Low Density Lipoprotein (LDL) News and Research

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Course of injections in childhood might help protect people from heart disease later in life

A course of injections in childhood might help protect people from heart disease later in life. And for those whose arteries are already clogged up, a dose of antibodies could provide immediate benefits. That's the enticing vision raised by animal studies.

26 Dec 2004

New way to reduce fat and cholesterol levels in the body

Just in time for the holidays, McGill researchers have identified a new way to reduce fat and cholesterol levels in the body. Their program, which combines consuming plant-derived sterols (or oils) with exercise, may benefit those who are at risk of coronary heart disease.

21 Dec 2004

Israeli developed fruit called pomelit, lowers blood cholesterol

People who eat the Israeli-developed fruit known in Hebrew as pomelit (a cross between a grapefruit and a pomelo) or drink its juice regularly will be able to lower their blood cholesterol and increase their blood antioxidant activity, thus improving their chances of preventing blocked heart arteries and heart attacks, says a researcher at the Hebrew University of Jerusalem.

30 Nov 2004

Stress affects molecules believed to play a key role in cellular aging

There have been many studies that have shown that your health is greatly affected by how you react to stressful events in life-setbacks or deadlines at work, conflicts and losses at home.

29 Nov 2004

Chylomicrons may be as dangerous or more dangerous than low-density lipoprotein (LDL) cholesterol

You may not yet have heard of chylomicrons, but a nutritional scientist at the University of Alberta believes you will soon--especially if you care about preventing a stroke or heart attack.

24 Nov 2004

Four major U.S. ethnic groups less likely to have cholesterol controlled

Compared with non-Hispanic whites, non-Hispanic blacks and Hispanics who qualify for cholesterol-lowering drug treatment are less likely to have their “bad” LDL cholesterol controlled to recommended levels, researchers reported at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Zetia co-administered with Fenofibrate significantly reduced LDL ("bad") cholesterol in mixed hyperlipidemia patients

Results from a new study showed that coadministration of Zetia (ezetimibe) and fenofibrate significantly reduced LDL ("bad") cholesterol (LDL-C), non-high density lipoprotein cholesterol (non-HDL-C) and apo B1 in patients with mixed hyperlipidemia and high LDL cholesterol when compared to fenofibrate alone.

9 Nov 2004

ACE inhibitors not needed for many heart disease patients

Many heart disease patients who are already receiving state-of-the-art therapy do not benefit from additional treatment with angiotensin converting enzyme (ACE) inhibitors, according to results of a new study funded by the National Heart, Lung, and Blood Institute (NHLBI).

8 Nov 2004

Generic statin drugs shown to produce similar or better results than expensive brand-name drugs

Researchers from Kaiser Permanente's Northern California region are presenting a study at this week's American Heart Association Scientific Sessions showing that patients who use a generic statin drug rather than its brand-name equivalent fared as well as- sometimes better than-patients on the more expensive drug.

8 Nov 2004

Walnut supplementation favorably affects cholesterol and other lipids that are signs of cardiovascular risk

A Penn State study has shown that a diet rich in alpha-linolenic acid from walnuts, walnut oil and flaxseed oil not only lowered bad cholesterol but also decreased markers for blood vessel inflammation in men and women representative of typical Americans at cardiovascular risk.

8 Nov 2004

Lipid Sciences' selective delipidation process demonstrates enhanced ability in removing cholesterol from cells

Lipid Sciences announced today that researchers have successfully used the Company's proprietary "selective delipidation" process to create a modified form of HDL ("good cholesterol") that is known to be more effective in reverse cholesterol transport, the body's natural process for removing lipids from arterial plaque.

8 Nov 2004

Landmark case challenges safety of Atkins diet

West Palm Beach County Court Judge Susan Lubitz ruled today that the landmark lawsuit filed by former Atkins dieter and Florida businessman Jody Gorran will go forward.

3 Nov 2004

High-dose statin therapy for aggressive cholesterol-lowering outperforms typical care

Patients treated with high doses of atorvastatin had about a one percent lower annual rate of heart attacks than similar patients receiving usual care, according to a new study in the Nov. 2, 2004 issue of the Journal of the American College of Cardiology.

