Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Benefits of heterotypic vaccination against variants of SARS-CoV-2

A new study evaluated the antibody responses against the newly emerged SARS-CoV-2 Omicron variant upon heterotypic vaccination in animal models.

28 Mar 2022

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

A new research paper published as an early release manuscript in the Nature Medicine journal compares the sensitivity of this strain as well as the earlier Delta and the newer BA.2 to therapeutic mAbs.

27 Mar 2022

Tuberculosis infection protects mice against COVID-19

To study if prior Mtb infection affects the response to CoV2 infection, K18-hACE2 (ACE2) and C57BL/6 (B6) mice were infected with Mtb, and post thirty days, were exposed to CoV2.

27 Mar 2022

Study evaluates efficacy of sarilumab in severe/critical COVID-19 patients

Researchers discuss the results of a clinical trial to assess the efficacy and safety of IV sarilumab for the treatment of hospitalized COVID-19 patients.

27 Mar 2022

Biologists discover gene deletion behind abnormality in blood cancer cells

The mystery is being unraveled of why the control centers, or nuclei, of certain blood cancer cells have a distinctly odd shape.

27 Mar 2022

Exploring the vital connection between gut microbes, physical activity, and health

Our bowels accommodate billions of active microbes that affect the health, a fact that is arousing increasing interest also among athletes.

26 Mar 2022

Researchers discover new pathway for DNA transfer in tumor microenvironment

University of Notre Dame researchers have discovered another way tumor cells transfer genetic material to other cells in their microenvironment, causing cancer to spread.

25 Mar 2022

New method for generating binding proteins solves a long-standing challenge in drug development

A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable proteins on the surface of viruses.

25 Mar 2022

Novel SARS-CoV-2 strains found to have low impact on CD8 T lymphocytes

Researchers investigated the impact of mutations in the SARS-CoV-2 variants of interest and variants of concern on the properties of the cluster of differentiation 8 T lymphocytes.

25 Mar 2022

Study finds methylene blue is a low-micromolar inhibitor of the the SARS-CoV-2 spike protein and ACE2 interaction

A new study has focussed on screening and identification of possible SMIs of this PPI for COVID-19.

25 Mar 2022

Study explores macrophage susceptibility to SARS-CoV-2 virions

A new study investigated the susceptibility of macrophages to SARS-CoV-2 virions.

25 Mar 2022

Scientists describe use of PCR in detecting SARS-CoV-2 in paraffine-embedded tissues

Scientists compared the efficacy of the quantitative polymerase chain reaction method and immunohistochemistry in detecting SARS-CoV-2 in different human tissues.

25 Mar 2022

Topologically designed antibody candidates for SARS-CoV-2 and cancer therapies

A recent study presented topologically engineered fragment crystallizable-fusion proteins and antibodies as therapeutic options for diseases like human coronaviruses infections and cancers.

25 Mar 2022

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Researchers evaluated the neutralizing antibody titers and anti-receptor-binding domain immunoglobulin G titers in sera of kidney transplant recipients who were vaccinated against COVID-19 and treated with 300 mg dosage of Evusheld™

25 Mar 2022

Impact of truncated open reading frame 8 protein variants of SARS-CoV-2

A new study identified unique truncated open reading frame 8 proteins among SARS-CoV-2 sequences.

25 Mar 2022

Researchers characterize vaccines for infectious bronchitis virus

A new study characterized the genetic and immunological aspects of the infectious bronchitis virus (IBV) vaccines commercially used in Korea.

25 Mar 2022

Study investigates incident diabetes burden and risk in post-acute COVID-19 patients

Researchers examined the post-acute risk and burden of incident diabetes beyond the initial 30 days of COVID-19.

25 Mar 2022

CASCADE biosensor found to be effective in naked-eye SARS-CoV-2 RNA detection

Researchers reported the efficacy of their self-developed CASCADE biosensor in naked-eye detection of SARS-CoV-2 RNA using gold nanoparticles.

25 Mar 2022

Study indicates combining a hydrogen peroxide-based disinfectant with cellulosic copper nanoparticles lowers human coronaviruses' infectivity

A recent study indicated that combining a hydrogen peroxide-based disinfectant and cellulosic copper nanoparticles lowered human coronaviruses' infectivity.

25 Mar 2022

Model for investigating the effect of mutations on the binding affinity of the SARS-CoV-2 RBD-ACE2 complex

Researchers used a CNN regression model to investigate the effect of mutations on the binding affinity of the SARS-CoV-2 RBD-ACE2 complex.

25 Mar 2022

Protein News and Research

Further Reading

Benefits of heterotypic vaccination against variants of SARS-CoV-2

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

Tuberculosis infection protects mice against COVID-19

Study evaluates efficacy of sarilumab in severe/critical COVID-19 patients

Biologists discover gene deletion behind abnormality in blood cancer cells

Exploring the vital connection between gut microbes, physical activity, and health

Researchers discover new pathway for DNA transfer in tumor microenvironment

New method for generating binding proteins solves a long-standing challenge in drug development

Novel SARS-CoV-2 strains found to have low impact on CD8 T lymphocytes

Study finds methylene blue is a low-micromolar inhibitor of the the SARS-CoV-2 spike protein and ACE2 interaction

Study explores macrophage susceptibility to SARS-CoV-2 virions

Scientists describe use of PCR in detecting SARS-CoV-2 in paraffine-embedded tissues

Topologically designed antibody candidates for SARS-CoV-2 and cancer therapies

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Impact of truncated open reading frame 8 protein variants of SARS-CoV-2

Researchers characterize vaccines for infectious bronchitis virus

Study investigates incident diabetes burden and risk in post-acute COVID-19 patients

CASCADE biosensor found to be effective in naked-eye SARS-CoV-2 RNA detection

Study indicates combining a hydrogen peroxide-based disinfectant with cellulosic copper nanoparticles lowers human coronaviruses' infectivity

Model for investigating the effect of mutations on the binding affinity of the SARS-CoV-2 RBD-ACE2 complex

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