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Study shows why candidate vaccine used in HVTN 505 clinical trial not protective against HIV infection

A study by researchers at the National Institute of Allergy and Infectious Diseases and Duke University helps explain why the candidate vaccine used in the HVTN 505 clinical trial was not protective against HIV infection despite robustly inducing anti-HIV antibodies: the vaccine stimulated antibodies that recognized HIV as well as microbes commonly found in the intestinal tract, part of the body's microbiome.

31 Jul 2015

Interactive Autism Network to join National Patient-Centered Clinical Research Network

The Interactive Autism Network, a project of the Kennedy Krieger Institute supported by the Simons Foundation, was approved today for a three-year $1.6 million funding award by the Patient-Centered Outcomes Research Institute to be part of PCORnet, the National Patient-Centered Clinical Research Network.

31 Jul 2015

DNA study reveals potential treatments to delay or prevent onset of Huntington's disease

Scientists from Cardiff University believe that a treatment to prevent or delay the symptoms of Huntington’s disease could now be much closer, following a major breakthrough.

31 Jul 2015

Takeda completes post-marketing commitment and data submission for pioglitazone containing medicines

Takeda Pharmaceutical Company Limited today announced the completion of the study to fulfill the post-marketing commitment and submissions of data to regulatory authorities from the Pan European Multi-Database Bladder Cancer Risk Characterization Study, a large (n= 112,674), multi-database retrospective matched cohort study, conducted in four European countries, for pioglitazone containing medicines, including ACTOS with up to 10 years of follow-up.

31 Jul 2015

New blood test could help diagnose severity of traumatic brain injury

A new blood test could help emergency room doctors quickly diagnose traumatic brain injury and determine its severity.

31 Jul 2015

Researchers develop evidence-based model that can predict amount of nicotine released from e-cigarette

Virginia Commonwealth University Massey Cancer Center researchers at the VCU Center for the Study of Tobacco Products (CSTP) have developed the first ever, evidence-based model that can predict with up to 90 percent accuracy the amount of nicotine emitted by an electronic cigarette (e-cigarette).

31 Jul 2015

Female patients with depression have abnormally high expression levels of glutamate receptor genes

Numerous genes that regulate the activity of a neurotransmitter in the brain have been found to be abundant in brain tissue of depressed females. This could be an underlying cause of the higher incidence of suicide among women, according to research at the University of Illinois at Chicago.

31 Jul 2015

New Penn study questions relevance of fish oil-derived SPMs and their anti-inflammatory effects in humans

The importance of a diet rich in fish oils - now a billion dollar food-supplement industry -- has been debated for over half a century. A few large clinical trials have supported the idea that fish oils confer therapeutic benefits to patients with cardiovascular disease. Researchers think that hearts and blood vessels may benefit in part from their anti-inflammatory properties.

31 Jul 2015

amfAR releases recommendations to help U.S. states to achieve goals of National HIV/AIDS Strategy

Major achievements have been made in the domestic HIV/AIDS response as a result of increased realignment and coordination of efforts at the federal level. However, that level of consistent coordination and alignment has yet to take place in most states. In an effort to identify what needs to be done, amfAR, The Foundation for AIDS Research, in collaboration with the National HIV/AIDS Initiative at the O'Neill Institute for National and Global Health Law at Georgetown Law, has released a set of recommendations for how states across the U.S. can improve HIV prevention and care outcomes in an effort to achieve the goals identified within the National HIV/AIDS Strategy.

31 Jul 2015

IU scientists find evidence that invisible war between microorganisms may affect human health

Health experts have warned for years that the overuse of antibiotics is creating "superbugs" able to resist drugs treating infection.

31 Jul 2015

IUPUI researchers receive NIH grant to study effect of depression treatment on cardiovascular disease

Indiana University-Purdue University Indianapolis researchers led by Jesse Stewart of the School of Science, have received a $2.6 million grant from the National Institutes of Health to conduct the first randomized controlled trial to determine whether depression treatment can help prevent the development of cardiovascular disease.

31 Jul 2015

Pharmacist-included medical care teams help patients better control blood pressure

If you have hypertension, it pays to include a pharmacist in a medical care team. That's the upshot from research by the University of Iowa that found patients with uncontrolled hypertension had better blood pressure control when being cared for by pharmacists working in care teams (with a physician, for example) than patients who relied mostly on a doctor for medication guidance.

