Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Expansion stress promotes aggressive tumor cell growth in breast cancer

Expansion stress can have an alarming impact on breast cancer cells by creating conditions that could lead to dangerous acceleration of the disease, an interdisciplinary team of University of Alabama at Birmingham researchers has found.

9 Jul 2020

Breast cancer cells can reprogram natural killer cells to aid in metastasis

Natural killer cells, a type of immune cell, are known to limit metastasis by inducing the death of cancer cells. But metastases still form in patients, so there must be ways for cancer cells to escape.

9 Jul 2020

Researchers propose novel approach to limit life-threatening complications related to COVID-19

Patients with severe COVID-19 frequently experience a life-threatening immune reaction, sometimes called a cytokine storm, which can lead to respiratory failure, organ damage and potentially death.

8 Jul 2020

Scientists introduce a new approach for immunological tumor treatment

Our immune system ought to be able to recognize and kill tumor cells. However, many tumors deceive the immune system.

8 Jul 2020

CNIO’s collaborative platform simplifies research on brain metastasis

Science is collaborative by nature, since scientific knowledge only advances, step by step, through combined efforts and findings. Nevertheless, there is often a lack of communication regarding the more technical and everyday advances in laboratory work, and as a result research progresses less quickly.

8 Jul 2020

Novel mechanism regulates planar cell polarity crucial for organ function

Planar cell polarity (PCP), a process in which the epithelial tissues are polarized within the plane of the epithelium, plays an important role in development and organ function.

8 Jul 2020

Researchers develop bioprinted skin model of cutaneous squamous cell carcinoma

The cover for issue 27 of Oncotarget features "Bimodal imaging examples of control and treated tumors (red) before and after the treatment period," by Browning, et al. and reported that the authors developed a 3-dimensional bioprinted skin model of cutaneous squamous cell carcinoma (cSCC) tumors together with a microscopy assay to test chemotherapeutic effects in tissue.

7 Jul 2020

New assay uses unique fluorescent tags to analyze multiple cell populations

An efficient, robust method of examining the interactions between cells uses fluorescent tagging to simultaneously analyze multiple cell populations, speeding up a once tedious and limiting process.

6 Jul 2020

Moffitt researchers discover key protein involved in cancer metastasis

Cancer is complex and unpredictable. Despite successful treatment or years of remission, there is always a chance that a patient's cancer can return.

6 Jul 2020

Newly discovered endometrial cancer biomarker enables early detection and treatment

A newly discovered endometrial (uterine) cancer biomarker and diagnostic method will enable detection of the tumor type that is likely to spread and recur so that clinicians can initiate treatment early and stop the cancer from attacking other parts of the body.

3 Jul 2020

Inflammatory changes in tumors can cause drug resistance in cancer blood vessels

Scientists at Hokkaido University and collaborators have identified how inflammatory changes in tumors caused by chemotherapy trigger blood vessel anomalies and thus drug-resistance, resulting in the poor prognosis of cancer patients.

1 Jul 2020

New radiopharmaceutical shows excellent imaging performance in tumor detection

For neuroendocrine cancer patients with liver metastases, a new radiopharmaceutical, 68Ga-DOTA-JR11, has shown excellent imaging performance in tumor detection, staging, and restaging, providing important information to guide treatment.

26 Jun 2020

Research reveals new insights into molecular circuitry controlling cancer growth and spread

Research led by Queen Mary University of London has revealed novel insights into the molecular circuitry controlling cancer cell growth and spread.

23 Jun 2020

Improving cancer therapies by exploiting drug resistance in cancer

News-Medical talks to Professor David Thomas about his recent research identifying the mechanisms behind cancer cells developing resistance to drugs.

23 Jun 2020

New technology detects breast cancer using tears

Kobe University and System Instruments Co., Ltd. researchers have developed TearExo; new technology to detect breast cancer using the exosomes found in tears as biomarkers. Exosomes are a subtype of extracellular vesicles.

19 Jun 2020

Two potent small molecules appear to suppress tumor growth in multiple cancers

City of Hope scientists have identified and developed two potent small molecules that appear to suppress tumor growth in multiple cancers even when other treatments cease to work, possibly due to the development of drug resistance.

16 Jun 2020

Common cholesterol drugs could slow breast cancer metastasis to the brain

A new study from the University of Notre Dame shows drugs used to treat high cholesterol could interfere with the way breast cancer cells adapt to the microenvironment in the brain, preventing the cancer from taking hold.

16 Jun 2020

Abnormal expression of Zeb2 protein in epithelial cells can induce colorectal cancer

A collaborative study by research groups from the VIB-UGent Center for Inflammation Research and Ghent University uncovered a new mechanism causing colorectal cancer.

16 Jun 2020

Accelerating the Diagnosis and Treatment of Cancer with Mass-Spectrometry Based Techniques

An interview with Livia Eberlin, Assistant Professor at the University of Texas at Austin, discussing the development of mass-spectrometry based techniques for cancer diagnosis and improved clinical outcomes.

From Pittcon 16 Jun 2020

Damon Runyon Cancer Research Foundation awards $3.2 million to early-career physician-scientists

The Damon Runyon Cancer Research Foundation has named four new Damon Runyon Clinical Investigators.

12 Jun 2020

Metastasis News and Research

Further Reading

Expansion stress promotes aggressive tumor cell growth in breast cancer

Breast cancer cells can reprogram natural killer cells to aid in metastasis

Researchers propose novel approach to limit life-threatening complications related to COVID-19

Scientists introduce a new approach for immunological tumor treatment

CNIO’s collaborative platform simplifies research on brain metastasis

Novel mechanism regulates planar cell polarity crucial for organ function

Researchers develop bioprinted skin model of cutaneous squamous cell carcinoma

New assay uses unique fluorescent tags to analyze multiple cell populations

Moffitt researchers discover key protein involved in cancer metastasis

Newly discovered endometrial cancer biomarker enables early detection and treatment

Inflammatory changes in tumors can cause drug resistance in cancer blood vessels

New radiopharmaceutical shows excellent imaging performance in tumor detection

Research reveals new insights into molecular circuitry controlling cancer growth and spread

Improving cancer therapies by exploiting drug resistance in cancer

New technology detects breast cancer using tears

Two potent small molecules appear to suppress tumor growth in multiple cancers

Common cholesterol drugs could slow breast cancer metastasis to the brain

Abnormal expression of Zeb2 protein in epithelial cells can induce colorectal cancer

Accelerating the Diagnosis and Treatment of Cancer with Mass-Spectrometry Based Techniques

Damon Runyon Cancer Research Foundation awards $3.2 million to early-career physician-scientists

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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