2 Nov 2004

Gene variations explain why people with type 2 diabetes are at much greater risk for coronary artery disease

New studies by an international team of scientists led by Joslin Diabetes Center have found variations in a gene that help explain why people with type 2 diabetes are at much greater risk for coronary artery disease, the leading cause of death for this group.

21 Oct 2004

Study increases likelihood that MRI could be used as predictive technology to determine which patients should be placed on statin therapy for atherosclerosis

Using modified magnetic resonance imaging (MRI) techniques, researchers at Johns Hopkins have been able to detect the early benefits of a cholesterol-lowering medication much sooner than before.

11 Oct 2004

Lipid profile differences explain why two people with the same overall cholesterol level can have different degrees of cardiovascular disease

When it comes to lipid profiles -- a key measure of heart disease risk-- it appears that African-Americans and women have it better than whites and men, according to a new study by Duke University Medical Center researchers.

7 Oct 2004

Sibling history is a better predictor of coronary heart disease than parental history or traditional risk factor scoring

Researchers at Johns Hopkins have found that sibling history -- whether or not a brother or sister had early heart disease -- is a better predictor of a person's likelihood of developing coronary heart disease than parental history or traditional risk factor scoring.

4 Oct 2004

Hibiscus flowers contain antioxidants that help control cholesterol levels

Hibiscus flower extract may have the same health benefits as red wine and tea according to new research by scientists in Taiwan. Hibiscus contains antioxidants that help control cholesterol levels and reduce heart disease, says the research in Journal of the Science of Food and Agriculture.

14 Sep 2004

Ezetrol co-administration with statin therapy lowers LDL cholesterol in diabetics

Results from two new clinical trials show that patients with diabetes and metabolic syndrome who are treated with ezetimibe (EZETROL®) co-administered with a statin experience greater reductions in LDL (“bad”) cholesterol, compared to patients taking a statin alone.

7 Sep 2004

Early use of aggressive statin therapy may offer some benefit for coronary patients

Statins initiated early after a patient experiences an acute coronary syndrome (ACS) event at dosages above the typical starting dose may help reduce subsequent cardiovascular events, but the high dose regimen used may increase the risk for muscle-related complications, according to the results from the Phase Z portion of the A to Z Trial released on the JAMA website today.

30 Aug 2004

Low Density Lipoprotein (LDL) News and Research

Course of injections in childhood might help protect people from heart disease later in life

New way to reduce fat and cholesterol levels in the body

Israeli developed fruit called pomelit, lowers blood cholesterol

Stress affects molecules believed to play a key role in cellular aging

Chylomicrons may be as dangerous or more dangerous than low-density lipoprotein (LDL) cholesterol

Four major U.S. ethnic groups less likely to have cholesterol controlled

Zetia co-administered with Fenofibrate significantly reduced LDL ("bad") cholesterol in mixed hyperlipidemia patients

ACE inhibitors not needed for many heart disease patients

Generic statin drugs shown to produce similar or better results than expensive brand-name drugs

Walnut supplementation favorably affects cholesterol and other lipids that are signs of cardiovascular risk

Lipid Sciences' selective delipidation process demonstrates enhanced ability in removing cholesterol from cells

Landmark case challenges safety of Atkins diet

High-dose statin therapy for aggressive cholesterol-lowering outperforms typical care

Gene variations explain why people with type 2 diabetes are at much greater risk for coronary artery disease

Study increases likelihood that MRI could be used as predictive technology to determine which patients should be placed on statin therapy for atherosclerosis

Lipid profile differences explain why two people with the same overall cholesterol level can have different degrees of cardiovascular disease

Sibling history is a better predictor of coronary heart disease than parental history or traditional risk factor scoring

Hibiscus flowers contain antioxidants that help control cholesterol levels

Ezetrol co-administration with statin therapy lowers LDL cholesterol in diabetics

Early use of aggressive statin therapy may offer some benefit for coronary patients

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