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Study shows cellular differences in brain development between modern humans and Neanderthals

Dresden and Leipzig researchers find that stem cells in the developing brain of modern humans take longer to divide and make fewer errors when distributing their chromosomes to their daughter cells, compared to those of Neanderthals.

29 Jul 2022

Innovative microscopy method reveals how neurons struggle to reach their destination in Rett syndrome models

Using an innovative microscopy method, scientists at The Picower Institute for Learning and Memory at MIT observed how newborn neurons struggle to reach their proper places in advanced human brain tissue models of Rett syndrome, producing new insight into how developmental deficits observed in the brains of patients with the devastating disorder may emerge.

29 Jul 2022

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

Wake Forest Institute for Regenerative Medicine researchers are using a tumor organoid system to examine the effects of metabolites secreted by bacteria on a specialized immunotherapy – immune checkpoint blockage, a promising cancer treatment development – to determine why some patients don't respond or develop a resistance to the treatment over time.

29 Jul 2022

Researchers investigate the protection against meningococcal infection in hematopoietic stem cell transplant recipients

The team in the Hematology Department at Henri Mondor AP-HP Hospital, coordinated by Dr. Christine Robin, and scientists from the Institut Pasteur (the Invasive Bacterial Infections Unit led by Professor Muhamed-Kheir Taha) recently studied protection against meningococcal infection in patients who had received hematopoietic stem cell transplantation.

29 Jul 2022

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

Study examines the feasibility of patient engagement with digital life coaching during stem cell transplant

JMIR Publications recently published "Digital Life Coaching During Stem Cell Transplantation: Development and Usability Study" in JMIR Formative Research which reported that the authors launched a single-arm pilot study to investigate the feasibility of patient engagement with digital life coaching (DLC) during this intensive period.

29 Jul 2022

Study finds asymptomatic SARS-CoV-2 infection induced comparable memory B cell responses to mild symptomatic infection in young adults

Researchers identified that among healthy young adults, the development of SARS-CoV-2 triggered memory B cell and antibody reactions were equivalent following mildly symptomatic or asymptomatic infections.

29 Jul 2022

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

With this approval, RINVOQ® is the first and only Janus Kinase inhibitor approved to treat patients across the spectrum of axial spondyloarthritis (nr-axSpA and ankylosing spondylitis) in the EU.

From AbbVie 29 Jul 2022

AI image analysis tool enables insight creation without AI expertise

Leica Microsystems, a leader in microscopy and scientific instrumentation, has released a new version of its AI-powered image analysis solution, Aivia.

From Leica Microsystems GmbH 29 Jul 2022

Tannins as therapeutic agents against SARS-CoV-2

Researchers reviewed tannins as therapeutic agents against SARS-CoV-2.

29 Jul 2022

Proteomics profiling of COVID-19 patients identifies dysregulated proteins and pathways

Researchers assessed the impact of SARS-CoV-2 infection and severity on coronary and Alzheimer’s disease pathways.

29 Jul 2022

Modifi Bio comes up with a new technology to combat cancer cells with DNA modification

Modifi Biosciences announced today that the journal Science has published a critical study validating the company's novel oncology platform based on new classes of molecules that exploit tumor-associated DNA repair defects through direct cancer cell DNA modification.

29 Jul 2022

New glioma drug may represent a paradigm for designing therapeutics exploiting specific DNA repair

A new class of glioma drugs exploits tumors that lack the DNA repair enzyme MGMT; the drugs lead to the generation of cytotoxic DNA and selectively kill tumor cells without the risk of resistance, researchers report.

29 Jul 2022

Study uncovers the crucial roles of kinesins during the malaria parasite life cycle

Scientists at the University of Nottingham have made a major breakthrough in understanding how malaria parasites divide and transmit the disease, which could be a major step forwards in helping to prevent one of the biggest killer infections in the world.

29 Jul 2022

New breakthrough shows antimicrobial resistance is more evolved than previously recognized

Researchers have discovered a significant and previously unknown mechanism that many bacteria use to resist antibiotics.

29 Jul 2022

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Of the roughly 20,000 people in the U.S. diagnosed with esophageal cancer this year, just 4,000 are likely to still be alive in 2027.

28 Jul 2022

Study highlights impaired ketogenesis as a potential confounder of severe COVID-19

In severe Covid-19 patients, the metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order to fight the virus effectively.

28 Jul 2022

New method for organoid production could help advance research studies

As the idea of growing tiny human organs in lab dishes has moved in recent years from futuristic science fiction to actual bioscientific reality, the usefulness of organoids as a research tool for studying the digestive system swiftly encountered a bottleneck - these valuable tissues are quite difficult to make.

28 Jul 2022

New bacteria-killing copper coating could reduce infections from high-touch surfaces

A new copper coating that kills bacteria quicker and in greater amounts than current formulations could soon be available for hospitals and other high-traffic facilities.

28 Jul 2022

The bat-virus relationship examined

A new study examines the role of bats as reservoirs of several viruses and the factors that contribute to the emergence of these viruses.

28 Jul 2022

B Cell News and Research

Study shows cellular differences in brain development between modern humans and Neanderthals

Innovative microscopy method reveals how neurons struggle to reach their destination in Rett syndrome models

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

Researchers investigate the protection against meningococcal infection in hematopoietic stem cell transplant recipients

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Study examines the feasibility of patient engagement with digital life coaching during stem cell transplant

Study finds asymptomatic SARS-CoV-2 infection induced comparable memory B cell responses to mild symptomatic infection in young adults

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

AI image analysis tool enables insight creation without AI expertise

Tannins as therapeutic agents against SARS-CoV-2

Proteomics profiling of COVID-19 patients identifies dysregulated proteins and pathways

Modifi Bio comes up with a new technology to combat cancer cells with DNA modification

New glioma drug may represent a paradigm for designing therapeutics exploiting specific DNA repair

Study uncovers the crucial roles of kinesins during the malaria parasite life cycle

New breakthrough shows antimicrobial resistance is more evolved than previously recognized

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Study highlights impaired ketogenesis as a potential confounder of severe COVID-19

New method for organoid production could help advance research studies

New bacteria-killing copper coating could reduce infections from high-touch surfaces

The bat-virus relationship examined

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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