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International coalition develops classification criteria for 25 subtypes of uveitis

An international coalition of eye researchers used machine learning to develop classification criteria for 25 of the most common types of uveitis, a collection of over 30 diseases characterized by inflammation inside the eye.

7 Jun 2021

Potential leptin therapy for nonalcoholic steatohepatitis

In those with fatty liver disease, a person's fat goes to their liver instead of their fat tissue, either because of an absence of fat depots, which is seen in the rare genetic disease lipodystrophy, or because the depots are too full, which is seen in people with obesity.

7 Jun 2021

New report highlights enormous disease burden and treatment gap of osteoporosis in Europe

New International Osteoporosis Foundation report provides unique overview of osteoporosis in Europe, revealing the enormous disease burden and an unacceptable treatment gap; 71% of women at high risk of fracture are not receiving much-needed medication.

7 Jun 2021

Gene therapy may be a safe and effective single-dose treatment for soft bone disease

A preclinical study led by scientists at Sanford Burnham Prebys has established that AAV8-TNAP-D10--a gene therapy that replaces a key enzyme found in bone--may be a safe and effective single-dose treatment for hypophosphatasia (HPP).

7 Jun 2021

FDA grants accelerated approval for first-of-its-kind Alzheimer's treatment

Today, the U.S. Food and Drug Administration approved Aduhelm (aducanumab) for the treatment of Alzheimer's, a debilitating disease affecting 6.2 million Americans. Aduhelm was approved using the accelerated approval pathway, which can be used for a drug for a serious or life-threatening illness that provides a meaningful therapeutic advantage over existing treatments.

7 Jun 2021

Covid was a tipping point for telehealth. If some have their way, Virtual visits are here to stay.

As the covid crisis wanes and life approaches normal across the U.S., health industry leaders and many patient advocates are pushing Congress and the Biden administration to preserve the pandemic-fueled expansion of telehealth that has transformed how millions of Americans see the doctor.

7 Jun 2021

MRI-guided focused ultrasound advances brain and cancer research

By 2034, nearly one-quarter of Americans will have reached retirement age, according to the United States Census Bureau. But as people age, the brain becomes more susceptible to developing disorders, such as essential tremor, Parkinson's disease, and tumors.

7 Jun 2021

Patients hospitalized with active cancer are more likely to die from COVID-19

New research indicates that patients hospitalized with active cancer were more likely to die from COVID-19 than those with a history of cancer or those without any cancer diagnosis.

7 Jun 2021

Researchers create cellular and spatial “atlas” of the choroid plexus during different life stages

Once viewed merely as a producer of the cerebrospinal fluid (CSF) bathing the brain and spinal cord, the choroid plexus is now known to be a key player in brain development and immunity.

7 Jun 2021

New drug reduces tumor size in lung cancer patients who have a specific, disease-causing change

A new drug reduced tumor size in patients who have lung cancer with a specific, disease-causing change in the gene KRAS, a study found.

7 Jun 2021

Sophisticated brain models can predict language recovery in Hispanic stroke survivors

At Boston University, a team of researchers is working to better understand how language and speech is processed in the brain, and how to best rehabilitate people who have lost their ability to communicate due to brain damage caused by a stroke, trauma, or another type of brain injury.

7 Jun 2021

New treatment option offers disease control and extends life in patients with advanced prostate cancer

Cancer researchers say they have established a new, life-extending treatment option for men with prostate cancer that has spread and become resistant to hormone therapy.

5 Jun 2021

New treatment may improve outcomes for patients with BRCA mutation-associated early breast cancer

Results were released this week on a new treatment with the potential to improve the outcomes for patients with hereditary BRCA mutations and high-risk, early-stage breast cancer.

