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Scientists uncover a key cellular mechanism that alters brain cell function in Huntington's disease

Scientists at the Brain Research Centre and Centre for Molecular Medicine and Therapeutics have uncovered a key cellular mechanism that alters brain cell function in Huntington's disease, and identified a possible treatment for the disease.

28 Jan 2010

Researchers develop PEG-POD tool for gene therapy

Researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts have developed a new tool for gene therapy that significantly increases gene delivery to cells in the retina compared to other carriers and DNA alone, according to a study published in the January issue of The Journal of Gene Medicine.

28 Jan 2010

Discovery could help improve diagnosis and treatment for anxiety disorders

Draw a map of the brain when fear and anxiety are involved, and the amygdala-the brain's almond-shaped center for panic and fight-or-flight responses-looms large.

27 Jan 2010

Abbott declares quarterly dividend of 40 cents per share

Abbott today announced financial results for the fourth quarter ended Dec. 31, 2009.

27 Jan 2010

National Science Foundation awards grant to study biological mechanism of living cells

Learning how living cells can detect and respond to electric fields is the aim of a $570,000, three-year grant from the National Science Foundation to Min Zhao, professor of dermatology and ophthalmology at the UC Davis Health System and Center for Neuroscience.

27 Jan 2010

UF researchers work out to find new treatments for Pompe disease

As scientists work to find new treatments for Pompe disease - the devastating genetic "villain" that drives the efforts of the main characters in the new film "Extraordinary Measures" - University of Florida researchers are hopeful that gene therapy will help patients in the late stages of the disease breathe on their own.

27 Jan 2010

UCSB research: Rapamycin drug, a potential treatment for ADPKD

Research performed at UC Santa Barbara points to the drug rapamycin as a potential treatment for kidney disease. The study builds on past research and shows that studies performed on mice are more likely to translate to humans than previously thought.

27 Jan 2010

AAN guideline finds diazepam drug is effective for treating children with cerebral palsy

A new guideline from the American Academy of Neurology and the Child Neurology Society finds botulinum toxin type A to be an effective treatment for spasticity, muscle tightness that interferes with movement, in children and adolescents with cerebral palsy, but poses some risk.

27 Jan 2010

Testing DBS for treating severe long-term depression

Bewernick and colleagues administered DBS treatment in ten patients with severe long-term depression who had not responded to multiple other antidepressant treatments, including psychotherapy, drug treatments and electroconvulsive treatment. After one year of DBS, all patients showed some improvement, and half of them experienced significant improvement in their symptoms of depression, astonishing considering they had not responded to any prior antidepressant treatment. In addition, the patients showed reduced ratings of anxiety and had only minor side effects. Importantly, none of their overall brain functioning was impaired by the DBS treatment.

27 Jan 2010

Promising results in mice could prevent fatal iron buildup in humans

A new study shows that a protein found in blood alleviates anemia, a condition in which the body's tissues don't get enough oxygen from the blood. In this animal study, injections of the protein, known as transferrin, also protected against potentially fatal iron overload in mice with thalassemia, a type of inherited anemia that affects millions of people worldwide.

27 Jan 2010

NCMHD awards Weill Cornell Medical College $8M for establishing CEDREC in New York City

Weill Cornell Medical College has established a new research center to improve medical care in ethnically diverse and medically underserved communities in New York City.

23 Jan 2010

Findings offer potential significance to the recovery of walking after spinal cord injury

Researchers at the medical university Karolinska Institutet have created a genetically modified mouse in which certain neurons can be activated by blue light. Shining blue light on brainstems or spinal cords isolated from these mice produces walking-like motor activity. The findings, which are published in the scientific journal Nature Neuroscience, are of potential significance to the recovery of walking after spinal cord injury.

22 Jan 2010

Virtual-reality baseballs give researchers insight into long-standing mystery

While baseball fans still rank "The Catch" by Willie Mays in the 1954 World Series as one of the greatest baseball moments of all times, scientists see the feat as more of a puzzle: How does an outfielder get to the right place at the right time to catch a fly ball?

