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Perimenopausal women at greater risk for developing insomnia

Millions of women may likely be sleep-deprived. It's already a known fact that women are more predisposed to insomnia. Now a new study presented at the 2015 Annual Meeting of The North American Menopause Society earlier this month suggests that perimenopausal women have an even greater risk for developing insomnia. Considering that perimenopause will affect roughly 500 million women within the next decade, that's a lot of tired women.

15 Oct 2015

Gene therapy preserves vision in canine model of late-stage retinitis pigmentosa

Gene therapy preserved vision in a study involving dogs with naturally occurring, late-stage retinitis pigmentosa, according to research funded by the National Eye Institute (NEI), part of the National Institutes of Health. The findings contribute to the groundwork needed to move gene therapy forward into clinical trials for people with the blinding eye disorder, for which there is currently no cure.

15 Oct 2015

Poorly-designed animal study threatens validity of preclinical research

Badly designed studies may lead to the efficacy of drugs being overestimated and money being wasted on trials that prove fruitless, according to new a study from McGill University in Canada.

15 Oct 2015

Specific gene signature could help predict survival outcomes among children with intermediate-risk RMS

Among children with intermediate-risk rhabdomyosarcoma (RMS) that is negative for a fusion gene, those who had a high score of a specific gene signature called MG5 had poorer survival outcomes compared with those who had a low score of MG5.

15 Oct 2015

Computers can be as good as doctors and nurses in predicting patient discharges

A computer can do as good a job of predicting how many patients will be discharged from a hospital unit on a given day as doctors and nurses can, according to new research from the University of Maryland's Robert H. Smith School of Business and Johns Hopkins University. In some cases, the computer does even better.

15 Oct 2015

Researchers reveal effects of Affordable Care Act on low-income Virginians with HIV

In an important examination of the effect of the Affordable Care Act, researchers have determined that low-income Virginians with HIV had better outcomes when enrolled in Affordable Care Act healthcare plans. The study is believed to be the first to compare Affordable Care Act outcomes with the previous standard of care for this vulnerable patient population.

15 Oct 2015

CWRU investigator receives $2.82 million NIH grant to make stealth bombs for brain cancer treatment

A Case Western Reserve University researcher has received a 5-year, $2.82 million National Institutes of Health grant to make, in essence, stealth bombs that slip past the brain's defenses to attack an incurable form of cancer.

15 Oct 2015

Only few doctors refer children with developmental delays to genetics specialists, say researchers

A nine-month-old boy isn't rolling over, reaching for objects or babbling as he should be. One step his doctor won't likely take right away: have him evaluated by a genetics specialist.

15 Oct 2015

New blood test could help pair cancer patients with suitable therapy for their disease

CANCER RESEARCH UK-funded scientists have developed a blood test that could help pair cancer patients with the most suitable therapy for their disease and then track the tumour's progress to see if the treatment is working, according to research published today (Thursday) in Clinical Cancer Research.

15 Oct 2015

Having a high stress job may increase risk of stroke

Having a high stress job may be linked to a higher risk of stroke, according to an analysis of several studies. The meta-analysis is published in the October 14, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

15 Oct 2015

Bio-molecules present in human breast milk can help resolve inflammation, combat infection

Human breast milk, which provides essential nutrients and antibodies to newborns, has long been known to play an important role in infant development and the immune system. In a new study published in Mucosal Immunology, researchers from Brigham and Women's Hospital report that human breast milk serves as a reservoir for bio-molecules that help to resolve inflammation and combat infection.

15 Oct 2015

New $6.7 million project aims to help kidney dialysis patients live longer

Helping kidney dialysis patients have healthier treatment sessions and longer lives is the goal of a new $6.7 million project at the University of Michigan.

15 Oct 2015

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

An international research team led by scientists at the University of New Mexico Cancer Center discovered and developed a novel ligand peptide-mimic that inhibits abnormal overgrowth of blood vessels in retinal diseases and tumors. The discovery could lead to new drugs that keep cancers from growing. The team published a paper in the journal Science Translational Medicine.

