at the IRCM led by André Veillette, MD, identified the mechanism of action for a new target for novel immune-oncology treatments. Their discovery is published today in the print edition of the scientific journal the Journal of Experimental Medicine.

17 Nov 2015

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

University of Cincinnati researchers have discovered the negative impact a high fat diet has on red blood cells and how these cells, in turn, promote the development of cardiovascular disease.

17 Nov 2015

Drug prevents onset of cognitive and cellular effects in mouse model of Alzheimer’s disease

In a novel animal study design that mimicked human clinical trials, researchers at University of California, San Diego School of Medicine report that long-term treatment using a small molecule drug that reduces activity of the brain's stress circuitry significantly reduces Alzheimer's disease (AD) neuropathology and prevents onset of cognitive impairment in a mouse model of the neurodegenerative condition.

17 Nov 2015

New analysis points to use of e-cigarettes as quitting aid among U.S. adults

Adding to a growing body of research on patterns of e-cigarette use, researchers from Rutgers School of Public Health and the Steven A. Schroeder Institute for Tobacco Research and Policy Studies at Truth Initiative have found evidence that among U.S. adults, some recent cigarette quitters may have done so with the assistance of electronic cigarettes.

17 Nov 2015

IASLC commends FDA's decision to grant accelerated approval for new lung cancer therapy

The International Association for the Study of Lung Cancer commends the U.S. Food and Drug Administration's (FDA) decision to grant accelerated approval for osimertinib (Tagrisso), an oral medication for advanced non-small cell lung cancer (NSCLC) patients with a specific epidermal growth factor receptor (EGFR) mutation (T790M) and following progression after previous EGFR inhibitor therapies.

17 Nov 2015

Tobacco use continues to be a top threat to health and economic well-being of people in China

Efforts over the past seven years to reduce tobacco use in China have been strikingly ineffective and leave tobacco use a top threat to the health and economic well-being of the world's largest country, according to research findings by the University of Waterloo's International Tobacco Control Policy Evaluation Project (ITC Project).

17 Nov 2015

Improved gene therapy treatment shows promise in mice with cystic fibrosis

An improved gene therapy treatment can cure mice with cystic fibrosis (CF). Cell cultures from CF patients, too, respond well to the treatment. Those are the encouraging results of a study presented by the Laboratory for Molecular Virology and Gene Therapy at KU Leuven, Belgium.

17 Nov 2015

FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

Today the U.S. Food and Drug Administration granted accelerated approval for Darzalex (daratumumab) to treat patients with multiple myeloma who have received at least three prior treatments. Darzalex is the first monoclonal antibody approved for treating multiple myeloma.

17 Nov 2015

Helmholtz Centre for Infection Research scientists identify promising antitumor agent

Support comes out of the ground: Scientists from the Helmholtz Centre for Infection Research in Germany have identified a terrestrial myxobacterium as a promising source for the bengamide class of natural products, which were originally thought to be secondary metabolites of marine sponges only.

17 Nov 2015

New cancer control interventions may decrease cancer burden in low- and middle-income countries

In low-income and middle-income countries (LMICs), where 5.5 million of the world’s 8 million cancer deaths occur each year, most people with cancer have little or no access to treatment and many die in severe pain for lack of inexpensive opioid pain medicine.

17 Nov 2015

MIPT researchers patent graphene biosensors that may accelerate development of novel drugs

The US Patent Office has recently published the patent application (no. US 2015/0301039), which was filed by the MIPT in May this year and is titled Biological Sensor and a Method of the Production of Biological Sensor. In Russia, this development is already protected by the patent No. 2527699 with a priority date of February 20, 2013. The key feature of the sensor is the use of a linking layer for biomolecule immobilization comprising a thin film of graphene or graphene oxide.

17 Nov 2015

Corning signs agreement to become global distributor for popular BioCision products

Corning Incorporated and BioCision, LLC today announced an agreement that will enable laboratories around the world to further standardize and simplify key steps in their cell culture workflow.

17 Nov 2015

Treating insomnia through a CBT device? An interview with Dr Ebrahim

Insomnia refers to a clinical condition that is characterised by one or more of the following – difficulty initiating sleep and/or maintaining sleep and/or waking up too early AND associated with symptoms the next day such as sleepiness, lethargy, loss of concentration.

16 Nov 2015

MedUni Vienna researchers discover genetic cause of a rare disease

Researchers at MedUni Vienna have discovered the genetic cause of a rare disease characterized by life-threatening "liver crises" in early childhood and subsequent manifestation of neurological symptoms, such as neuropathy and ataxia (a movement disorder), when they reach school age.

15 Nov 2015

Research collaboration aims to develop new drug for slow-healing chronic wounds

The biotech company Omnio based in Swedish Umeå, and led by researcher Tor Ny at Umeå University, launches a research collaboration with the Canadian pharmaceutical company ProMetic to develop a new drug for slow-healing chronic wounds. The collaboration includes funding for clinical studies of a drug based on the blood plasma protein plasminogen.

15 Nov 2015

Research News and Research

Scientists show how absence of microbiota has remarkable effect against obesity

Researchers identify molecular patterns that dominate gene expression in the human brain

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

CRI scientists identify emergency blood-formation system inside the body

Overweight men also experience interpersonal discrimination just like overweight women

Researchers identify new target for novel immune-oncology treatments

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

Drug prevents onset of cognitive and cellular effects in mouse model of Alzheimer’s disease

New analysis points to use of e-cigarettes as quitting aid among U.S. adults

IASLC commends FDA's decision to grant accelerated approval for new lung cancer therapy

Tobacco use continues to be a top threat to health and economic well-being of people in China

Improved gene therapy treatment shows promise in mice with cystic fibrosis

FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

Helmholtz Centre for Infection Research scientists identify promising antitumor agent

New cancer control interventions may decrease cancer burden in low- and middle-income countries

MIPT researchers patent graphene biosensors that may accelerate development of novel drugs

Corning signs agreement to become global distributor for popular BioCision products

Treating insomnia through a CBT device? An interview with Dr Ebrahim

MedUni Vienna researchers discover genetic cause of a rare disease

Research collaboration aims to develop new drug for slow-healing chronic wounds

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