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Can SARS-CoV-2 host factor protein interactions help identify antiviral drug targets?

In a new study proteomic peptide-phage display is utilized to profile the novel SLiM-based interactions that mediate host factor interactions in 229 RNA viruses, with a special focus on SARS-CoV-2, to reveal mechanistic insights and identify drug targets.

22 Apr 2021

After accident, patient crashes into $700,000 bill for spine surgery

Mark Gottlieb's life changed in an instant when another driver crashed into his car, damaging four vertebrae in his upper spine and smashing six teeth.

22 Apr 2021

Impact of proposed law would increase regulatory oversight of certain diagnostic tests

Legislation currently under consideration in the U.S. Congress would increase regulatory oversight of certain diagnostic tests, and a new study by researchers at Massachusetts General Hospital (MGH) and colleagues from several other institutions demonstrates that its potential impact will depend on key details in the bill's final language.

22 Apr 2021

Study casts doubt on promotion of 'Heat not Burn' products as less harmful alternative to cigarettes

The impact on lung cells of Heat not Burn products--a hybrid between traditional cigarettes and electronic vaping devices--may be no less harmful than that of conventional cigarettes, suggest the findings of a small comparative study, published online in the journal Thorax.

22 Apr 2021

Stem cell therapy can repair brain damage and improve memory function in mice

A one-time injection of an experimental stem cell therapy can repair brain damage and improve memory function in mice with conditions that replicate human strokes and dementia, a new UCLA study finds.

21 Apr 2021

Henry Ford receives $250,000 grant to reduce prostate cancer disparities among Black men

Henry Ford Cancer Institute has received a $250,000 grant from Pfizer Global Medical Grants and the American Cancer Society to reduce prostate cancer disparities among Black men.

21 Apr 2021

Novel approach to gene editing bypasses disease-causing mutations in a gene

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

21 Apr 2021

Listening to music can help older adults sleep better, finds study

A new study published in the Journal of the American Geriatrics Society has found that listening to music can help older adults sleep better.

21 Apr 2021

Interfering RNA nanoparticles could be a potential COVID-19 therapy

Study shows lipid nanoparticle-based siRNA is potent in suppressing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative agent of coronavirus disease 2019 (COVID-19) – in cells as well as in mice models.

21 Apr 2021

Listening to music before going to bed can improve sleep quality among older adults

Listening to music before going to be can improve sleep quality among older adults, according to an analysis of all relevant published clinical trials.

21 Apr 2021

Characterization of lab-produced neutralizing antibodies targeting SARS-CoV-2

A new study led by Hans-Martin Jäck of the Friedrich-Alexander University Erlangen-Nuremberg in Germany engineered clusters of neutralizing monoclonal antibodies using a transgenic mouse model. A unique characteristic for the antibodies was the different ways it bound to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the overall reduction in the viral spread for human ACE2.

21 Apr 2021

Researchers identify differences in immune response in asymptomatic versus severe COVID-19 cases

The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.

21 Apr 2021

Widely available HIV testing and treatment services increase life expectancy

Life expectancy among adults living with HIV receiving antiretroviral therapy (ART) in Latin America and the Caribbean has increased significantly since HIV testing and treatment services became more widely available, according to research published today in The Lancet HIV journal.

21 Apr 2021

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

A chemist from Purdue University has found a way to synthesize a compound to fight a previously "undruggable" cancer protein with benefits across a myriad of cancer types.

20 Apr 2021

Study investigates severe lung injuries among e-cigarette users in rural Appalachia

Just as e-cigarette ingredients can vary from one region to another, the health effects of vaping can have regional characteristics as well. A new study out of West Virginia University suggests that rural e-cigarette users are older--and often get sicker--than their urban counterparts.

20 Apr 2021

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

A first participant was dosed at I-Motion, the pediatric clinical trial platform for neuromuscular diseases located at Trousseau hospital in Paris, as part of the gene therapy trial in Duchenne muscular dystrophy (DMD) conducted by Genethon.

20 Apr 2021

Study identifies higher mortality risk for women with back pain

New research from Boston Medical Center identifies elevated mortality risk for women with back pain when compared to women without back pain. Back pain was not associated with mortality among men indicating long-term consequences of back pain may differ by sex.

20 Apr 2021

Therapy News and Research

Can SARS-CoV-2 host factor protein interactions help identify antiviral drug targets?

After accident, patient crashes into $700,000 bill for spine surgery

Impact of proposed law would increase regulatory oversight of certain diagnostic tests

Study casts doubt on promotion of 'Heat not Burn' products as less harmful alternative to cigarettes

Stem cell therapy can repair brain damage and improve memory function in mice

Henry Ford receives $250,000 grant to reduce prostate cancer disparities among Black men

Novel approach to gene editing bypasses disease-causing mutations in a gene

Listening to music can help older adults sleep better, finds study

Interfering RNA nanoparticles could be a potential COVID-19 therapy

Listening to music before going to bed can improve sleep quality among older adults

Characterization of lab-produced neutralizing antibodies targeting SARS-CoV-2

Researchers identify differences in immune response in asymptomatic versus severe COVID-19 cases

Widely available HIV testing and treatment services increase life expectancy

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

Study investigates severe lung injuries among e-cigarette users in rural Appalachia

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

Study identifies higher mortality risk for women with back pain

Probiotic L. acidophilus can effectively treat intestinal inflammation, research shows

Targeted therapy may be of great benefit in early stage breast cancer

MIND Institute study of anxiety in children with ASD has now expanded to offer online treatment

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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