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FDA approves PROLENSA for treatment of inflammation, pain after cataract surgery

Bausch + Lomb, the global eye health company, today announced that the U.S. Food and Drug Administration has approved the company's New Drug Application for PROLENSA (bromfenac ophthalmic solution) 0.07 percent prescription eye drop, an innovative once-daily nonsteroidal anti-inflammatory drug for the treatment of postoperative inflammation and reduction of ocular pain in patients who have undergone cataract surgery.

9 Apr 2013

ISP of Chile approves Trigemina's protocol for Phase 2 clinical study of TI-001

Trigemina, Inc., a biopharmaceutical company focused on the discovery and development of non-narcotic, nasally delivered, analgesic drug products, today announced that the Instituto de Salud Publica of Chile has approved the Company's protocol for its Phase 2 clinical study of TI-001, intranasal oxytocin, for the treatment of chronic migraine.

9 Apr 2013

Researchers discover that fruit fly mutation holds clues for treating motor neuron diseases

A team of researchers, led by Marc Freeman, PhD, an early career scientist with the Howard Hughes Medical Institute and associate professor of neurobiology at the University of Massachusetts Medical School have discovered a gene in the fruit fly Drosophila melanogaster that, when mutant, blocks the self-destruction of damaged axons, which could hold clues to treating motor neuron diseases, such as amyotrophic lateral sclerosis.

9 Apr 2013

Using MRI to measure blood flow over atherosclerotic plaques can help identify high-risk plaques

Researchers from Boston University School of Medicine (BUSM) have shown that using magnetic resonance imaging (MRI) to measure blood flow over atherosclerotic plaques could help identify plaques at risk for thrombosis.

7 Apr 2013

AIM suppression could help prevent obesity-associated diseases

Obesity is linked to the widespread epidemics of diabetes and heart disease that plague society, but a lesser-known fact is that the weight can also lead to autoimmune disease.

5 Apr 2013

UC San Francisco researchers outline cell-based therapeutics as a "third pillar” of medicine

Treating patients with cells may one day become as common as it is now to treat the sick with drugs made from engineered proteins, antibodies or smaller chemicals, according to UC San Francisco researchers.

4 Apr 2013

Overexpression of miR-155 promotes growth of blood vessels in tumors and metastasis

Researchers at Moffitt Cancer Center have determined that the overexpression of microRNA-155 (miR-155), a short, single strand of ribonucleic acid encoded by the miR-155 host gene, promotes the growth of blood vessels in tumors, tumor inflammation, and metastasis.

4 Apr 2013

Weight loss and heart damage: an interview with Dr Lili Barouch, Johns Hopkins University School of Medicine

Obesity causes an increase in the stiffness of the heart, making it hard for the heart muscle to relax and fill with blood in between heartbeats. This abnormal stiffness can lead to congestive heart failure and other problems as it becomes more severe.

4 Apr 2013

Integrated advanced cardiovascular imaging modalities can change cardiac care

Focusing on problem solving clinical approach, places the emphasis firmly on identifying the best test to answer each specific question in the most efficient way.

4 Apr 2013

Schizophrenia patients experiencing relapse are more likely to develop UTIs

Schizophrenia patients experiencing relapse are 29 times more likely than healthy individuals to have a urinary tract infection, researchers report.

4 Apr 2013

Same factor that helps fight off severe inflammatory ailments also functions as enemy

The same factor in our immune system that is instrumental in enabling us to fight off severe and dangerous inflammatory ailments is also a player in doing the opposite at a later stage, causing the suppression of our immune response.

4 Apr 2013

UCLA Children's Discovery and Innovation Institute to drive research on children's health

For more than 60 years, the faculty and staff at Mattel Children's Hospital UCLA and the department of pediatrics at the David Geffen School of Medicine at UCLA have conducted pioneering research, delivered state-of-the-art patient care and expertly trained future pediatricians.

4 Apr 2013

Study suggests drugs prescribed to lower cholesterol may be effective against macular degeneration

A new study raises the intriguing possibility that drugs prescribed to lower cholesterol may be effective against macular degeneration, a blinding eye disease. Researchers at Washington University School of Medicine in St. Louis have found that age-related macular degeneration, the leading cause of vision loss in Americans over 50, shares a common link with atherosclerosis.