5 Jun 2021

SARS-CoV-2 evades neutralizing antibodies and rapidly spreads by cell fusion, finds study

In a new study by researchers in the UK, Germany and South Africa, this process is visualized using time-lapse microscopy of a human cell lung line, demonstrating that SARS-CoV-2 can induce cell-to-cell fusion within 6 hours post-infection. Further, the application of neutralizing monoclonal antibodies or convalescent plasma was unable to prevent the spread of the virus by this mechanism, suggesting that removing SARS-CoV-2 from cells permissive of cell membrane fusion could be more difficult than other types of cell.

4 Jun 2021

FDA weighs approval of a lucrative Alzheimer’s drug but benefits are iffy

The Food and Drug Administration's decision next week whether to approve the first treatment for Alzheimer's disease highlights a deep division over the drug's benefits as well as criticism about the integrity of the FDA approval process.

4 Jun 2021

Post-COVID-19 assessment shows long-lasting consequences for many non-hospitalized individuals

Complications following COVID-19 infection require quick identification and management to help plan policy and health system responses. Researchers in the UK recently described the 12-month experience of the first dedicated post-COVID clinical service in the UK to include both hospitalized and non-hospitalized COVID-19 patients. This study has been released on the medRxiv* the preprint server.

4 Jun 2021

A lack of oversight for unproven stem cell interventions is a global public health problem

Authors are urging the WHO to establish an Exert Advisory Committee on Regenerative Medicine to provide harmony to the national regulations on the SCI industry.

4 Jun 2021

Researchers test the impact of deploying artificial intelligence for radiation cancer therapy

The impact of deploying Artificial Intelligence (AI) for radiation cancer therapy in a real-world clinical setting has been tested by Princess Margaret researchers in a unique study involving physicians and their patients.

4 Jun 2021

Study: Nasal therapy is more effective than commonly used IgG antibodies at neutralizing COVID-19 virus

A nasal therapy, built upon on the application of a new engineered IgM antibody therapy for COVID-19, was more effective than commonly used IgG antibodies at neutralizing the COVID-19 virus in animal models, according to research recently published by The University of Texas Health Science Center at Houston (UTHealth), The University of Texas Medical Branch at Galveston (UTMB Health), the University of Houston, and IGM Biosciences, Inc.

4 Jun 2021

Two repurposed drugs inhibit SARS-CoV-2 entry factors in a synergistic manner

A preprint paper uploaded to the bioRxiv* server shows how combining drugs targeting different entry factors of the host cell may prevent infection by the virus.

3 Jun 2021

Therapy News and Research

International coalition develops classification criteria for 25 subtypes of uveitis

Potential leptin therapy for nonalcoholic steatohepatitis

New report highlights enormous disease burden and treatment gap of osteoporosis in Europe

Gene therapy may be a safe and effective single-dose treatment for soft bone disease

FDA grants accelerated approval for first-of-its-kind Alzheimer's treatment

Covid was a tipping point for telehealth. If some have their way, Virtual visits are here to stay.

MRI-guided focused ultrasound advances brain and cancer research

Patients hospitalized with active cancer are more likely to die from COVID-19

Researchers create cellular and spatial “atlas” of the choroid plexus during different life stages

New drug reduces tumor size in lung cancer patients who have a specific, disease-causing change

Sophisticated brain models can predict language recovery in Hispanic stroke survivors

New treatment option offers disease control and extends life in patients with advanced prostate cancer

New treatment may improve outcomes for patients with BRCA mutation-associated early breast cancer

SARS-CoV-2 evades neutralizing antibodies and rapidly spreads by cell fusion, finds study

FDA weighs approval of a lucrative Alzheimer’s drug but benefits are iffy

Post-COVID-19 assessment shows long-lasting consequences for many non-hospitalized individuals

A lack of oversight for unproven stem cell interventions is a global public health problem

Researchers test the impact of deploying artificial intelligence for radiation cancer therapy

Study: Nasal therapy is more effective than commonly used IgG antibodies at neutralizing COVID-19 virus

Two repurposed drugs inhibit SARS-CoV-2 entry factors in a synergistic manner

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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