31 Jul 2015

GW Cancer Institute receives Eugene Washington PCORI Engagement Award to create online site for patient-centered care

The George Washington University Cancer Institute has been approved for a $250,000 Eugene Washington PCORI Engagement Award by the Patient-centered Outcomes Research Institute to create the first-ever online Community of Practice for patient-centered care.

31 Jul 2015

Prostate cancer discovery may improve treatment strategies

Scientists from Cancer Research UK have discovered that there are five different types of prostate cancer and have found a way of distinguishing between them. These findings could change how the condition is treated, providing more effective therapies where they are needed the most.

30 Jul 2015

Cryoport to offer cryogenic logistics solutions to HemaCare

Cryoport, Inc., the leading provider of advanced cryogenic logistics solutions for the life sciences industry, serving markets including immunotherapies, stem cells, cell lines, clinical research organizations, vaccine manufacturers, animal health, and reproductive medicine, today announced that the Company will provide cryogenic logistics solutions to HemaCare Corporation, a leading global provider of high-quality biological material to the scientific community.

30 Jul 2015

Intracellular microlasers may allow accurate measurement of small changes occurring within cells

Massachusetts General Hospital (MGH) investigators have induced structures incorporated within individual cells to produce laser light.

30 Jul 2015

DFG Senate Commission approves recommendations for developing clinical research at German universities

At the annual meeting of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) on 30 June 2015, the Senate of the largest research funding organisation approved recommendations for "Developing Clinical Research at German Universities Between 2015 and 2025" (available in German).

30 Jul 2015

HeartWare’s total revenues increase 13% to $73.6 million in second quarter 2015

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies that are revolutionizing the treatment of advanced heart failure, today announced total revenue of $73.6 million for the quarter ended June 30, 2015 compared to $70.1 million for the quarter ended June 30, 2014.

30 Jul 2015

More work needed to support consumers after enrolling in insurance plan under Affordable Care Act

Enrolling in an insurance plan under the Affordable Care Act is only the first step for consumers to be actively engaged in their health care, according to a new analysis from RAND Corporation researchers.

30 Jul 2015

Novel 3D human skin tissue model could help detect presence of known skin sensitizers in medical device extracts

New research shows that exposing a 3D human skin tissue model to extracts of medical device materials can detect the presence of sensitizers known to cause an allergic response on contact in some individuals. Conventional skin sensitization testing of medical devices relies on animal testing, whereas human skin models could replace animal methods, according to an article in the new journal Applied In Vitro Toxicology, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

30 Jul 2015

Research News and Research

Study shows why candidate vaccine used in HVTN 505 clinical trial not protective against HIV infection

Interactive Autism Network to join National Patient-Centered Clinical Research Network

DNA study reveals potential treatments to delay or prevent onset of Huntington's disease

Takeda completes post-marketing commitment and data submission for pioglitazone containing medicines

New blood test could help diagnose severity of traumatic brain injury

Researchers develop evidence-based model that can predict amount of nicotine released from e-cigarette

Female patients with depression have abnormally high expression levels of glutamate receptor genes

New Penn study questions relevance of fish oil-derived SPMs and their anti-inflammatory effects in humans

amfAR releases recommendations to help U.S. states to achieve goals of National HIV/AIDS Strategy

IU scientists find evidence that invisible war between microorganisms may affect human health

IUPUI researchers receive NIH grant to study effect of depression treatment on cardiovascular disease

Pharmacist-included medical care teams help patients better control blood pressure

GW Cancer Institute receives Eugene Washington PCORI Engagement Award to create online site for patient-centered care

Prostate cancer discovery may improve treatment strategies

Cryoport to offer cryogenic logistics solutions to HemaCare

Intracellular microlasers may allow accurate measurement of small changes occurring within cells

DFG Senate Commission approves recommendations for developing clinical research at German universities

HeartWare’s total revenues increase 13% to $73.6 million in second quarter 2015

More work needed to support consumers after enrolling in insurance plan under Affordable Care Act

Novel 3D human skin tissue model could help detect presence of known skin sensitizers in medical device extracts

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