Antimicrobial Resistance News and Research

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Viewpoints: heath insurance and mortality; newly insured vs. previously insured on marketplaces

The connection between health insurance and mortality is really hard to pin down, even if insurance truly has strong protective effects. The uninsured in America are mainly non-elderly adults.

13 May 2014

Long-term use of drug combination reduces risk of recurrent urinary tract infection in children

Long-term use of a drug combination reduces the risk of recurrent urinary tract infection by up to 80 percent in children with the urinary condition vesicoureteral reflux compared to placebo, according to research funded by the National Institutes of Health.

5 May 2014

Cubist submits ceftolozane/tazobactam NDA for treatment of cUTI and cIAI

Cubist Pharmaceuticals, Inc. today announced that it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration for approval of its investigational antibiotic ceftolozane/tazobactam for the treatment of Complicated Urinary Tract Infections (cUTI) and Complicated Intra-Abdominal Infections (cIAI).

21 Apr 2014

Researchers identify novel vancomycin-resistant MRSA superbug in Brazil

An international research team led by Cesar A. Arias, M.D., Ph.D., at The University of Texas Health Science Center at Houston has identified a new superbug that caused a bloodstream infection in a Brazilian patient. The report appeared in the April 17 issue of The New England Journal of Medicine.

17 Apr 2014

JPIAMR outlines steps to minimise antimicrobial resistance

Antibiotics have saved millions of lives from once deadly infectious diseases. But, misuse of antibiotics and other antimicrobials in humans and animals has led to bacteria evolving resistance.

3 Apr 2014

Emergence of community-acquired infections due to ESBL-producing bacteria on the rise

The emergence of community-acquired infections, such as urinary tract infections (UTI), due to strains resistant to common antibiotics are on the rise, according to Rhode Island Hospital researchers. The study is published online in the journal Antimicrobial Resistance and Infection Control.

26 Mar 2014

New research commissioned to create infection control strategy for AMR and antibiotic usage

It is the health system’s nightmare, bubbling just below the surface of our hospitals. Infections are becoming more and more resistant to antibiotics, while secondary infection rates during hospital stays continue to rise.

18 Mar 2014

S. pneumoniae thrives in human saliva

Streptococcus pneumoniae is able to survive and thrive in human saliva, Dutch researchers have shown.

17 Mar 2014

Addressing antibiotic resistance: an interview with Professor Otto Cars, Uppsala University, Sweden

Antibiotic resistance is a consequence of antibiotic use. Bacteria adapt to the threat of antibiotics using mechanisms to overcome the drug. These bacteria, which we call resistant bacteria, then survive.

3 Feb 2014

JHI releases epic3 guidelines on infection prevention for healthcare professionals

The Journal of Hospital Infection has just released the awaited epic3 guidelines on infection prevention and control for a range of healthcare professionals. They are freely available online on ScienceDirect and on the journal's website.

16 Dec 2013

JHI released epic3 guidelines on infection prevention and control for range of healthcare professionals

The Journal of Hospital Infection (JHI) has just released the awaited epic3 guidelines on infection prevention and control for a range of healthcare professionals. They are freely available online on ScienceDirect and on the journal's website.

13 Dec 2013

Rapid DNA biochip tests for screening disease-causing bacteria

Patients affected by a bacterial infection can usually be treated with an antibiotic. But sometimes a resistant bacterial strain is causing the infection. In a hospital setting, doctors ideally want to know if they are dealing with such bacteria and which drugs they should choose. But if the doctor runs a test it can take days to get a result. Now, a European project is paving the way for much more rapid tests using DNA biochips. The aim is to rapidly screen disease-causing bacteria using a microarray to spot which resistant genes are present in bacteria.

20 Nov 2013

TAILORED-Treatment project to increase effectiveness of antibiotics receives EU funding

The European Union has funded a 4 year project called TAILORED-Treatment with € 6.000.000,-. The main goal of TAILORED -Treatment is to establish a strategy that can be used to increase the effectiveness of antibiotic treatment, reduce any potential side-effects of therapy, and help limit the emergence of antimicrobial resistance in hospitalized children and adults. The project will be coordinated by Erasmus MC, Rotterdam, the Netherlands.

14 Nov 2013

Polyphor, Roche agree to develop and commercialize antibiotic for bacterial infections

Polyphor Ltd, a privately held pharmaceutical company, and Roche announced today that they have entered into an exclusive worldwide license agreement to develop and commercialize Polyphor's investigational macrocycle antibiotic, POL7080, for patients suffering from bacterial infections caused by Pseudomonas aeruginosa.

4 Nov 2013

Queen's University is lead partner in £6M global research program to develop new ways to treat CF

Queen's University Belfast is a lead partner in a new -6 million (euro) global research programme to develop new ways to treat Cystic Fibrosis.

30 Oct 2013

WHO report underlines need for quantum leap in TB care and control

Tuberculosis treatment has saved the lives of more than 22 million people, according to the WHO Global tuberculosis report 2013 published today. The report also reveals that the number of people ill with tuberculosis fell in 2012 to 8.6 million, with global TB deaths also decreasing to 1.3 million.

23 Oct 2013

UTHealth professor receives Oswald Avery Award for Early Achievement from IDSA

Cesar Arias, M.D., Ph.D., associate professor in the Division of Infectious Diseases at The University of Texas Health Science Center at Houston Medical School, was bestowed the Oswald Avery Award for Early Achievement from the Infectious Diseases Society of America.

12 Oct 2013

Researchers re-invented class of popular antimicrobial drugs by altering their chemical structures

By tinkering with their chemical structures, researchers at the University of California, San Diego School of Medicine have essentially re-invented a class of popular antimicrobial drugs, restoring and in some cases, expanding or improving, their effectiveness against drug-resistant pathogens in animal models.

8 Oct 2013

Incidence of MRSA bacterial infection increases among Danes

In 2012, 1,556 Danes were found positive with methicillin-resistant staphylococci - MRSA. This represents an increase of 20% from 2011. In fact, the total number of cases has almost doubled since 2009. MRSA bacteria are resistant to antimicrobial agents that are essential for treatment of treating life-threatening infections in humans.

19 Sep 2013

High exposure to swine manure in crop fields linked with increased risk of MRSA, soft-tissue infection

High exposure to swine manure spread in crop fields and proximity to high-density swine livestock operations appear to be associated with increased risk of methicillin-resistant Staphylococcus aureus (MRSA) and skin and soft-tissue infection in humans, according to a study published by JAMA Internal Medicine, a JAMA Network publication.

17 Sep 2013