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Study sheds light on certain antagonist drugs that block physiological responses

Members of the Consolidated Research Group of Molecular Neurobiology of the Department of Biochemistry and Molecular Biology of the University of Barcelona (UB), affiliated with the Centre for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), have published a study in the journal Proceedings of the National Academy of Sciences (PNAS) about the formation of G protein-coupled receptors (GPCRs) which allows understanding the unexpected behaviour of some antagonists that block physiological responses.

30 Jul 2015

Using physical processes to treat ships' ballast water can prevent spread of harmful organisms into local environment

Untreated ballast water discharge from ships can spread living organisms and even pathogens across the world thereby introducing non-native or invasive species into the local environment. Scientists at Helmholtz Zentrum München therefore recommend using physical treatment processes such as filtration rather than electrochemical disinfection, which creates countless potentially toxic compounds.

30 Jul 2015

Plants send out stress signals normally associated with animals

University of Adelaide research has shown for the first time that, despite not having a nervous system, plants use signals normally associated with animals when they encounter stress.

30 Jul 2015

Balancing cellular aging and cancer risk through biotechnology

In a way, trying to repair age-related heart damage and trying to fight cancer are opposite problems. Your heart cells' ability to regenerate themselves and proliferate into new, young cells degrades as you get older.

30 Jul 2015

Study reveals lingering effects of Superstorm Sandy among New Jersey residents

Superstorm Sandy continues to affect the lives of tens of thousands of New Jersey residents, in the form of unfinished repairs, disputed claims, and recurrent mold. These after-effects still linger for Sandy-impacted residents, and are associated with increased odds of residents experiencing mental health distress, post-traumatic stress disorder (PTSD), and depression.

30 Jul 2015

Researchers at Barrow Neurological Institute uncover brain surgery that changed history

Researchers at Barrow Neurological Institute have spent years of medical sleuthing across three continents to uncover a brain surgery that changed history.

30 Jul 2015

Research: Algae’s natural sunscreen molecules absorb UVA and UVB radiation with high efficiency

For consumers searching for just the right sunblock this summer, the options can be overwhelming. But scientists are now turning to the natural sunscreen of algae -- which is also found in fish slime -- to make a novel kind of shield against the sun's rays that could protect not only people, but also textiles and outdoor materials.

30 Jul 2015

Study on marine snails could help better understand underlying mechanisms of age-related memory loss

A new research study on marine snails uncovered the first cells in the nervous system to fail during aging. The University of Miami Rosenstiel School of Marine and Atmospheric Science researchers' findings are important to better understanding the underlying mechanisms of age-related memory loss in humans.

30 Jul 2015

New chemical reaction breaks strongest bond in molecules instead of weakest

Researchers at Princeton have developed a new chemical reaction that breaks the strongest bond in a molecule instead of the weakest, completely reversing the norm for reactions in which bonds are evenly split to form reactive intermediates.

30 Jul 2015

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

New research from Uppsala University shows promising progress in the use of anti-inflammatory cytokine for treatment of type 1 diabetes. The study, published in the open access journal Scientific Reports (Nature Publishing Group), reveals that administration of interleukin-35 (a protein made by immune cells) to mice with type 1 diabetes, reverses or cures the disease by maintaining a normal blood glucose level and the immune tolerance.

30 Jul 2015

Commonly prescribed drug also lowers blood pressure when combined with diuretic

With the growth of electronic medical records, research utilizing data from a large number of patients, known as big data studies, can provide important information which may be unattainable via clinical trials which tend to be costly, time-consuming and involve fewer patients.

30 Jul 2015

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been unknown. Publishing online in Endocrinology, Buck Institute assistant research professor Akos Gerencser, PhD, shows that in patients with type 2 diabetes the balance between supply and demand of the mitochondrial membrane potential (ΔψM) is altered causing a decrease in the signaling that turns on insulin secretion.

