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Determining the dynein-dynactin complex structure: an interview with Dr Gabriel C. Lander

This is a macromolecular assembly is made up of two components, dynein and dynactin, that works to move molecular cargo (organelles, RNA, vesicles, proteins, viruses) along microtubule highways within our cells.

16 Aug 2015

New study examines how race and gender relate to Medicare Part D's coverage gap

Medicare Part D provides help to beneficiaries struggling with the cost of prescriptions drugs, but the plan's coverage gap hits some populations harder than others, particularly African-Americans age 65 and older. Reaching, or even approaching, the gap affects access to medication and influences whether those medications are taken as prescribed.

15 Aug 2015

Medicare patients in rural settings have lower rates of post-discharge follow-up care

Medicare patients in rural areas have lower rates of follow-up care after leaving the hospital--which may place them at higher risk of emergency department (ED) visits and repeat hospitalizations, according to a study in the September issue of Medical Care.

15 Aug 2015

PTSD not associated with increased risk for cancer, find BUSM researchers

In the largest study to date that examines Post Traumatic Stress Disorder (PTSD) as a risk factor for cancer, researchers from Boston University School of Medicine, have shown no evidence of an association.

15 Aug 2015

New study explores impact of climate change on human health

Researchers at Columbia University's National Center for Disaster Preparedness and the University of Washington have published a new study focused on the public health implications of climate change. The article explores climate change impacts on human health in the U.S. Gulf Coast and has implications for this and other coastal regions that are particularly vulnerable to climate change.

14 Aug 2015

UT Arlington, UNTHSC researchers develop user-friendly system alerts for people with sleep apnea

Masks worn by those with sleep apnea can leak at night and be so uncomfortable that they often drive users away from treatment. But a new system being developed by researchers at UNT Health Science Center and The University of Texas at Arlington could make it easier for the estimated 18 million people with sleep apnea to get a good night's rest.

14 Aug 2015

Women's Medicine Collaborative awarded NIH grant to study link between placenta and sleep abnormalities

The National Institutes of Health has awarded $2.7 million to the Women's Medicine Collaborative to study the placenta and its function to determine whether changes in the placenta are linked to sleep abnormalities.

14 Aug 2015

PTC Therapeutics closes $150 million of convertible senior notes

PTC Therapeutics, Inc. announced today the closing of its previously announced private offering of $150 million in aggregate principal amount of its convertible senior notes due 2022 (the "Notes"), including the full exercise by the initial purchasers of an option to purchase an additional $25 million in aggregate principal amount of the Notes.

14 Aug 2015

Algorithm encompassing clinical and genetic factors predicts PD

Researchers have devised a model that distinguishes patients with Parkinson’s disease from those without the condition without relying on motor features.

14 Aug 2015

CML survey reveals patient TKI adherence, disease anxiety

Survey results suggest that chronic myeloid leukaemia patients using tyrosine kinase inhibitor therapy have good adherence to treatment but might benefit from counselling regarding their illness.

14 Aug 2015

Risk for endophthalmitis no higher with Avastin, finds study

Eye injections of the drug Avastin, used to treat retinal diseases, bring no greater risk of endophthalmitis, a potentially blinding eye infection, than injections with the much more expensive drug Lucentis made by the same company, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Their findings are published today in JAMA Ophthalmology.

14 Aug 2015

New system accurately and reliably captures patient experience with cancer drug side effects

In cancer clinical trials, symptom side effects patients experience, like nausea, are typically reported by doctors, and not directly by patients. Previous research has shown that doctors under-report these symptoms.

14 Aug 2015

‘Medical foods’ for patients with rare IEMs may cause harm when not carefully managed

Many "medical foods" are designed to help manage patients with rare inborn errors of metabolism (IEMs), and can help prevent serious and life-threatening complications. However, such special foods may cause harm in some patients when their use is not carefully monitored and managed, according to a research team led by scientists at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health.

14 Aug 2015

Two new studies on eosinophilic granulomatosis with polyangiitis selected by Vasculitis Foundation

The Vasculitis Foundation is pleased to announce it has selected two new research studies on eosinophilic granulomatosis with polyangiitis (EGPA) /Churg Strauss for funding in the amount of $98,000.

14 Aug 2015

Prion protein could play a role in depression

The discovery of antidepressant drugs in the 1950s led to the first biochemical hypothesis of depression, known as the monoamine hypothesis. This hypothesis proposes that an imbalance of certain brain chemicals is the key cause of depression.

14 Aug 2015

Neuroscientist discovers how animal's biological clock wakes up, goes to sleep

Fifteen years ago, an odd mutant fruit fly caught the attention and curiosity of Dr. Ravi Allada, a circadian rhythms expert at Northwestern University, leading the neuroscientist to recently discover how an animal's biological clock wakes it up in the morning and puts it to sleep at night.

14 Aug 2015

CASI reports financial results for second quarter 2015

CASI Pharmaceuticals, Inc., a biopharmaceutical company dedicated to the acquisition, development and commercialization of innovative therapeutics addressing cancer and other unmet medical needs for the global market with a commercial focus on China, today reported financial results for the three and six months ended June 30, 2015.

14 Aug 2015

NSF awards EAGER grant to expand use of temperature-activated protein switches in neurons

Troy Zars, Mirela Milescu, and Lorin Milescu, faculty members of the Division of Biological Sciences and the Interdisciplinary Neuroscience Program at the University of Missouri, have been awarded an Early Concept Grant for Exploratory Research (EAGER) from the National Science Foundation to expand the use of a temperature-activated protein switches in neurons. The new technology could lead to a better understanding of brain disorders in humans.

14 Aug 2015

Anti-smoking laws lead to decrease in stillbirths

Stillbirths have dropped by almost eight per cent in England since the smoking ban was introduced, research shows.

14 Aug 2015

MGH papers reveal the way anesthetics affect brains of older patients and children

Recent Massachusetts General Hospital (MGH) investigations into the neurobiology underlying the effects of general anesthesia have begun to reveal the ways different anesthetic agents alter specific aspects of the brain's electrical signals, reflected by EEG (electroencephalogram) signatures. While those studies have provided information that may lead to improved techniques for monitoring the consciousness of patients receiving general anesthesia, until now they have been conducted in relatively young adult patients.

14 Aug 2015

Research News and Research

Determining the dynein-dynactin complex structure: an interview with Dr Gabriel C. Lander

New study examines how race and gender relate to Medicare Part D's coverage gap

Medicare patients in rural settings have lower rates of post-discharge follow-up care

PTSD not associated with increased risk for cancer, find BUSM researchers

New study explores impact of climate change on human health

UT Arlington, UNTHSC researchers develop user-friendly system alerts for people with sleep apnea

Women's Medicine Collaborative awarded NIH grant to study link between placenta and sleep abnormalities

PTC Therapeutics closes $150 million of convertible senior notes

Algorithm encompassing clinical and genetic factors predicts PD

CML survey reveals patient TKI adherence, disease anxiety

Risk for endophthalmitis no higher with Avastin, finds study

New system accurately and reliably captures patient experience with cancer drug side effects

‘Medical foods’ for patients with rare IEMs may cause harm when not carefully managed

Two new studies on eosinophilic granulomatosis with polyangiitis selected by Vasculitis Foundation

Prion protein could play a role in depression

Neuroscientist discovers how animal's biological clock wakes up, goes to sleep

CASI reports financial results for second quarter 2015

NSF awards EAGER grant to expand use of temperature-activated protein switches in neurons

Anti-smoking laws lead to decrease in stillbirths

MGH papers reveal the way anesthetics affect brains of older patients and children

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