Genes News and Research

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Two major forms of CD44 have distinct biological functions in breast cancer, shows study

One of the main obstacles to successfully treating breast cancer is the cells' ability to change in ways that make them resistant to treatment.

29 Jan 2019

Big data opens door for characterizing immunity-related genome in Japanese population

Although different genes are distributed widely across chromosomes, many genes related to the immune system are clustered together on human chromosome 6, in a segment called the major histocompatibility complex (MHC) region.

29 Jan 2019

Fibrosis-targeting drugs may benefit patients with late-stage, metastatic breast cancer

A Massachusetts General Hospital (MGH) research team has found that the overgrowth of connective called fibrosis may block the effectiveness of immunotherapies against metastatic breast cancer.

29 Jan 2019

RNA-induced gene fusion can occur in mammalian cells, reveals study

A fusion gene is a new gene made by joining parts of two different genes. The current thought is that fusion genes can happen in cells with unstable genome when part of the DNA from one chromosome moves to another chromosome.

29 Jan 2019

Research provides new understanding of genome regulation in early life

After the fertilization of an egg cell, two become one; two sets of genetic information combine to form a genome. We can think of the egg and sperm as information capsules with stored instructions for starting a new life, but post fertilization, what kick starts the interpretation of these instructions?

29 Jan 2019

EZH2 mutations can be used as marker for diagnosing different types of cancers

Inside the cell, DNA is tightly wrapped around proteins and packed in a complex, 3D structure that we call "chromatin".

29 Jan 2019

NIH grants awarded to Nanoscope to recruit talent and develop optogenetic delivery platforms

Retinal dystrophies such as Age-related macular degeneration (AMD) are a major cause of vision loss in aging populations. National Eye Institute (NEI) estimates that the prevalence of advanced AMD will grow to nearly 3 million by 2020.

29 Jan 2019

Antibiotic-resistant superbugs have reached the Arctic

An international team of researchers has identified antibiotic-resistant genes (ARGs) in an area of the arctic that have spread from urban India.

28 Jan 2019

Stress and paradoxical sleep associated with pathways of brain cell death and survival

The first and most distinct consequence of daily mild stress is an increase in rapid-eye-movement (REM) sleep, a new study in the journal PNAS reports. The research also demonstrated that this increase is associated with genes involved in cell death and survival.

28 Jan 2019

Study identifies new genetic variant associated with ARDS

An international study in which Javier Belda, Professor of Surgery at the University of Valencia and Incliva researcher, participated, has identified a new genetic variant associated with Acute Respiratory Distress Syndrome.

28 Jan 2019

Gluten-free wheat can be produced for people with celiac disease by using gene editing

One to two per cent of the population has Celiac Disease (CD), an immune reaction to gluten. Wheat grains contain gluten, a mixture of glutenin and gliadin proteins, which build a network that gives wheat bread its unique properties and quality.

28 Jan 2019

'Antibiotic-Resistant Genes' found in one of the last pristine places on earth

Antibiotic-Resistant Genes that were first detected in urban India have been found 8,000 miles away in one of the last 'pristine' places on earth, a new study has shown.

28 Jan 2019

Researchers create synthetic growth factor that offers comparable biological response

Growth factors are ligands that play important roles in the body - they are responsible for tissue regeneration, wound healing, and the maintenance and growth of cells.

28 Jan 2019

Scientists pinpoint mechanism that leads to steroid diabetes

Patients undergoing long-term treatment with steroids may suffer from metabolic side effects. Researchers at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich, partners in the German Center for Diabetes Research, have now pinpointed a mechanism that leads to so-called steroid diabetes

25 Jan 2019

Discovery could guide future treatments for patients with hypertension

A team of Vanderbilt University Medical Center researchers, working with the U.S. Department of Veteran's Affairs, has discovered genetic associations with blood pressure that could guide future treatments for patients with hypertension.

25 Jan 2019

Evolutionary models could reveal what it takes to be a giant shark

In a paper published by Evolution, research led by Swansea University's Dr Catalina Pimiento and co-authored by an international team of scientists from the UK, Europe and the USA examined the biological traits of all sharks and rays before running a series of evolutionary models to seek how gigantism evolved over time.

25 Jan 2019

Novel therapeutic approach for treatment of leukemia

The BCR/ABL gene, which does not occur among healthy people, has been shown to be a causative agent in the pathogenesis of B-cell acute lymphocytic leukemia.

24 Jan 2019

Study uncovers new link between inflammation and cancer

Severe inflammation in tissues is often associated with the occurrence of cancer. The mechanism linking both these conditions is not clearly understood. Furthermore, inflamed and cancerous tissues contain a heterogenous mix of damaged and protective cells.

24 Jan 2019

Newly developed algorithms can predict and correct errors in single cell analyses

Modern technology makes it possible to sequence individual cells and to identify which genes are currently being expressed in each cell.

24 Jan 2019

Researchers reveal important signaling pathway in breast cancer

Researchers at Kanazawa University report in Proceedings of the National Academy of Sciences of the United States of America that a particular signaling pathway in breast-cancer tumors causes cancer cells to divide symmetrically, expanding the tumor. Inhibiting the pathway by drugs could become a strategy for eliminating the cancer cells.

24 Jan 2019

Genes News and Research

Two major forms of CD44 have distinct biological functions in breast cancer, shows study

Big data opens door for characterizing immunity-related genome in Japanese population

Fibrosis-targeting drugs may benefit patients with late-stage, metastatic breast cancer

RNA-induced gene fusion can occur in mammalian cells, reveals study

Research provides new understanding of genome regulation in early life

EZH2 mutations can be used as marker for diagnosing different types of cancers

NIH grants awarded to Nanoscope to recruit talent and develop optogenetic delivery platforms

Antibiotic-resistant superbugs have reached the Arctic

Stress and paradoxical sleep associated with pathways of brain cell death and survival

Study identifies new genetic variant associated with ARDS

Gluten-free wheat can be produced for people with celiac disease by using gene editing

'Antibiotic-Resistant Genes' found in one of the last pristine places on earth

Researchers create synthetic growth factor that offers comparable biological response

Scientists pinpoint mechanism that leads to steroid diabetes

Discovery could guide future treatments for patients with hypertension

Evolutionary models could reveal what it takes to be a giant shark

Novel therapeutic approach for treatment of leukemia

Study uncovers new link between inflammation and cancer

Newly developed algorithms can predict and correct errors in single cell analyses

Researchers reveal important signaling pathway in breast cancer

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