Steroid News and Research

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Steroid receptor gene variant impacts metabolic health

A variant in the glucocorticoid receptor gene may be associated with increased body fat and insulin resistance, show study findings.

10 Jul 2012

Questionnaire may aid rheumatoid arthritis flare diagnosis

French researchers have created a 13-item patient-administered questionnaire for identifying a recent or present rheumatoid arthritis flare.

9 Jul 2012

Enrollment complete in Lux Biosciences Luveniq Phase 3 study for non-infectious uveitis

Lux Biosciences, Inc. today announced the completion of patient enrollment in its Phase 3 clinical study of Luveniq (oral voclosporin) for the treatment of non-infectious uveitis. Lux Biosciences anticipates that data from the Phase 3 study will be available early in the first quarter of 2013.

9 Jul 2012

Ampio announces results from Optina trial on DME

Ampio Pharmaceuticals, Inc., a biopharmaceutical company developing innovative proprietary drugs for inflammation, eye disease, kidney disease, CNS disease, metabolic disease and male sexual dysfunction and conducting clinical trials on its three lead drugs (Ampion, Optina & Zertane), announced the significant results from their further analysis of its Optina trial on DME.

9 Jul 2012

Imaging PR status may help identify tumor response to endocrine therapy

Research published in the July issue of The Journal of Nuclear Medicine shows imaging progesterone receptor (PR) status also may be able to identify responders and nonresponders to endocrine therapy at an early stage.

3 Jul 2012

Study suggests adverse role for BclI polymorphism in obesity and insulin resistance

A large study in people at risk of diabetes has found a direct association between the presence of a small genetic alteration in a hormone receptor and increased body fat and insulin resistance. The results, to be presented Tuesday at The Endocrine Society's 94th Annual Meeting in Houston, suggest an adverse role for a previously described genetic variant, the BclI polymorphism.

28 Jun 2012

New tissue-culture study: Fungicide can induce insulin resistance

A fungicide used on farm crops can induce insulin resistance, a new tissue-culture study finds, providing another piece of evidence linking environmental pollutants to diabetes. The results will be presented Saturday at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

Low DHEA-S levels may increase risk of heart and blood-vessel disease in elderly men

Low levels of a naturally occurring steroid are associated with an increased risk of heart and blood-vessel disease in elderly men, a new study finds. The results will be presented Saturday at The Endocrine Society's 94th Annual Meeting in Houston.

25 Jun 2012

Colectomy need in patients with severe ulcerative colitis drastically reduced by Kappaproct

InDex Pharmaceuticals today announced the publication of positive data from the Company's compassionate use program with its lead compound Kappaproct.

19 Jun 2012

Exercise-related hormones do not play an influential role in building muscle

New research from scientists at McMaster University reveals exercise-related testosterone and growth hormone do not play an influential role in building muscle after weightlifting, despite conventional wisdom suggesting otherwise.

15 Jun 2012

ORMC offers bronchial thermoplasty for severe asthma

Doctors at Orlando Regional Medical Center (ORMC) are delivering heat directly to the source to treat patients with severe asthma - a respiratory disease that causes the airways in the lungs to narrow, making it difficult to breathe.

13 Jun 2012

Ampio’s CRO completes Optina clinical trial for DME

Ampio Pharmaceuticals, Inc., a clinical stage biopharmaceutical company, whose lead drugs treat inflammatory diseases, including osteoarthritis and complications of Diabetes Mellitus such as diabetic macular edema (and others) announced today that it's CRO has completed analysis of the primary end point in the Optina clinical trial for DME conducted at St Michael Diabetes Hospital in Toronto Canada.

11 Jun 2012

Steroids may slow progression of life-threatening skin reactions

Multi-national study results show that the progression of Steven Johnson Syndrome or Toxic Epidermal Necrolysis may be lengthened if corticosteroids are used prior to the onset of either condition.

8 Jun 2012

Takeda announces updated results from orteronel phase 2 study on nmCRPC

Millennium: The Takeda Oncology Company with its parent company Takeda Pharmaceutical Company Limited today announced updated results from a phase 2 study of orteronel, a selective oral 17,20 lyase inhibitor, dosed without prednisone in patients with non-metastatic castration resistant prostate cancer (nmCRPC) and rising prostate-specific antigen.

5 Jun 2012

UH CNRCS students achieve significant milestones in cancer therapy research

Four University of Houston (UH) students are well on their way to emerging cancer research careers upon achieving significant milestones this spring in their work toward new therapies for prostate and breast cancer.

2 Jun 2012

Glucocorticoid steroids in intelligent medicine specifically hits relevant cells

Scientists at Aarhus University, Denmark in collaboration with the biotech company Cytoguide now publish a key to use glucocorticoid steroids in a kind of intelligent medicine that specifically hits the relevant cells. Data are based on rodent studies but if this principle is translated to humans it may greatly improve todays hazardous treatment with this type of potent steroids.

1 Jun 2012

Osteopenia/osteoporosis more prevalent among male patients with pulmonary disease

There is a very high prevalence of osteopenia/osteoporosis among male patients with pulmonary disease, according to a new study from researchers in California.

21 May 2012

Studies show vitamin D may benefit cardiovascular, skin and metabolic disorders

The Endocrine Society's new scientific statement published online today represents the first comprehensive evaluation of both the basic and clinical evidence related to the non-skeletal effects of vitamin D. The statement addresses current research regarding the associations of vitamin D with immune function, hypertension, stroke, skin conditions and maternal/fetal health.

19 May 2012

Abiraterone acetate can help eliminate prostate tumors

A hormone-depleting drug approved last year for the treatment of metastatic prostate cancer can help eliminate or nearly eliminate tumors in many patients with aggressive cancers that have yet to spread beyond the prostate, according to a clinical study to be presented at the annual meeting of the American Society of Clinical Oncology (ASCO), June 1-5, in Chicago.

17 May 2012

Sorin launches full portfolio of pacing, defibrillation and left ventricular leads

Sorin Group, a global medical device company and a leader in the treatment of cardiovascular diseases, announced today at Heart Rhythm 2012, the Heart Rhythm Society's 33rd Annual Scientific Sessions, FDA approval and commercial launch for a full portfolio of pacing, defibrillation and left ventricular leads.

11 May 2012

Steroid News and Research

Steroid receptor gene variant impacts metabolic health

Questionnaire may aid rheumatoid arthritis flare diagnosis

Enrollment complete in Lux Biosciences Luveniq Phase 3 study for non-infectious uveitis

Ampio announces results from Optina trial on DME

Imaging PR status may help identify tumor response to endocrine therapy

Study suggests adverse role for BclI polymorphism in obesity and insulin resistance

New tissue-culture study: Fungicide can induce insulin resistance

Low DHEA-S levels may increase risk of heart and blood-vessel disease in elderly men

Colectomy need in patients with severe ulcerative colitis drastically reduced by Kappaproct

Exercise-related hormones do not play an influential role in building muscle

ORMC offers bronchial thermoplasty for severe asthma

Ampio’s CRO completes Optina clinical trial for DME

Steroids may slow progression of life-threatening skin reactions

Takeda announces updated results from orteronel phase 2 study on nmCRPC

UH CNRCS students achieve significant milestones in cancer therapy research

Glucocorticoid steroids in intelligent medicine specifically hits relevant cells

Osteopenia/osteoporosis more prevalent among male patients with pulmonary disease

Studies show vitamin D may benefit cardiovascular, skin and metabolic disorders

Abiraterone acetate can help eliminate prostate tumors

Sorin launches full portfolio of pacing, defibrillation and left ventricular leads

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