30 Jul 2015

Detailed molecular analyses reveal new treatment options for aggressive childhood leukemia

Acute lymphoblastic leukemia (ALL) leukemia is the most common type of cancer in children. It can occur in various forms, differing not only by specific changes in the genetic material of the leukemia cells but also by their response to therapies. Now, an international team of scientists from Berlin, Düsseldorf, Hannover, Heidelberg, Kiel, and Zurich have succeeded in decoding the molecular characteristics of an as yet incurable subtype of leukemia, paving the way for new therapeutic approaches.

30 Jul 2015

Articles explore mechanisms of repetitive thinking that contributes to mental health, illness

The ability to engage in mental time travel -- to delve back into past events or imagine future outcomes -- is a unique and central part of the human experience. And yet this very ability can have detrimental consequences for both physical and mental well-being when it becomes repetitive and uncontrolled.

30 Jul 2015

Cancer Research UK scientists identify five distinct types of prostate cancer

Cancer Research UK scientists have for the first time identified that there are five distinct types of prostate cancer and found a way to distinguish between them, according to a landmark study published today in EBioMedicine.

30 Jul 2015

Smaller doses of resveratrol more effective at preventing bowel cancer

Resveratrol, a chemical found in red grapes, is more effective in smaller doses at preventing bowel cancer in mice than high doses, according to new research published today (Wednesday) in the journal Science Translational Medicine.

30 Jul 2015

Race to meet EU biofuel targets could put human health at risk

The race to meet carbon-neutral biofuel targets could put human health and food crop production at risk unless it is carefully planned, according to new research.

30 Jul 2015

New set of clinical practice guidelines released to address temperature management during open heart surgery

The Society of Thoracic Surgeons, the Society of Cardiovascular Anesthesiologists, and the American Society of ExtraCorporeal Technology have released a set of clinical practice guidelines to address management of a patient's temperature during open heart surgery. The guidelines appear in the August issue of The Annals of Thoracic Surgery and were published simultaneously in two other journals.

30 Jul 2015

Finding by UCSF researchers could increase availability of kidneys for transplant

Mild hypothermia in deceased organ donors significantly reduces delayed graft function in kidney transplant recipients when compared to normal body temperature, according to UC San Francisco researchers and collaborators, a finding that could lead to an increase in the availability of kidneys for transplant.

30 Jul 2015

Pantheon announces acquisition of IBSL

Pantheon Holdco Ltd., doing business as the Pantheon Healthcare Group, announced today the acquisition of Ingegneria Biomedica Santa Lucia S.p.A., a key Italian-based provider of Clinical Engineering and a large range of biomedical equipment services, from Gruppo Giglio.

30 Jul 2015

Research News and Research

Study sheds light on certain antagonist drugs that block physiological responses

Using physical processes to treat ships' ballast water can prevent spread of harmful organisms into local environment

Plants send out stress signals normally associated with animals

Balancing cellular aging and cancer risk through biotechnology

Study reveals lingering effects of Superstorm Sandy among New Jersey residents

Researchers at Barrow Neurological Institute uncover brain surgery that changed history

Research: Algae’s natural sunscreen molecules absorb UVA and UVB radiation with high efficiency

Study on marine snails could help better understand underlying mechanisms of age-related memory loss

New chemical reaction breaks strongest bond in molecules instead of weakest

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

Commonly prescribed drug also lowers blood pressure when combined with diuretic

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Detailed molecular analyses reveal new treatment options for aggressive childhood leukemia

Articles explore mechanisms of repetitive thinking that contributes to mental health, illness

Cancer Research UK scientists identify five distinct types of prostate cancer

Smaller doses of resveratrol more effective at preventing bowel cancer

Race to meet EU biofuel targets could put human health at risk

New set of clinical practice guidelines released to address temperature management during open heart surgery

Finding by UCSF researchers could increase availability of kidneys for transplant

Pantheon announces acquisition of IBSL

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