Next generation sequencing NGS News and Research

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Medicinal Genomics sequences entire genomes of two therapeutic Cannabis strains

Medicinal Genomics, a private company headquartered in Marblehead, Mass., USA and the Netherlands, announced today that it has sequenced the entire genomes of Cannabis sativa and Cannabis indica, representing two strains of the therapeutic plant.

19 Aug 2011

TrovaGene regains ownership of worldwide rights to transrenal technology

TrovaGene, Inc., a developer of transrenal molecular diagnostics, confirmed today that it regained ownership of its worldwide rights and control over its patent estate for transrenal technology for non-invasive prenatal applications and cancer through the termination of a license agreement between TrovaGene and Sequenom, Inc.

10 Aug 2011

Affymetrix announces commercialization of next-generation human transcriptome array

Affymetrix, Inc. today announced commercialization of the next-generation human transcriptome array demonstrated by Stanford University researchers to be superior to mRNA sequencing (RNA-Seq) in gene expression profiling studies.

8 Aug 2011

Illumina and University of Oxford collaborate to sequence whole genomes

Illumina, Inc. today announced it will collaborate with the University of Oxford to sequence the whole genomes of 500 individuals afflicted with a range of life-threatening diseases that pose major challenges in diagnosis, treatment, and care. Illumina HiSeq™ 2000 systems will be used to generate sequence data for the 500 genomes.

From Illumina, Inc. 3 Aug 2011

Mitochondrial genome undergoes random reorganisation during reprogramming

Induced pluripotent stem cells (iPS cells) are truly talented multi-taskers. They can reproduce almost all cell types and thus offer great hope in the fight against diseases like Alzheimer's and Parkinson's. However, it would appear that their use is not entirely without risk: during the reprogramming of body cells into iPS cells, disease-causing mutations can creep into the genetic material.

28 Jul 2011

New DNA sequencer will provide deeper insight into gene regulation

The Berlin Institute for Medical Systems Biology (BIMSB) of the Max Delbr-ck Center for Molecular Medicine (MDC) in Berlin, Germany, will be the first academic research institution in Continental Europe to acquire a novel DNA sequencer enabling the sequencing of single DNA molecules in real time.

16 Jul 2011

Researchers discover new gene linked to intellectual disability

A gene linked to intellectual disability was found in a study involving the Centre for Addiction and Mental Health (CAMH) - a discovery that was greatly accelerated by international collaboration and new genetic sequencing technology, which is now being used at CAMH.

15 Jul 2011

People with long term debilitating physical illness demonstrate mental resilience

People who have a long term debilitating physical illness demonstrate mental resilience according to Understanding Society, the world's largest longitudinal household study. The first findings reveal that people diagnosed with cancer, diabetes, respiratory or cardiovascular disease report similar mental health scores to those without physical illness.

11 Jul 2011

Ion Torrent ships three next-generation sequencers

Ion Torrent, a unit of Life Technologies Corporation, today announced that it is shipping its new 100 Mb Ion 316 chip, which has tenfold more throughput than the original Ion 314 chip, and that its 1 Gb Ion 318 chip will be available in the fourth quarter.

11 Jul 2011

BGI, Covaris partner to provide next generation sequencing technology

BGI and Covaris, Inc. today announced a deal that will integrate Covaris' Adaptive Focused Acoustics AFA DNA shearing technology across several BGI laboratories in China.

11 Jul 2011

Isogenica opens new automation facility

Isogenica Ltd today announced the opening of a new automation facility at their current location, Chesterford Research Park.

11 Jul 2011

Extensive genomic, transcriptional diversity identified through massively parallel DNA and RNA sequencing

In a paper published in the online edition of Nature Genetics on July 3, 2011, sequencing specialists at Axeq Technologies, and scientists from Macrogen Inc., Genomic Medicine Institute at Seoul National University, Psoma Therapeutics Inc., Brigham and Women's Hospital and Harvard Medical School reported the discovery of a wide range of novel genetic variants based on the deep sequencing of 18 genomes and 17 transcriptomes of unrelated Korean individuals.

