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Genetic manipulation can double life expectancy and increase health of offspring

By manipulating the genes that make humans age, researchers have discovered that lifespans can be doubled with a better quality of life for offspring.

6 Mar 2019

CSHL scientists create a ranked list of genetic 'usual suspects'

It's no secret that our genes are what makes us... us! But genes are often also the basis for debilitating diseases. One of the major clues to understanding any illness is seeing which genes are acting unusually during disease onset.

6 Mar 2019

Liver tissue model can help investigate the effects of RNA interference

Novel therapies based on a process known as RNA interference hold great promise for treating a variety of diseases by blocking specific genes in a patient's cells. Many of the earliest RNAi treatments have focused on diseases of the liver, because RNA-carrying particles tend to accumulate in that organ.

6 Mar 2019

New insights into influenza A infection and its spread

A new route of influenza A infection viruses has been discovered by the researchers at the Medical Center - University of Freiburg and the University of Zurich. At present the knowledge regarding influenza A infection spread is mainly restricted to the binding of the sialic moieties of the virus to the cell surface of the host.

5 Mar 2019

The presence of cancer-causing contaminant in popular foods

Acrylamide is described as 'extremely hazardous' and 'probably carcinogenic to humans'. Its presence in popular foods, including fried, baked, roasted and toasted potato and cereal products, as well as coffee, has become one of the most difficult issues facing the food industry, its supply chain, retailers and regulators.

5 Mar 2019

Study sheds new light on early development of embryos

By applying gene analysis to individual cells from early mouse embryos, researchers at Karolinska Institutet in Sweden have discovered previously unknown cellular stages of fetal development from fertilized egg to living being. The study is published in the scientific journal Cell Reports.

5 Mar 2019

Study reveals hidden risks of diarrheal disease in children

A rapidly evolving new subspecies of the cryptosporidium parasite – a leading cause of diarrheal disease in children worldwide – has been revealed by scientists at the University of East Anglia.

5 Mar 2019

Genetic breakthrough could pave way for a new drug to prevent, heal painful mouth ulcers

A large breakthrough has been made in the genetic understanding of mouth ulcers which could provide potential for a new drug to prevent or heal the painful lesions.

5 Mar 2019

Researchers identify common genetic signature among three rare skin diseases

A group of researchers lead by a lecturer from the Universidad Carlos III de Madrid, Marcela del Río, from the CIEMAT, the Rare Diseases Networking Biomedical Research Centre and Fundación Jiménez Díaz has identified a common genetic signature among three rare skin diseases or genodermatoses: recessive dystrophic epidermolysis bullosa, Kindler syndrome and xeroderma pigmentosum.

5 Mar 2019

Genomics could guide treatment for pancreatic cancer patients

Pancreatic cancer is a grim diagnosis, with a five-year survival rate of less than 9 percent. To improve those odds, researchers at UPMC and the University of Pittsburgh School of Medicine sought genetic signatures in the largest study of its kind that could be used to better match drugs to patients and for early detection.

5 Mar 2019

Researchers identify first genetic defect linked to biliary atresia

A nationwide consortium of researchers has identified the first genetic defect linked to biliary atresia, a mysterious liver disease that is the leading cause for liver transplantation in children.

5 Mar 2019

Radiation after surgery in children with ependymoma nearly triples survival rate

Radiation immediately following surgery in children with ependymoma, the third most common pediatric brain tumor, can nearly triple survival.

5 Mar 2019

Study finds how miR-132 acts as ‘handbrake’ on our immune system

Researchers have discovered how a tiny molecule known as miR-132 acts as a "handbrake" on our immune system - helping us fight infection.

5 Mar 2019

New combinational drug therapy may effectively combat pancreatic cancer

Even among cancers, pancreatic cancer is an especially sinister form of disease. The one-year survival rate is extremely low, and treatment progress has lagged behind that of many other malignancies.

5 Mar 2019

New clinical genomic testing helps identify mutations that drive childhood melanoma

Comprehensive clinical genomic testing of an adolescent patient, including whole genome sequencing, helped researchers identify mutations in a single gene that drive the most common childhood melanoma.

5 Mar 2019

Microbes causing cystic fibrosis change rapidly within 2-3 years after first infection

A new study, recently published in Nature Communications, has looked at infections in Danish youth with CF over a period of 10 years. This is the largest longitudinal study to date of the evolution - both involving traits and genes - of the disease-causing microbes that persistently infect young CF-patients.

5 Mar 2019

New study discovers entirely new infection route for influenza A viruses

Researchers from the Medical Center - University of Freiburg and the University of Zurich have discovered an entirely new infection route for influenza A viruses.

5 Mar 2019

World-first fact-checking program tackles problem of incorrect biomedical research results

Cancer researcher Professor Jennifer Byrne from the University of Sydney is hoping to change this with the creation of a world-first fact-checking program that is tackling the problem of incorrectly published biomedical research results, whether intentional or otherwise.

5 Mar 2019

Scientists discover new infection route for influenza A viruses

The immunologically relevant MHC class II molecules are ubiquitously found in many animal species, which is why the discovery will play an important role in assessing the risk of spill-over infections to other species than bats.

4 Mar 2019

Research opens door to promising new treatment strategy for deadly brain tumor in children

A study published in Nature Communications found that an inhibitor of an enzyme called ACVR1 slows tumor growth and increases survival in an animal model of diffuse intrinsic pontine glioma - the most deadly brain tumor in children.

4 Mar 2019