22 Jan 2010

Combat injuries are not the leading cause of medical evacuation from war zones

The most common reasons for medical evacuation of military personnel from war zones in Iraq and Afghanistan in recent years have been fractures, tendonitis and other musculoskeletal and connective tissue disorders, not combat injuries, according to results of a Johns Hopkins study published January 22 in The Lancet.

22 Jan 2010

Researchers identify new therapeutic approach for stroke treatment

For the first time, research led by Youming Lu, PhD, MD, Professor of Neurology and Neuroscience at LSU Health Sciences Center New Orleans School of Medicine, has identified a novel mechanism that may trigger brain damage during stroke and identified a therapeutic approach to block it.

22 Jan 2010

Findings may provide new insights into diabetes; suggest novel targets for drug intervention

The neuropeptide corticotropin-releasing factor (CRF) makes cameo appearances throughout the body, but its leading role is as the opening act in the stress response, jump-starting the process along the hypothalamus-pituitary-adrenal (HPA) axis. Researchers at the Salk Institute for Biological Studies have found that CRF also plays a part in the pancreas, where it increases insulin secretion and promotes the division of the insulin-producing beta cells.

22 Jan 2010

Findings may aid in developing therapeutic drugs for stroke and other neurodegenerative diseases

Biomedical scientists from the University of Central Florida and Louisiana State University have identified a way to block a "cell death signal" that they believe triggers brain damage during strokes.

22 Jan 2010

Thomas S. Kilduff named a Fellow of the AAAS

SRI International, an independent nonprofit research and development institute, announced today that Thomas S. Kilduff, Ph.D., director of SRI International's Center for Neuroscience, has been named a Fellow of the American Association for the Advancement of Science (AAAS).

22 Jan 2010

Consistent pattern of cognitive deficits during childhood leads to adult schizophrenia

Years before adults develop schizophrenia, there is a pattern of cognitive difficulties they experience as children, including problems with verbal reasoning, working memory, attention and processing speed.

22 Jan 2010

Neuralstem announces treatment of first ALS patient with spinal cord stem cells

Neuralstem, Inc. announced that the first ALS patient was treated with its spinal cord stem cells yesterday at the Emory ALS Center at Emory University, in Atlanta, GA. A total of up to 18 patients is planned to be treated in this first U.S. clinical trial to evaluate human neural stem cells for the treatment of ALS (Amyotrophic Lateral Sclerosis, or Lou Gehrig's disease). ALS affects roughly 30,000 people in the U.S., with about 5,600 new diagnoses per year, according to the ALS Association.

21 Jan 2010

Neuroscience News and Research

Scientists uncover a key cellular mechanism that alters brain cell function in Huntington's disease

Researchers develop PEG-POD tool for gene therapy

Discovery could help improve diagnosis and treatment for anxiety disorders

Abbott declares quarterly dividend of 40 cents per share

National Science Foundation awards grant to study biological mechanism of living cells

UF researchers work out to find new treatments for Pompe disease

UCSB research: Rapamycin drug, a potential treatment for ADPKD

AAN guideline finds diazepam drug is effective for treating children with cerebral palsy

Testing DBS for treating severe long-term depression

Promising results in mice could prevent fatal iron buildup in humans

NCMHD awards Weill Cornell Medical College $8M for establishing CEDREC in New York City

Findings offer potential significance to the recovery of walking after spinal cord injury

Virtual-reality baseballs give researchers insight into long-standing mystery

Combat injuries are not the leading cause of medical evacuation from war zones

Researchers identify new therapeutic approach for stroke treatment

Findings may provide new insights into diabetes; suggest novel targets for drug intervention

Findings may aid in developing therapeutic drugs for stroke and other neurodegenerative diseases

Thomas S. Kilduff named a Fellow of the AAAS

Consistent pattern of cognitive deficits during childhood leads to adult schizophrenia

Neuralstem announces treatment of first ALS patient with spinal cord stem cells

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