B Cell News and Research

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New compound proves to be potent against more than 300 drug-resistant bacteria

Urinary tract infections are common, yet are increasingly tough to treat because the bacteria that cause them are becoming resistant to many antibiotics.

10 Aug 2022

How ultraprocessed foods affect gut microbiome and health

Researchers describe the association between the consumption of ultraprocessed foods and chronic medical conditions.

10 Aug 2022

Research may lead the way to a simpler treatment for cancer

Sometimes too much of a good thing is not good at all. Inhibiting the function of the PD-1 protein, which blocks immune function, has shown high therapeutic efficacy in cancer immunotherapy.

10 Aug 2022

Scientists discover new target for treatment of premature aging disorders

A stretch of DNA that hops around the human genome plays a role in premature aging disorders, scientists at the Salk Institute and King Abdullah University of Science and Technology in Saudi Arabia have discovered.

10 Aug 2022

UTSW scientists discover mechanism of RNA capping by SARS-CoV-2 virus

A team led by UT Southwestern researchers has identified how SARS-CoV-2, the virus that causes COVID-19, builds a structure called the RNA cap that's critical for successful viral replication.

10 Aug 2022

Study finds genetic alterations in healthy cells that match with the tumor cells

A new study offers the possibility of unmasking genetic mutations in an organ well before commonly-used screening techniques detect signs of cancer.

10 Aug 2022

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

In a study recently published in Cancer Research, a journal of the American Association for Cancer Research, a team of researchers led by C. Patrick Reynolds, M.D., Ph.D., director for the Texas Tech University Health Sciences Center School of Medicine Cancer Center, sought to expand upon his lab's previous research that showed ALT tumors identified by a biomarker known as C-circles share a common biology that confers vulnerabilities to be exploited for cancer therapy.

10 Aug 2022

Scientists explore ecological firewalls for the containment of synthetic microbes

In a new study, researchers described ecological firewalls (EFWs) to contain synthetic microbes.

10 Aug 2022

Review of natural products with promising anti-SARS-CoV-2 potential

In a new study, researchers reviewed existing literature on naturally active products with therapeutic efficacy against SARS-CoV-2.

10 Aug 2022

The features of the newly emerging SARS-CoV-2 Omicron BA.2.75 subvariant

Researchers evaluated all the features, especially the antigenic properties and transmission potential of SARS-CoV-2 Omicron sub-variant BA.2.75.

10 Aug 2022

A direct lineage-typing RT-PCR assay reveals insights into the transition from Omicron BA.1 to BA.2 dominance in Sweden

Researchers monitored the remarkably rapid Omicron BA.1 to BA.2 sublineage dominance transition in the Swedish population in early 2022 on a day-to-day basis using a customized lineage-typing RT-PCR assay.

10 Aug 2022

Researchers explore SARS-CoV-2 entry route and downstream cellular and viral processes

In a new study, researchers assessed the impact of the SARS-CoV-2 entry route on downstream cellular and viral processes.

10 Aug 2022

Coronavirus biology: viral RNA synthesis, origin, and vaccines

Researchers analyzed the characteristics of coronaviruses and novel CoV vaccine candidates.

10 Aug 2022

Study shows how the same protein that is key for brain development can also be the cause for the spread of cancer

Researchers at Queen's University Belfast have revealed how the pathway of an identified protein could lead to early diagnosis and targeted treatment for several cancers and brain disorders.

10 Aug 2022

British Heart Foundation funded Surrey project will address cardiac safety in novel anti-malarial agents

Understanding how drugs used to treat malaria impact the human heart is essential to finally toppling one of the world's most common but serious infections, according to researchers at the University of Surrey.

10 Aug 2022

IRB scientists identify critical spots on the genome where gene editing could cause an unwanted response

CRISPR/Cas9 is a commonly used, very precise, gene editing technique whose development, by Jennifer A. Doudna and Emmanuelle Charpentier, was recognised with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors", CRISPR allows the introduction of the desired DNA sequence into (virtually) any spot of the genome, thus modifying or inactivating a gene. This technique is widely used in biomedical research and some CRISPR-based therapies are in clinical trials for the treatment of human blood disorders, some types of cancer and HIV, among other conditions.

10 Aug 2022

Novel class of drug regresses active brain metastases in breast cancer patients

An Austrian study led by MedUni Vienna showed that active brain metastases in breast cancer patients are partially or even completely regressed by a novel class of drug. This is a chemical conjugate of an antibody and a chemotherapy drug that, according to current findings, opens up a completely new avenue in oncological research and targeted therapy.

10 Aug 2022

Researchers identify novel molecular pathway that suppresses the spread of glioblastoma

UT Southwestern researchers have identified a molecular pathway responsible for the spread of glioblastoma to surrounding tissue in the brain, as well as an existing drug that curbed tumor growth in animal models.

10 Aug 2022

Study evaluates the tumor-modulatory effects of opsins on melanoma cancer

Melanopsin (OPN4) is a light-sensing protein found in skin and retina cells. A new study conducted at the University of São Paulo (USP) in Brazil suggests that OPN4 can also participate in the development and progression of melanoma, the most aggressive type of skin cancer.

10 Aug 2022

A broad sarbecovirus-neutralizing antibody cocktail

Researchers present a rational approach for identifying SARS-CoV-2 receptor-binding domain-targeted broad neutralizing antibody cocktails.

9 Aug 2022

B Cell News and Research

New compound proves to be potent against more than 300 drug-resistant bacteria

How ultraprocessed foods affect gut microbiome and health

Research may lead the way to a simpler treatment for cancer

Scientists discover new target for treatment of premature aging disorders

UTSW scientists discover mechanism of RNA capping by SARS-CoV-2 virus

Study finds genetic alterations in healthy cells that match with the tumor cells

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

Scientists explore ecological firewalls for the containment of synthetic microbes

Review of natural products with promising anti-SARS-CoV-2 potential

The features of the newly emerging SARS-CoV-2 Omicron BA.2.75 subvariant

A direct lineage-typing RT-PCR assay reveals insights into the transition from Omicron BA.1 to BA.2 dominance in Sweden

Researchers explore SARS-CoV-2 entry route and downstream cellular and viral processes

Coronavirus biology: viral RNA synthesis, origin, and vaccines

Study shows how the same protein that is key for brain development can also be the cause for the spread of cancer

British Heart Foundation funded Surrey project will address cardiac safety in novel anti-malarial agents

IRB scientists identify critical spots on the genome where gene editing could cause an unwanted response

Novel class of drug regresses active brain metastases in breast cancer patients

Researchers identify novel molecular pathway that suppresses the spread of glioblastoma

Study evaluates the tumor-modulatory effects of opsins on melanoma cancer

A broad sarbecovirus-neutralizing antibody cocktail

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