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Modest reduction in beta-amyloidogenic processing of APP may be a viable strategy to prevent Alzheimer's disease

A new study conducted by researchers at the University of Eastern Finland discovered that the APP A673T genetic variant, which protects against Alzheimer’s disease, alters levels of several proteins and peptides linked to amyloid-beta metabolism in human biofluids and cell culture models, including amyloid beta itself.

26 May 2023

2023 PCRF grant recipients announced for exploring new, safer treatments for pediatric cancers

The Pediatric Cancer Research Foundation, a nonproﬁt focused on transforming pediatric cancer care by accelerating research breakthroughs, today announced the 19 recipients of its 2023 research grants.

26 May 2023

New understanding of chemotherapeutic resistance in recurring ovarian cancer

A new editorial paper was published in Oncoscience (Volume 10) on May 11, 2023, entitled, "UPR-induced ovarian cancer cell fusion: a mechanism favoring drug resistance?"

26 May 2023

Study identifies a novel druggable signaling molecule involved in obesity and diabetes

More than 40% of Americans are considered obese, and the trend continues to grow. The treatments or preventive options for obesity and obesity-associated diseases are limited.

26 May 2023

Penn State researchers create first protein-based nano-computing agent

The first protein-based nano-computing agent that functions as a circuit has been created by Penn State researchers.

26 May 2023

Research could help develop better treatments for swallowing disorders

Sensory cells in the vagus nerve can detect and locate food in the esophagus. Their signals help transport the food onward to the stomach. Signal failure leads to swallowing disorders, say a team led by Carmen Birchmeier at the Max Delbrück Center.

26 May 2023

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Several phase 3 studies conducted by researchers from Dana-Farber Cancer Institute show promising results for patients with rectal, brain, and kidney cancers. The results of these studies, along with dozens of others led by Dana-Farber researchers, will be presented at the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

26 May 2023

Hydrogen sulfide can be used to support photothermal therapy for cancer

Hydrogen sulfide is usually a highly toxic gas. However, with careful preparation, it can be used to support photothermal therapy (PTT) in treating cancer, as a team of researchers reporting in the journal Angewandte Chemie has recently discovered.

26 May 2023

Study highlights two strategies used by Salmonella to escape the human body's defenses

Like thieves that constantly look for ways to evade capture, Salmonella enterica, a disease-causing bacterium, uses various tactics to escape the human body's defence mechanisms.

26 May 2023

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Our cells are crisscrossed by a system of membrane tubes and pockets called the endoplasmic reticulum (ER). It is crucial for the production of biomolecules and is continuously built up and degraded.

26 May 2023

Fission yeast study sheds new light on gross chromosomal rearrangement

When creating a computer program, errors in the code can introduce bugs to the software. Similarly, errors in our body's genetic code, DNA, which is stored in structures known as chromosomes, can bring about mutations in the body.

26 May 2023

Treatment with luspatercept improves red blood cell counts in patients with myelodysplastic syndromes

Treatment with luspatercept improved red blood cell counts and erythroid responses compared to treatment with epoetin alfa in patients with myelodysplastic syndromes (MDS), allowing the majority to no longer require regular blood transfusions.

26 May 2023

Using nanoparticles and magnetic field to guide immunotherapy cells

A novel ideal proposed by European researchers would guide immunotherapy cells to where they are needed most.

26 May 2023

Researchers explore the possibility of treating lung cancer by targeting telomeres

Healthy cells can only divide a limited number of times during an organism's lifetime. In contrast, tumor cells are immortal: they proliferate indefinitely and uncontrollably, and this is the defining characteristic of cancer.

26 May 2023

Scientists use AI to identify new antibiotic that could fight drug-resistant infections

Using an artificial intelligence algorithm, researchers at MIT and McMaster University have identified a new antibiotic that can kill a type of bacteria that is responsible for many drug-resistant infections.

25 May 2023

Tumors in distant organs remotely reprogram the liver

Cancers often release molecules into the bloodstream that pathologically alter the liver, shifting it to an inflammatory state, causing fat buildup and impairing its normal detoxifying functions, according to a study from investigators at Weill Cornell Medicine.

25 May 2023

Cell News and Research

Modest reduction in beta-amyloidogenic processing of APP may be a viable strategy to prevent Alzheimer's disease

2023 PCRF grant recipients announced for exploring new, safer treatments for pediatric cancers

New understanding of chemotherapeutic resistance in recurring ovarian cancer

Study identifies a novel druggable signaling molecule involved in obesity and diabetes

Penn State researchers create first protein-based nano-computing agent

Research could help develop better treatments for swallowing disorders

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Hydrogen sulfide can be used to support photothermal therapy for cancer

Study highlights two strategies used by Salmonella to escape the human body's defenses

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Fission yeast study sheds new light on gross chromosomal rearrangement

Treatment with luspatercept improves red blood cell counts in patients with myelodysplastic syndromes

Using nanoparticles and magnetic field to guide immunotherapy cells

Researchers explore the possibility of treating lung cancer by targeting telomeres

Scientists use AI to identify new antibiotic that could fight drug-resistant infections

Tumors in distant organs remotely reprogram the liver

Groundbreaking study targets 'jumping genes' in the entire genomes of the human large intestine

New review unravels phthalates’ role in heart disease

Curcumin can suppress metastasis of colorectal cancer cells by activating a specific signaling pathway

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Improve fermentation and cell culture performance with real-time gas analysis eBook

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