Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

'Senolytic' therapy blunts liver tumor progression in animal models

"Senotherapy," a treatment that uses small molecule drugs to target "senescent" cells, or those cells that no longer undergo cell division, blunts liver tumor progression in animal models according to new research from a team led by Celeste Simon, Ph.D., a professor of Cell and Developmental Biology in the Perelman School of Medicine at the University of Pennsylvania and scientific director of the Abramson Family Cancer Research Institute.

20 May 2020

Study could help identify more targeted treatments for ovarian cancer

The rogue cellular engine that drives a majority of ovarian cancers remains frustratingly difficult to disable. A new study comparing cancerous tissue with normal fallopian tube samples advances important insights about this machinery and confirms biological hallmarks of survival.

20 May 2020

People with Hepatitis D have up to three times the risk of developing fatal liver cancer

Of all the hepatitis viruses, D is the most poorly known. This small virus, which can only infect people already infected with Hepatitis B, has so far been little studied.

18 May 2020

People infected with hepatitis D are more prone to hepatocellular carcinoma

Of all the hepatitis viruses, D is the most poorly known.This small virus, which can only infect people already infected with Hepatitis B, has so far been little studied.

18 May 2020

New treatment improves survival for people with common liver cancer

For the first time in over a decade, scientists have identified a first-line treatment that significantly improves survival for people with hepatocellular carcinoma, the most common type of liver cancer.

13 May 2020

Trial E3311: Less intense treatment for HPV+ oropharynx cancer shows positive results

The final results of the randomized phase two trial E3311 will be presented at the American Society of Clinical Oncology annual meeting, to occur virtually from May 29-31.

13 May 2020

Simple saliva test detects early throat cancer

A simple saliva test developed by QUT biomedical scientists has detected early throat cancer in a person who had no symptom and no clinical signs of cancer.

12 May 2020

Patients with aggressive form of skin cancer can benefit from new type of immunotherapy

In what is believed to be a first-of-its-kind study to evaluate the safety of a type of immunotherapy before surgery in patients with an aggressive form of skin cancer, researchers report that the treatment eliminated pathologic evidence of cancer in nearly half of the study participants undergoing surgery.

27 Apr 2020

Scientists find gene signature for poor response to standard therapy in rare uterine cancer

Women who don't survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

22 Apr 2020

Radiation therapy plays a crucial role in management of OPSCC

HPV-negative UM-SCC4 with and without transfection of HPV E6 oncoprotein, HPV-negative UPCI-SCC-089, and HPV-positive UPCI-SCC-099 cell lines were used in this study.

22 Apr 2020

A new, potential treatment for nonalcoholic steatohepatitis with fibrosis

In the 2020 April 21 issue of Journal of Hepatology, a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that a new insight into the pathophysiology of human nonalcoholic steatohepatitis (NASH) with fibrosis and suggested a possibility of the new therapy using cytoglobin (CYGB) inducer for clinical application.

21 Apr 2020

Machine learning helps researchers to distinguish a rare subtype of kidney cancer

Putting together research for publication can be a challenging and time-consuming process, heightened even further because of the current COVID-19 situation, during which non-essential labs have been hibernated and many researchers are now working separately and remotely, instead of collaborating within the same space.

21 Apr 2020

A new combinatorial therapy for treatment of liver cancer

In the latest issue of Molecular Therapy, Skoltech and MIT researchers have published a new combinatorial therapy for the treatment of liver cancer.

20 Apr 2020

Analyzing structure of the nipple to understand and fight breast cancer

Nipple-sparing mastectomy is gaining ground as a treatment or preventive measure for breast cancer, given the understandable desire among patients to preserve natural appearance as much as possible.

16 Apr 2020

Drug improves effectiveness of chemotherapy in ovarian cancer patients

An international research team, led by scientists from Mater Research - The University of Queensland, have discovered they can overcome chemotherapy resistance in an ovarian cancer subtype by using low doses of a drug which slows cell growth.

16 Apr 2020

High-resolution imaging with elastography could accurately spot breast cancer in surgical margins

A high-resolution, three-dimensional imaging technique, when combined with quantitative measurement of tissue elasticity, could accurately detect cancer within the resected margins of surgical specimens taken from patients undergoing breast-conserving surgery.

15 Apr 2020

Molecular pathway that controls immunosuppression in tumors identified

An active immune system plays an important role in stopping cancer progression by identifying tumor cells and targeting them for destruction. Any deviation in the normal activities of the immune system could lead to accelerated tumor growth.

14 Apr 2020

Voluntary exercise could help prevent liver cancer, study shows

Liver cancer is the fourth most common cause of cancer death worldwide and is growing rapidly due to the "diabesity pandemic."

14 Apr 2020

Where cancers spread can give specific insights on disease traits

Kidney cancers that metastasize to the pancreas have a fundamentally different biology from those that metastasize elsewhere, with characteristics that can influence successful treatment, a study led by investigators with the UT Southwestern Kidney Cancer Program suggests.

12 Apr 2020

Visualizing 3D microanatomy of human nipple to understand and fight breast cancer

Nipple-sparing mastectomy is gaining ground as a treatment or preventive measure for breast cancer, given the understandable desire among patients to preserve natural appearance as much as possible. But the precise risk of preserving the nipple is not known as the cancer can spread along mammary ducts and to the nipple.

8 Apr 2020