15 Oct 2015

TxCell reviews its manufacturing strategy to focus on R&D and strategic partnerships - its core, high added value businesses

TxCell SA, a biotechnology company developing innovative, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that it is operating a strategic review that should result in the outsourcing of all existing and future clinical and commercial manufacturing operations to contract manufacturing organizations (CMOs).

15 Oct 2015

SRS microscope technology gives surgeons real-time microscopic vision of brain tumors

Brain tumor tissue can be hard to distinguish from normal brain during surgery. Neurosurgeons use their best judgment in the operating room but often must guess exactly where the edges of the tumor are while removing it.

15 Oct 2015

Different Crohn's disease treatments affect children's gut microbes in distinct ways

Different treatments for Crohn's disease in children affects their gut mi-crobes in distinct ways, which has implications for future development of microbial-targeted therapies for these patients, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

15 Oct 2015

LEADERS FREE clinical trial demonstrates superior safety, efficacy for BioFreedom compared with bare-metal stent

Biosensors International Group, Ltd., a developer, manufacturer and marketer of innovative medical devices, announced today that the LEADERS FREE clinical trial demonstrated superior safety and efficacy for BioFreedom compared with a bare-metal stent (BMS).

15 Oct 2015

Merck unveils new global brand as a science and technology company

Merck, a leading science and technology company, today announced the relaunch of its brand identity. The fundamental revision of the visual appearance as well as the introduction of a new logo reflect the transformation into a global science and technology company. At the same time, the brand architecture at business level has been simplified. Outside the United States and Canada, the company will operate uniformly as Merck.

15 Oct 2015

Researchers link organ transplant drug to rise in rare lymphoma

A study led by Johns Hopkins researchers has linked the immunosuppressive drug mycophenolate mofetil (MMF) to an increased risk of central nervous system (CNS) lymphoma in solid organ transplant patients. But the same study also found that another class of immunosuppressive drugs, called calcineurin inhibitors (CNIs), given alone or in combination with MMF, appears to protect transplant patients against this rare form of lymphoma.

15 Oct 2015

First-in-human compassionate use cases with Edwards' FORMA transcatheter tricuspid repair system presented at TCT

Edwards Lifesciences Corporation, the global leader in the science of heart valves and hemodynamic monitoring, today announced that details on the 13 first-in-human compassionate use cases with its FORMA transcatheter tricuspid repair system were presented at the 27th Transcatheter Cardiovascular Therapeutics (TCT), the annual scientific symposium of the Cardiovascular Research Foundation.

15 Oct 2015

Research News and Research

Perimenopausal women at greater risk for developing insomnia

Gene therapy preserves vision in canine model of late-stage retinitis pigmentosa

Poorly-designed animal study threatens validity of preclinical research

Specific gene signature could help predict survival outcomes among children with intermediate-risk RMS

Computers can be as good as doctors and nurses in predicting patient discharges

Researchers reveal effects of Affordable Care Act on low-income Virginians with HIV

CWRU investigator receives $2.82 million NIH grant to make stealth bombs for brain cancer treatment

Only few doctors refer children with developmental delays to genetics specialists, say researchers

New blood test could help pair cancer patients with suitable therapy for their disease

Having a high stress job may increase risk of stroke

Bio-molecules present in human breast milk can help resolve inflammation, combat infection

New $6.7 million project aims to help kidney dialysis patients live longer

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

TxCell reviews its manufacturing strategy to focus on R&D and strategic partnerships - its core, high added value businesses

SRS microscope technology gives surgeons real-time microscopic vision of brain tumors

Different Crohn's disease treatments affect children's gut microbes in distinct ways

LEADERS FREE clinical trial demonstrates superior safety, efficacy for BioFreedom compared with bare-metal stent

Merck unveils new global brand as a science and technology company

Researchers link organ transplant drug to rise in rare lymphoma

First-in-human compassionate use cases with Edwards' FORMA transcatheter tricuspid repair system presented at TCT

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