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SLU scientists provide promising approach in designing new drugs for DMD

In a paper published in the Nature journal Scientific Reports, Saint Louis University researchers report that a new drug reduces fibrosis (scarring) and prevents loss of muscle function in an animal model of Duchenne muscular dystrophy (DMD), providing a promising approach in designing new medications for those suffering from DMD.

8 Dec 2017

University of Adelaide receives $23.2 million for preterm birth research

The University of Adelaide has been awarded $23.2 million for new research tackling some of the world's most significant health problems, including one of the biggest killers of children: preterm birth.

8 Dec 2017

Childhood asthma linked to high maternal sugar intake during pregnancy

New research published today in the Annals of the American Thoracic Society reports that children born to mothers who drank a lot of sugary drinks during pregnancy may be at an increased risk of developing asthma during childhood.

8 Dec 2017

Prenatal and early-life consumption of sugary drinks may increase risk of mid-childhood asthma

Children between the ages of 7 and 9 may be at greater risk for developing asthma if they consumed high amounts of fructose in early childhood or their mothers drank a lot of sugar-sweetened beverages while pregnant, according to new research published online in the Annals of the American Thoracic Society.

8 Dec 2017

Parental lifespan genes could pave way for new therapeutic targets to prolong life

A large-scale international study led by the University of Exeter Medical School has discovered new genes linked to parents' lifespan - which could one day be targeted to help prolong human life.

8 Dec 2017

Stress in early life may raise risk of heart disease in adulthood

Stress in early life may change the immune response in the kidneys, increasing the risk of heart disease later in life, according to a new study. The paper, published ahead of print in the American Journal of Physiology- Renal Physiology, was chosen as an APSselect article for December.

7 Dec 2017

Large-scale study expands number of genetic markers linked to exceptional longevity

A new large-scale international study expands the number of genetic markers now known to be associated with exceptional longevity.

7 Dec 2017

Study reveals connection between restless sleep and Parkinson's disease

A study published in the neurological journal, The Lancet Neurology, has identified that patients with rapid eye movement sleep behavior disorder (RBD) have a dopamine deficiency in the brain and suffer from a form of brain inflammation. They are subjected to increased risks of developing dementia or Parkinson's disease as they grow older.

7 Dec 2017

UMSOM researchers find two-way link between TBI and intestinal changes

University of Maryland School of Medicine researchers have found a two-way link between traumatic brain injury (TBI) and intestinal changes. These interactions may contribute to increased infections in these patients, and may also worsen chronic brain damage.

7 Dec 2017

Scientists develop reversible superglue seal to treat ocular injuries

When a soldier sustains a traumatic eye injury on the battlefield, any delay in treatment may lead to permanent vision loss. With medical facilities potentially far away and no existing tools to prevent deterioration, medics are in a high-stakes race against the clock.

6 Dec 2017

Unique liver function of South American amphibian could pave way for finding a cure to cirrhosis

The unique liver function of a South American amphibian, Siphonops annulatus, could pave the way to finding a cure to the devastating liver condition cirrhosis, a new study published in the prestigious Journal of Anatomy reports.

6 Dec 2017

Specific protein negatively affects pancreatic cells and leads to cancer growth

Pancreatic cancer is one of the most aggressive forms of cancer and is currently very difficult to treat. However, the last few years have seen advances in the scientific understanding of how this cancer develops at a molecular level.

6 Dec 2017

Patients with RBD sleep disorder have risk of developing Parkinson's disease in future

Researchers from Aarhus University have discovered that patients with the RBD sleep behavior disorder lack dopamine and have a form of inflammation of the brain. This means that they are at risk of developing Parkinson's disease or dementia when they grow older.

5 Dec 2017

Conventional sunscreens do not block skin damage caused by visible light

There is something wrong with people's exposure to sunlight. Despite rising worldwide consumption of sunscreens, the number of cases of skin cancer continues to grow. One of the reasons may be the action of visible light, which is also harmful to skin and is not blocked by conventional sunscreens.

5 Dec 2017

Studies offer evidence that exercise alone can change composition of gut microbes

Two studies - one in mice and the other in human subjects - offer the first definitive evidence that exercise alone can change the composition of microbes in the gut. The studies were designed to isolate exercise-induced changes from other factors - such as diet or antibiotic use - that might alter the intestinal microbiota.

5 Dec 2017

Nearly 6% of cancers worldwide caused by diabetes and high BMI, study finds

Diabetes and high BMI (a BMI over 25 kg/m2) were the cause of 5.6% of new cancer cases worldwide in 2012 – equivalent to 792600 cases, according to the first study to quantify the proportion of cancers attributable to diabetes and high BMI published in The Lancet Diabetes & Endocrinology journal.

5 Dec 2017

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

Cancer therapies are designed to kill tumor cells, but produce tumor cell debris in the process. In a study published in The Journal of Experimental Medicine, researchers from Brigham and Women's Hospital and colleagues show that leftover debris can stimulate inflammation and tumor growth, but that molecules called resolvins can block that unwanted inflammatory response.

5 Dec 2017

FDA grants approval to first biosimilar for treatment of patients with breast, stomach cancers

The U.S. Food and Drug Administration today approved Ogivri (trastuzumab-dkst) as a biosimilar to Herceptin (trastuzumab) for the treatment of patients with breast or metastatic stomach cancer (gastric or gastroesophageal junction adenocarcinoma) whose tumors overexpress the HER2 gene (HER2+).

4 Dec 2017

Jawbone loss linked to onset of rheumatoid arthritis

Jawbone loss caused by periodontitis predates the onset of rheumatoid arthritis. This according to research from Umeå University in Sweden presented in the journal Arthritis & Rheumatology.

1 Dec 2017

Chemotherapy-generated debris from dead and dying cancer cells can stimulate tumor growth

Cancer therapies including radiation and chemotherapy seek to treat the disease by killing tumor cells. Now a team including researchers at Beth Israel Deaconess Medical Center have shown that the dead and dying cancer cells generated by chemotherapy and targeted cancer therapy paradoxically trigger inflammation that promotes aggressive tumor growth.

1 Dec 2017

Inflammation News and Research

SLU scientists provide promising approach in designing new drugs for DMD

University of Adelaide receives $23.2 million for preterm birth research

Childhood asthma linked to high maternal sugar intake during pregnancy

Prenatal and early-life consumption of sugary drinks may increase risk of mid-childhood asthma

Parental lifespan genes could pave way for new therapeutic targets to prolong life

Stress in early life may raise risk of heart disease in adulthood

Large-scale study expands number of genetic markers linked to exceptional longevity

Study reveals connection between restless sleep and Parkinson's disease

UMSOM researchers find two-way link between TBI and intestinal changes

Scientists develop reversible superglue seal to treat ocular injuries

Unique liver function of South American amphibian could pave way for finding a cure to cirrhosis

Specific protein negatively affects pancreatic cells and leads to cancer growth

Patients with RBD sleep disorder have risk of developing Parkinson's disease in future

Conventional sunscreens do not block skin damage caused by visible light

Studies offer evidence that exercise alone can change composition of gut microbes

Nearly 6% of cancers worldwide caused by diabetes and high BMI, study finds

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

FDA grants approval to first biosimilar for treatment of patients with breast, stomach cancers

Jawbone loss linked to onset of rheumatoid arthritis

Chemotherapy-generated debris from dead and dying cancer cells can stimulate tumor growth

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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