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Pembrolizumab combination therapies effective for advanced NSCLC, study shows

While pembrolizumab is an approved treatment for patients with stage III non-small cell lung cancer (NSCLC), only some patients respond to this therapy. Treatment failure, researchers say, is often caused by differences in the tumor microenvironment.

12 Jul 2023

Mitochondrial impairment, not inflammation, may be main driver of Gulf War Illness symptoms

Gulf War Illness (GWI) is a chronic multisymptom health condition affecting one-third of all veterans who served in the 1991 Gulf War, most of whom remain afflicted more than 30 years later.

12 Jul 2023

Cetuximab plus radiotherapy effective in treating locally advanced cutaneous squamous cell cancer

A new research paper was published in Oncotarget's Volume 14 on July 7, 2023, entitled, "Effectiveness and toxicity of cetuximab with concurrent RT in locally advanced cutaneous squamous cell skin cancer: a case series."

12 Jul 2023

Self-reported long COVID symptoms not identified in diagnostic tests

Researchers describe chronic symptoms related to physical or mental functioning following SARS-CoV-2 infection.

12 Jul 2023

Novel vaccine against Lyme disease reported to be safe and effective

Researchers determine the safety and immunogenicity of a novel candidate vaccine against Lyme borreliosis.

11 Jul 2023

Fibromyalgia patients may be at increased risk of death

Fibromyalgia, a condition that causes persistent widespread pain and fatigue, may be linked to a heightened risk of death as a result of vulnerability to accidents, infections, and especially suicide, suggests a pooled data analysis of the available evidence, published in the open access journal RMD Open.

10 Jul 2023

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis. William G. Powderly, MD, (right) who led the large clinical trial, discusses patient conditions with Maanasi Samant, MD, in the intensive care unit at Barnes-Jewish Hospital, one of the major trial sites, during the COVID-19 pandemic.

10 Jul 2023

Moderna provides an update on regulatory submissions for RSV vaccine candidate, mRNA-1345

Moderna, Inc., a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, today provided an update on regulatory submissions for mRNA-1345, a vaccine for the prevention of RSV-associated lower respiratory tract disease (RSV-LRTD) and acute respiratory disease (ARD) in adults aged 60 years or older.

10 Jul 2023

The vital role of smartphone apps during the COVID-19 pandemic

At the start of the coronavirus disease 2019 (COVID-19) pandemic, analog techniques like nasopharyngeal swab specimens for polymerase chain reaction (PCR) testing were prominent. The widespread use of nonpharmaceutical interventions (NPIs) such as facemasks and social distancing was reminiscent of the influenza outbreak in 1918.

9 Jul 2023

Unique blood protein patterns in long COVID patients could reveal potential drug targets

Recently published in The Journal of Translational Medicine, a team at Lawson Health Research Institute has discovered unique patterns of blood plasma proteins in patients with long COVID that could reveal potential drug targets to improve patient outcomes.

7 Jul 2023

Review: Patient aggression towards receptionists is a serious workplace safety concern

Patient aggression towards receptionists working in general practice is a "serious workplace safety concern," concludes a review of the available published evidence, published in the open access journal Family Medicine and Community Health.

6 Jul 2023

Women with post-acute sequelae of COVID-19 could be at greater risk of developing hypertension

Post-acute sequelae of COVID-19 (PASC), colloquially referred to as long COVID-19 or long COVID, is when someone recovers from acute COVID-19 but shows a cluster of symptoms for months afterward.

4 Jul 2023

Immune inflammatory reaction to COVID-19 may not be the underlying cause of long Covid

Long Covid, which affects nearly two-million people in the UK, is not caused by an immune inflammatory reaction to COVID-19, University of Bristol-led research finds.

4 Jul 2023

New regulatory system discovered in malaria parasite

Gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum, is regulated by melatonin (the circadian signaling hormone) in host blood, and intrinsic parasite cues, via a factor called ApSigma, as identified by a recent study aided by Tokyo Tech's World Research Hub Initiative.

3 Jul 2023

Long work hours and poor work-life balance threaten health of Singapore's young professionals

Long work hours among young adults hinder healthy behaviors, impacting population health. Understanding these barriers is crucial for targeted health promotion efforts.

2 Jul 2023

Smidt Heart Institute patient plans to climb Peru's Machu Picchu after successful robotic surgery

The summit is a good place to be

1 Jul 2023

Study identifies the predictors of post-coronavirus disease 2019 (COVID-19) syndrome symptoms

Study identifies the predictors of post-coronavirus disease 2019 (COVID-19) syndrome symptoms.

30 Jun 2023

Beyond diagnosis: coping strategies and their influence on Parkinson's patients' well-being

Researchers determined the predictors of particular coping methods used by Parkinson's Disease (PD).

30 Jun 2023

New drug effective as a treatment against ulcerative colitis, clinical trial shows

A new drug, investigated by Amsterdam UMC together with colleagues around the world, is effective as a treatment against ulcerative colitis.

28 Jun 2023

High BMI linked to increased risk of 5 rheumatic diseases

A new study by Uppsala University shows that a higher body mass index (BMI) increases the risk of five different rheumatic diseases: rheumatism, osteoarthritis, gout, psoriatic arthritis and inflammatory spondylitis. The researchers also noted that BMI was a stronger risk factor for women compared to men in terms of gout and psoriatic arthritis. The study will be presented in the journal Arthritis & Rheumatology.

26 Jun 2023

Fatigue News and Research

Pembrolizumab combination therapies effective for advanced NSCLC, study shows

Mitochondrial impairment, not inflammation, may be main driver of Gulf War Illness symptoms

Cetuximab plus radiotherapy effective in treating locally advanced cutaneous squamous cell cancer

Self-reported long COVID symptoms not identified in diagnostic tests

Novel vaccine against Lyme disease reported to be safe and effective

Fibromyalgia patients may be at increased risk of death

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Moderna provides an update on regulatory submissions for RSV vaccine candidate, mRNA-1345

The vital role of smartphone apps during the COVID-19 pandemic

Unique blood protein patterns in long COVID patients could reveal potential drug targets

Review: Patient aggression towards receptionists is a serious workplace safety concern

Women with post-acute sequelae of COVID-19 could be at greater risk of developing hypertension

Immune inflammatory reaction to COVID-19 may not be the underlying cause of long Covid

New regulatory system discovered in malaria parasite

Long work hours and poor work-life balance threaten health of Singapore's young professionals

Smidt Heart Institute patient plans to climb Peru's Machu Picchu after successful robotic surgery

Study identifies the predictors of post-coronavirus disease 2019 (COVID-19) syndrome symptoms

Beyond diagnosis: coping strategies and their influence on Parkinson's patients' well-being

New drug effective as a treatment against ulcerative colitis, clinical trial shows

High BMI linked to increased risk of 5 rheumatic diseases

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