Microscopy News and Research

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HKU research advances understanding of the fundamental biological processes of gene regulation

A research team from the University of Hong Kong led by Professor Xiang David Li from the Department of Chemistry in collaboration with Dr Yuanliang Zhai from the HKU School of Biological Sciences and Dr Jason Wing Hon Wong and Dr Xiucong Bao from the HKU School of Biomedical Sciences recently made a key breakthrough in understanding how genetic information encoded in our DNA is 'read' and why errors in 'reading' such information can often lead to developmental defects or cancers.

20 Feb 2023

Structure of DREADD designer receptor could pave the way for creating next generation tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells.

20 Feb 2023

In-depth assessment of muscle biopsies in patients with long COVID

Researchers analyzed skeletal muscle biopsies of patients with persistent fatigue and malaise post-exertion to determine the underlying mechanisms of long COVID.

20 Feb 2023

Using AI to follow cell movement across time and space

The enormous amount of data obtained by filming biological processes using a microscope has previously been an obstacle for analyses.

16 Feb 2023

Understanding neural crest cell development will help to better comprehend craniofacial birth defects

Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations.

16 Feb 2023

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Electrochemical method helps to continuously witness and analyze details of protein folding

Scientists are not yet clear on how the tau protein changes from a benign protein essential for normal function in our brains into the toxic neurofibrillary tangles that are a signature of Alzheimer's and other neurodegenerative diseases.

15 Feb 2023

New method provides important insights into the development of epilepsy

In epilepsy research, it has long been assumed that a leaky blood-brain barrier is a cause of inflammation in the brain.

13 Feb 2023

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Researchers developed spherical hydrogel inhalation for enhanced lung defense to protect against SARS-CoV-2 infections.

13 Feb 2023

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Researchers found that LRRC15, a TLR-related cell surface receptor, blocked SARS-CoV-2 spike binding.

13 Feb 2023

Active compound from edible mushrooms boosts nerve growth and enhances memory

Researchers from The University of Queensland have discovered the active compound from an edible mushroom that boosts nerve growth and enhances memory.

10 Feb 2023

High-precision mechanical sensing system can measure in vivo biomechanical properties of tissue, single cell

Fiber sensing scientists at Shenzhen University have developed a compact fiber optical nanomechanical probe (FONP) for measuring in vivo biomechanical properties of tissue and even single cell.

10 Feb 2023

Study demonstrates antiviral effects of vinegar against SARS-CoV-2

A study published in the journal PLOS ONE demonstrates the effectiveness of acetic acid, the main component of vinegar, in inactivating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Feb 2023

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

Researchers analyze prophages of the LF82 strain of adherent-invasive Escherichia coli to better understand their behavior in vitro and within macrophages.

8 Feb 2023

Cryo-EM provides new insights into the structure of the centromeric region

The genetic material inside cells is organized into structures called chromosomes. The centromere is essential for the correct division of the chromosomes via interaction with spindle microtubules when cells divide and grow.

6 Feb 2023

New insights into the release of microplastics from breastmilk storage bags

Researchers from China analyzed the quantity, size, and composition of microplastics and other particle matter released into breastmilk from disposable breastmilk storage bags.

6 Feb 2023

Penn scientists discover a cellular pathway that keeps Ebola virus from exiting human cells

In their evolutionary battle for survival, viruses have developed strategies to spark and perpetuate infection. Once inside a host cell, the Ebola virus, for example, hijacks molecular pathways to replicate itself and eventually make its way back out of the cell into the bloodstream, where it can spread further.

3 Feb 2023

Microscopy News and Research

HKU research advances understanding of the fundamental biological processes of gene regulation

Structure of DREADD designer receptor could pave the way for creating next generation tools

In-depth assessment of muscle biopsies in patients with long COVID

Using AI to follow cell movement across time and space

Understanding neural crest cell development will help to better comprehend craniofacial birth defects

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Electrochemical method helps to continuously witness and analyze details of protein folding

New method provides important insights into the development of epilepsy

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Active compound from edible mushrooms boosts nerve growth and enhances memory

High-precision mechanical sensing system can measure in vivo biomechanical properties of tissue, single cell

Study demonstrates antiviral effects of vinegar against SARS-CoV-2

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

Cryo-EM provides new insights into the structure of the centromeric region

New insights into the release of microplastics from breastmilk storage bags

Penn scientists discover a cellular pathway that keeps Ebola virus from exiting human cells

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

The human body develops strategies to prevent the immune response from overshooting its mark

Microscopic technique enables real-time study of RNA G-quadruplexes in living cells

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Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo