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Experts issue new guidelines for use of genetic testing in psychiatric care

An expert committee of psychiatrists and geneticists has issued revised guidelines for the use of genetic testing in psychiatric care.

12 Mar 2019

Adolescent binge drinking may raise risk for anxiety later in life

A growing body of evidence supports the idea that alcohol exposure early in life has lasting effects on the brain and increases the risk of psychological problems in adulthood.

12 Mar 2019

Precision cancer drugs spark powerful immune response and boost effects of immunotherapy

Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients benefit from immunotherapy, a new study reveals.

11 Mar 2019

Research opens up opportunities to unravel the complexity of microbial communities

"Microbial communities run the world," says Jo Handelsman, director of the Wisconsin Institute for Discovery at the University of Wisconsin-Madison.

11 Mar 2019

Researchers identify gene that increases risk of antibiotic reaction

Researchers at Vanderbilt University Medical Center and colleagues have identified a gene that increases the risk for a severe and potentially life-threatening reaction to the commonly prescribed antibiotic vancomycin.

11 Mar 2019

Researchers develop statistical approach to reveal elusive cancer-promoting genes

Australian and US researchers have developed a way to discover elusive cancer-promoting genes, and have already identified one that appears to promote aggressive breast cancers.

11 Mar 2019

Zinc could help develop new non-antibiotic treatment for bacterial diseases

New details about the role of zinc in our immune system could help the development of new non-antibiotic treatment strategies for bacterial diseases, such as urinary tract infections.

9 Mar 2019

Comprehensive analysis of sewage reveals antimicrobial resistance levels worldwide

A comprehensive analysis of sewage collected in 74 cities in 60 countries has yielded the first, comparable global data, which show the levels and types of antimicrobial resistant bacteria that are present in mainly healthy people in these countries.

9 Mar 2019

Researchers unravel how the immune system responds to diffuse cutaneous leishmanisis

In diffuse cutaneous leishmanisis, a rare form of leishmaniasis, parasites grow uncontrolled in skin lesions across the body.

8 Mar 2019

Study reveals how the microbiota controls activity of immune cells

A host protein called Serum Amyloid A (Saa) is a major factor mediating the effects of the microbiota on the function of immune cells called neutrophils, according to a study published March 7 in the open-access journal PLOS Pathogens by John Rawls of Duke University School of Medicine, and colleagues.

8 Mar 2019

UCSF scientists develop new strategy for targeting key Parkinson's molecule

UC San Francisco researchers have for the first time developed a strategy for targeting a key molecule implicated in Parkinson's disease, opening up a potential new treatment strategy for the currently incurable movement disorder.

8 Mar 2019

New gene regions associated with sleep duration identified

A study led by investigators from Massachusetts General Hospital and the University of Exeter Medical School has identified 76 new gene regions associated with sleep duration.

8 Mar 2019

Research shows how SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits

SGLT-2 inhibitors are a relatively new class of diabetes drugs that have shown many benefits for people with type 2 diabetes who have not responded well to previous interventions, including diet changes and metformin.

8 Mar 2019

Novel mouse model confirms how “good” and “bad” bacteria affect human acne

Researchers have long believed that Propionibacterium acnes causes acne. But these bacteria are plentiful on everyone's skin and yet not everyone gets acne, or experiences it to the same degree.

8 Mar 2019

Getting closer to a scary 'post-antibiotic world'

The products of wastewater treatment have been found to contain trace amounts of antibiotic resistant DNA. These products are often reintroduced to the environment and water supply, potentially resulting in the spread of antibiotic resistance.

8 Mar 2019

Scientists shed light on key mechanism linked to development of healthy cells

Scientists have shed light on how healthy cells develop by identifying the role of key molecules involved.

8 Mar 2019

A molecular epigenetic marker can predict survival of children with leukemia

A molecular epigenetic marker is important for distinguishing patients with childhood leukemia at high and low risk of relapse even at the time of diagnosis.

8 Mar 2019

Researchers find potential new target for chronic pain treatment

A research group at Hiroshima University observed a potential new target for chronic pain treatment. Further research using this receptor could lead to new, more effective drugs to use in pain-relieving treatment for chronic pain.

7 Mar 2019

Researchers develop new method to boost efficiency of CRISPR gene editing in DMD

Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases.

7 Mar 2019

Anti-inflammatory drug shown to promote cardiac reprogramming

Once damaged, the human heart does a poor job of repairing itself, so this is a key priority for treating heart failure. One way of restoring cardiac function is to reprogram non-cardiac body cells such as fibroblasts into heart muscle cells (cardiomyocytes) using a collection of cardiac transcription factors.

6 Mar 2019