8 Jul 2011

Review of non-smoker patient with lung cancer to be presented at IASLC conference

A first-of-its-kind study of a patient with lung cancer who never smoked will be presented today by TGen and the Virginia G. Piper Cancer Center at Scottsdale Healthcare at the 14th World Conference on Lung Cancer, July 3-7 in Amsterdam.

6 Jul 2011

Genetic mutations in abnormal bone marrow can predict mortality of MDS patients

For patients with myelodysplastic syndromes (MDS), choosing the appropriate treatment depends heavily on the prognosis. Those patients at the highest risk of dying from their disease are typically offered the most aggressive therapies, while patients at lower risk could live several years with MDS, needing only supportive care or other relatively side-effect free treatments.

1 Jul 2011

Start of clinical validation study of Down’s syndrome diagnostic test

In conjunction with several Central European prenatal centers, scientists at GATC Biotech AG and LifeCodexx AG have begun the clinical validation study of a non-invasive, prenatal diagnostic test based on next generation sequencing.

28 Jun 2011

Biolauncher, Isogenica and Cresset enter joint venture to develop drug discovery platform

Isogenica Ltd today announced a collaborative joint venture with Biolauncher Ltd and Cresset Biomolecular Discovery Ltd to develop an innovative end-to-end therapeutic discovery platform.

28 Jun 2011

Gene Codes releases Sequencher 5.0

Gene Codes Corporation announces the release of Sequencher 5.0. It incorporates new DNA sequence data alignment algorithms with SNP and methylation analysis for next-generation DNA sequence data. Performance for assembly and alignment of sequences and contigs is hundreds of times faster.

28 Jun 2011

Transgenomic introduces Nuclear Mitome Test for diagnosis of mitochondrial disorders

Transgenomic, Inc. today announced the launch of the Nuclear Mitome Test, a genetic test to aid physicians in the diagnosis of mitochondrial disorders.

17 Jun 2011

Life Technologies, Fox Chase partner to provide next-generation sequencing analysis of solid tumors

Fox Chase Cancer Center, one of the nation's leading cancer research and treatment institutions, today announced it has entered into an agreement with Life Technologies Corporation that will underpin a new program to provide next-generation sequencing analysis of solid tumors.

14 Jun 2011

Scientists pioneer way to find more chromosomal aberrations in tumors

Washington University Pediatric Cancer Genome Project scientists pioneer way to find more chromosomal aberrations in tumors; results likely to advance understanding of cancer.

13 Jun 2011

Next generation sequencing NGS News and Research

Medicinal Genomics sequences entire genomes of two therapeutic Cannabis strains

TrovaGene regains ownership of worldwide rights to transrenal technology

Affymetrix announces commercialization of next-generation human transcriptome array

Illumina and University of Oxford collaborate to sequence whole genomes

Mitochondrial genome undergoes random reorganisation during reprogramming

New DNA sequencer will provide deeper insight into gene regulation

Researchers discover new gene linked to intellectual disability

People with long term debilitating physical illness demonstrate mental resilience

Ion Torrent ships three next-generation sequencers

BGI, Covaris partner to provide next generation sequencing technology

Isogenica opens new automation facility

Extensive genomic, transcriptional diversity identified through massively parallel DNA and RNA sequencing

Review of non-smoker patient with lung cancer to be presented at IASLC conference

Genetic mutations in abnormal bone marrow can predict mortality of MDS patients

Start of clinical validation study of Down’s syndrome diagnostic test

Biolauncher, Isogenica and Cresset enter joint venture to develop drug discovery platform

Gene Codes releases Sequencher 5.0

Transgenomic introduces Nuclear Mitome Test for diagnosis of mitochondrial disorders

Life Technologies, Fox Chase partner to provide next-generation sequencing analysis of solid tumors

Scientists pioneer way to find more chromosomal aberrations in tumors

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