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Research offers clues on why pregnancy may raise risk of organ transplant rejection

A research study at the University of Chicago has found that in pregnancy, while the T cell response to a fetus becomes tolerant to allow for successful pregnancy, the part of the immune system that produces antibodies (known as the humoral response) becomes sensitized, creating memory B cells that can later contribute to the rejection of a transplanted organ.

4 Jan 2021

USF researchers discover promising new compound to open constricted airways

Despite the progress made in managing asthma and chronic obstructive pulmonary disease (COPD), poorly controlled symptoms for both respiratory diseases can lead to severe shortness of breath, hospitalizations or even death.

4 Jan 2021

Machine-learning method can crunch data to find new uses for existing drugs

Scientists have developed a machine-learning method that crunches massive amounts of data to help determine which existing medications could improve outcomes in diseases for which they are not prescribed.

4 Jan 2021

New analysis finds no benefit in providing supplemental oxygen to mothers during childbirth

Babies who suffer oxygen deficiencies during birth are at risk of brain damage that can lead to developmental delays, cerebral palsy and even death.

4 Jan 2021

People with detectable brown fat less likely to suffer cardiac and metabolic conditions

Brown fat is that magical tissue that you would want more of. Unlike white fat, which stores calories, brown fat burns energy and scientists hope it may hold the key to new obesity treatments.

4 Jan 2021

Smoking traditional cigarettes along with e-cigarettes causes harmful health effects

Smoking traditional cigarettes in addition to using e-cigarettes results in harmful health effects similar to smoking cigarettes exclusively, according to new research published today in the American Heart Association's flagship journal Circulation.

4 Jan 2021

Higher hemoglobin threshold does not improve outcomes in preterm infants

Very low birthweight infants are at a high risk for anemia and often need blood transfusions to survive. Some doctors use a higher level and some use a lower level of red blood cells to order a transfusion.

4 Jan 2021

New cell therapy can boost immunotherapy against breast cancer

Boosting immune system T cells to effectively attack solid tumors, such as breast cancers, can be done by adding a small molecule to a treatment procedure called chimeric antigen receptor-T (CAR-T) cell therapy, according to a study by researchers at the UNC Lineberger Comprehensive Cancer Center.

4 Jan 2021

Scientists discover cell responsible for triggering chronic, low-level inflammation in fat tissue

When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with obesity.

4 Jan 2021

FDA-approved COVID-19 drug should be used cautiously, says UC researcher

While the world has its eyes on vaccines to stop the spread of coronavirus, therapeutics are still necessary to treat hospitalized patients. One of these treatments, remdesivir, is the first and only antiviral agent of its kind that the U.S. Food and Drug Administration (FDA) has approved so far for COVID-19.

3 Jan 2021

Brain damage is not caused by direct COVID-19 attack, indicates study

n an in-depth study of how COVID-19 affects a patient's brain, National Institutes of Health researchers consistently spotted hallmarks of damage caused by thinning and leaky brain blood vessels in tissue samples from patients who died shortly after contracting the disease.

3 Jan 2021

New UCLA-developed device transfers mitochondria into 100,000 or more recipient cells

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells.

29 Dec 2020

Stopping RAS inhibitors linked to risk of adverse outcomes in patients with chronic kidney disease

Small studies have suggested that a group of medications called RAS inhibitors may be harmful in persons with advanced chronic kidney disease, and physicians therefore often stop the treatment in such patients.

29 Dec 2020

FDA approves first generic glucagon for injection to treat severe hypoglycemia

Today, the U.S. Food and Drug Administration approved the first generic of glucagon for injection USP, 1 mg/vial packaged in an emergency kit, for the treatment of severe hypoglycemia (very low blood sugar), which may occur in patients with diabetes mellitus.

28 Dec 2020

Heart transplantations: Larger case volumes correlate with higher survival probabilities

In a series of commissions awarded by the Federal Joint Committee (G-BA) to the Institute for Quality and Efficiency in Health Care, the question is whether for certain surgical procedures, a correlation can be shown between the volume of services provided per hospital and the quality of treatment results.

28 Dec 2020

Study identifies the effects of malnutrition on patient survival after cardiac surgery

Nutrients are the structural components of food that the body needs to function properly. They are divided into macronutrients (proteins, fats, carbohydrates) and micronutrients (vitamins, provitamins, various minerals, and so on). Their shortage is called nutritional deficiency.

28 Dec 2020

Higher BMI linked to increased risk of SARS-CoV-2 infection

Researchers at the University of Miami Miller School of Medicine, USA, revealed that the spike-specific immunoglobulin G antibodies in obese people are negatively associated with body mass index (BMI) and serum levels of proinflammatory and metabolic markers of pulmonary inflammation.

24 Dec 2020

Study shows how human brains navigate physical space and keep track of others' location

For the first time, scientists have recorded how our brains navigate physical space and keep track of others' location. Researchers used a special backpack to wirelessly monitor the brain waves of epilepsy patients as each one walked around an empty room hunting for a hidden, two-foot spot.

24 Dec 2020

Study reveals the role of SETD2 protein in cancer cells, cell migration, and autophagy

SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell.

24 Dec 2020

Study examines sex differences in the cause of death after stroke

Women were 39% more likely to die by 1 year after a first stroke. The sex difference was due to advanced age and more severe strokes in women, according to a new study in the Journal of Women's Health.

23 Dec 2020

Heart News and Research

Research offers clues on why pregnancy may raise risk of organ transplant rejection

USF researchers discover promising new compound to open constricted airways

Machine-learning method can crunch data to find new uses for existing drugs

New analysis finds no benefit in providing supplemental oxygen to mothers during childbirth

People with detectable brown fat less likely to suffer cardiac and metabolic conditions

Smoking traditional cigarettes along with e-cigarettes causes harmful health effects

Higher hemoglobin threshold does not improve outcomes in preterm infants

New cell therapy can boost immunotherapy against breast cancer

Scientists discover cell responsible for triggering chronic, low-level inflammation in fat tissue

FDA-approved COVID-19 drug should be used cautiously, says UC researcher

Brain damage is not caused by direct COVID-19 attack, indicates study

New UCLA-developed device transfers mitochondria into 100,000 or more recipient cells

Stopping RAS inhibitors linked to risk of adverse outcomes in patients with chronic kidney disease

FDA approves first generic glucagon for injection to treat severe hypoglycemia

Heart transplantations: Larger case volumes correlate with higher survival probabilities

Study identifies the effects of malnutrition on patient survival after cardiac surgery

Higher BMI linked to increased risk of SARS-CoV-2 infection

Study shows how human brains navigate physical space and keep track of others' location

Study reveals the role of SETD2 protein in cancer cells, cell migration, and autophagy

Study examines sex differences in the cause of death after stroke

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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