3 Apr 2013

Ulcerative colitis and Crohn’s disease treatments: an interview with Dr Parikh, vice president, general medicine, Takeda

Ulcerative colitis (UC) and Crohn’s disease (CD) are both relapsing and remitting chronic diseases of bowel inflammation. By that I mean they flare and physicians try to get the flare under control and try to induce remission. However, despite a number of treatments available, they tend to relapse.

From Takeda 3 Apr 2013

Isis Pharmaceuticals starts ISIS-APOARx Phase 1 clinical study for treatment of atherosclerosis

Isis Pharmaceuticals, Inc. announced today that it has initiated a Phase 1 clinical study for ISIS-APOARx, an antisense drug targeting apolipoprotein(a) for the treatment of atherosclerosis.

3 Apr 2013

Imbalance between neutrophil elastase and α1-antitrypsin leads to obesity, inflammation

Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute have discovered that an imbalance between an enzyme called neutrophil elastase and its inhibitor causes inflammation, obesity, insulin resistance, and fatty liver disease.

3 Apr 2013

Researchers find association between melatonin, type 2 diabetes

With previous evidence suggesting that melatonin may have a role in glucose metabolism, researchers have found an independent association between decreased secretion of melatonin and an increased risk for the development of type 2 diabetes, according to a study in the April 3 issue of JAMA.

3 Apr 2013

Scientists say DHA-rich fish oil enhances B cell activity

Fish oil rich in DHA and EPA is widely believed to help prevent disease by reducing inflammation, but until now, scientists were not entirely sure about its immune enhancing effects. A new report appearing in the April 2013 issue of the Journal of Leukocyte Biology, helps provide clarity on this by showing that DHA-rich fish oil enhances B cell activity, a white blood cell, challenging the notion that fish oil is only immunosuppressive.

2 Apr 2013

Minocycline can help reduce hemorrhagic stroke damage

A new study will help determine if an antibiotic is a partial antidote for the poisonous effect blood has on the brain following a hemorrhagic stroke, researchers say.

2 Apr 2013

Study: Pradaxa drug may increase risk and severity of viral infections

A study led by researchers at the University of North Carolina indicates that a newly approved blood thinner that blocks a key component of the human blood clotting system may increase the risk and severity of certain viral infections, including flu and myocarditis, a viral infection of the heart and a significant cause of sudden death in children and young adults.

2 Apr 2013

Inflammation News and Research

FDA approves PROLENSA for treatment of inflammation, pain after cataract surgery

ISP of Chile approves Trigemina's protocol for Phase 2 clinical study of TI-001

Researchers discover that fruit fly mutation holds clues for treating motor neuron diseases

Using MRI to measure blood flow over atherosclerotic plaques can help identify high-risk plaques

AIM suppression could help prevent obesity-associated diseases

UC San Francisco researchers outline cell-based therapeutics as a "third pillar” of medicine

Overexpression of miR-155 promotes growth of blood vessels in tumors and metastasis

Weight loss and heart damage: an interview with Dr Lili Barouch, Johns Hopkins University School of Medicine

Integrated advanced cardiovascular imaging modalities can change cardiac care

Schizophrenia patients experiencing relapse are more likely to develop UTIs

Same factor that helps fight off severe inflammatory ailments also functions as enemy

UCLA Children's Discovery and Innovation Institute to drive research on children's health

Study suggests drugs prescribed to lower cholesterol may be effective against macular degeneration

Ulcerative colitis and Crohn’s disease treatments: an interview with Dr Parikh, vice president, general medicine, Takeda

Isis Pharmaceuticals starts ISIS-APOARx Phase 1 clinical study for treatment of atherosclerosis

Imbalance between neutrophil elastase and α1-antitrypsin leads to obesity, inflammation

Researchers find association between melatonin, type 2 diabetes

Scientists say DHA-rich fish oil enhances B cell activity

Minocycline can help reduce hemorrhagic stroke damage

Study: Pradaxa drug may increase risk and severity of viral infections

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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