Neurons News and Research

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Math1 gene plays a pivotal role in the formation of many of the neurons important in hearing and balance

Close your eyes and imagine you are in a darkened Carnegie Hall. Although it's pitch black, you know you are getting closer to the stage as the music gets louder. If you have been there before, you have a sense of the location of the seats and aisles.

5 Oct 2005

Immature stem cells that proliferate to form brain tissues in mice can function for at least a year

New studies in mice have shown that immature stem cells that proliferate to form brain tissues can function for at least a year -- most of the life span of a mouse -- and give rise to multiple types of neural cells, not just neurons.

5 Oct 2005

Discovery has implications for research on restoring mobility to people who have lost motor functions due to spinal cord injury

Yale School of Medicine researchers report in Science this week genetic evidence for the hypothesis that myelination, or formation of a protective sheath around a nerve fiber, consolidates neural circuitry by suppressing plasticity in the mature brain.

3 Oct 2005

Potential beneficial effect of copper orotate

As one of the services for patients with Alzheimer's disease, the Department of Psychiatry at the Saarland University Medical Center offers participation in a clinical phase II trial. This clinical trial aims to elucidate a potential beneficial effect of copper orotate (an organic copper salt), which is given together with a standard cholinesterase inhibitor.

3 Oct 2005

Ubiquitin ligase Rnf6 may be involved in oncogenesis

In a recent study, Dr. Ingolf Bach and colleagues from the University of Massachusetts Medical School, Worcester and the University of Hamburg describe a novel role for the ubiquitin/proteosome protein degradation pathway in the regulation of local actin dynamics in neurons.

3 Oct 2005

Extreme gene pin-pointed

One teenager likes to snowboard off a cliff. Another prefers to read a book and wouldn't think of trading places. Why these differences exist is a mystery, but for the first time researchers have identified a possible genetic explanation behind risk-seeking behavior.

26 Sep 2005

Surprising immune system cells discovery

Immune system cells are connected to each other by an extensive network of tiny tunnels that, like a building's hidden pneumatic tube system, are used to shoot signals to distant cells.

26 Sep 2005

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

Neurologix has announced positive interim results of its landmark gene therapy clinical trial for patients with Parkinson's disease. Neurologix's 12-patient, dose-escalating Phase I trial is the world's first study to use a viral vector (the non-pathogenic adeno-associated virus, or AAV) for the treatment of an adult neurological disease.

26 Sep 2005

New information about how the brain directs the body to make movements

A University of California - San Francisco (UCSF) study has revealed new information about how the brain directs the body to make movements. The key factor is "noise" in the brain's signaling, and it helps explain why all movement is not carried out with the same level of precision.

26 Sep 2005

Adult human neural stem cells used to successfully regenerate spinal cord tissue

Researchers at the UC Irvine Reeve-Irvine Research Center have used adult human neural stem cells to successfully regenerate damaged spinal cord tissue and improve mobility in mice.

26 Sep 2005

Key neural system at risk from prenatal exposure to alcohol

In a study of adult monkeys who were exposed to moderate amounts of alcohol in utero, scientists have found that prenatal exposure to alcohol - even in small doses - has pronounced effects on the development and function later in life of the brain's dopamine system, a critical component of the central nervous system that regulates many regions of the brain.

21 Sep 2005

Phantom pain following spinal cord injury is the result of hypersensitive neurons in the thalamic region of brain

Yale researchers report the first evidence that phantom pain following spinal cord injury is the result of hypersensitive neurons in the thalamic region of the brain that can be suppressed with specially designed molecular agents.

20 Sep 2005

First large-scale whole genome map of genetic variability associated with Parkinson's disease

Mayo Clinic researchers in collaboration with scientists at Perlegen Sciences, Inc. and funded by the Michael J. Fox Foundation for Parkinson's Research have produced the first large-scale whole genome map of genetic variability associated with Parkinson's disease.

19 Sep 2005

Finding may significantly broaden understanding of how the brain selects and retains information

By examining how sounds are registered during the process of learning, UC Irvine neurobiologists have discovered a neural coding mechanism that the brain relies upon to register the intensity of memories based on the importance of the experience.

12 Sep 2005

Microtubules critical to development of mental disorders

Neuroscientists at the University at Buffalo have shown in two recently published papers that destabilization of structures called microtubules, intracellular highways that transport receptors to their working sites in the brain, likely underlie many mental disorders and could be promising targets for intervention.

12 Sep 2005

Translation elongation factor eEF1A2 is is a potential oncogene that is overexpressed in two-thirds of breast tumors

The tissue-specific elongation factor eEF1A2 might be an oncoprotein involved in breast cancer.

12 Sep 2005

Clioquinol appears to block the genetic action of Huntington's disease

Clioquinol, an antibiotic that was banned for internal use in the United States in 1971 but is still used in topical applications, appears to block the genetic action of Huntington's disease in mice and in cell culture, according to a study reported by San Francisco VA Medical Center (SFVAMC) researchers.

12 Sep 2005

Sugar-coated markers of brain cell development may help success of stem cell transplants

Four sugar-coated faces made by stem cells as they differentiate into brain cells during development have been identified by scientists.

10 Sep 2005

Researchers discover discrete region of the monkey brain that processes pitch

Johns Hopkins researchers have discovered a discrete region of the monkey brain that processes pitch, the relative high and low points of sound, by recognizing a single musical note played by different instruments.

7 Sep 2005

Animal model of Parkinson's disease reveals striking sensitivity to common environmental toxins

In findings that support a relationship between agricultural chemicals and Parkinson's disease, two groups of researchers have found new evidence that loss of DJ-1, a gene known to be linked to inherited Parkinson's disease, leads to striking sensitivity to the herbicide paraquat and the insecticide rotenone.

7 Sep 2005

Neurons News and Research

Math1 gene plays a pivotal role in the formation of many of the neurons important in hearing and balance

Immature stem cells that proliferate to form brain tissues in mice can function for at least a year

Discovery has implications for research on restoring mobility to people who have lost motor functions due to spinal cord injury

Potential beneficial effect of copper orotate

Ubiquitin ligase Rnf6 may be involved in oncogenesis

Extreme gene pin-pointed

Surprising immune system cells discovery

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

New information about how the brain directs the body to make movements

Adult human neural stem cells used to successfully regenerate spinal cord tissue

Key neural system at risk from prenatal exposure to alcohol

Phantom pain following spinal cord injury is the result of hypersensitive neurons in the thalamic region of brain

First large-scale whole genome map of genetic variability associated with Parkinson's disease

Finding may significantly broaden understanding of how the brain selects and retains information

Microtubules critical to development of mental disorders

Translation elongation factor eEF1A2 is is a potential oncogene that is overexpressed in two-thirds of breast tumors

Clioquinol appears to block the genetic action of Huntington's disease

Sugar-coated markers of brain cell development may help success of stem cell transplants

Researchers discover discrete region of the monkey brain that processes pitch

Animal model of Parkinson's disease reveals striking sensitivity to common environmental toxins

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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