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Inflammatory processes triggered by lung cancer could cause pulmonary hypertension

Shortness of breath and respiratory distress often increase the suffering of advanced-stage lung cancer patients. These symptoms can be triggered by pulmonary hypertension, as scientists at the Max Planck Institute for Heart and Lung Research in Bad Nauheim and the German Center for Lung Research found after examining more than 500 patients.

22 Nov 2017

OBD presents results of immunotherapy studies at FNIH Biomarker Consortium Cancer Steering Committee’s annual meeting

Oxford BioDynamics Plc, a biotechnology company focused on the discovery and development of epigenetic biomarkers based on regulatory genome architecture, for use within the pharmaceutical and biotechnology industry, presented its latest results at the annual meeting of the Foundation for National Institute for Health Biomarker Consortium Cancer Steering Committee, held in Washington, DC on 6-7 November 2017.

22 Nov 2017

Newly discovered drug-like compound may revolutionize treatment of autoimmune diseases

University of Colorado Boulder researchers have discovered a potent, drug-like compound that could someday revolutionize treatment of rheumatoid arthritis and other autoimmune diseases by inhibiting a protein instrumental in prompting the body to start attacking its own tissue.

21 Nov 2017

‘Chemo brain’ may start as tumors form and develop, suggests study

The memory and thinking problems experienced by cancer survivors, known as "chemo brain" or "chemo fog," are not just the result of chemotherapy treatment, they may start as tumors form and develop, suggests a Baycrest-led study.

21 Nov 2017

Diabetes patients’ immune system can regulate insulin production

Inflammation processes are responsible for the failure of insulin production in diabetes patients. The patients' own immune systems can contribute to treatment of this disease: researchers at the University of Basel and University Hospital Basel have found a feedback mechanism that could help maintain insulin production in overweight sufferers, as they report in the journal Immunity.

21 Nov 2017

New mechanism in cancer cells to disarm attacking immune cells, study reveals

A new study, published in the Journal of Clinical Investigation, identified a substance Gdf-15, which is secreted by pancreatic cancer cells and shields cancerous cells from attack by immune cells known as macrophages.

21 Nov 2017

Pioneering research project aims to develop better diagnostic tests for NAFLD

A pioneering European research project aims to lead to new diagnostic tests to assess patients with non-alcoholic fatty liver disease (NAFLD) and identify those most at risk for developing severe inflammation and liver scarring.

21 Nov 2017

Gut bacteria at young age can contribute to MS onset and progression, study suggests

Researchers at Rutgers Robert Wood Johnson Medical School published a study suggesting that gut bacteria at young age can contribute to Multiple sclerosis (MS) disease onset and progression.

21 Nov 2017

Maintaining adequate vitamin D may help prevent onset of inflammatory diseases

Maintaining sufficient vitamin D levels may help to prevent the onset of inflammatory diseases like rheumatoid arthritis, research led by the University of Birmingham has discovered.

21 Nov 2017

Heart rate variability measured by electrocardiogram can help differentiate bipolar from major depression

A groundbreaking Loyola Medicine study suggests that a simple 15-minute electrocardiogram could help a physician determine whether a patient has major depression or bipolar disorder.

21 Nov 2017

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

D. Brent Polk, MD, AGAF, an investigator at Children's Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for the study of tumor necrosis factor (TNF) and its role in inflammatory bowel disease (IBD).

20 Nov 2017

Cystic fibrosis patients have more good and bad bacteria in their lungs, study finds

A large multicenter study found that patients with cystic fibrosis (CF) – who tend to develop chronic lung infections – had more good and bad bacteria in their lungs compared to controls.

20 Nov 2017

Gut bacteria at young age can contribute to MS disease onset and progression, study suggests

Researchers at Rutgers Robert Wood Johnson Medical School published a study suggesting that gut bacteria at young age can contribute to Multiple sclerosis (MS) disease onset and progression.

17 Nov 2017

Old World monkeys could hold key to stop progression of rheumatoid arthritis

In the quest for a new and more effective treatment for rheumatoid arthritis, researchers from the Keck School of Medicine of USC looked to a primate that mostly roams the land in Asia, the Middle East and Africa.

17 Nov 2017

Researchers identify possible genetic basis for coronary artery disease

The buildup of plaque in the heart's arteries is an unfortunate part of aging. But by studying the genetic makeup of people who maintain clear arteries into old age, researchers led by UNC's Jonathan Schisler, PhD, have identified a possible genetic basis for coronary artery disease (CAD), as well as potential new opportunities to prevent it.

17 Nov 2017

FDA approves first adjuvant treatment to reduce risk of kidney cancer recurrence

The U.S. Food and Drug Administration today approved Sutent (sunitinib malate) for the adjuvant treatment of adult patients who are at a high risk of kidney cancer (renal cell carcinoma) returning after a kidney has been removed (nephrectomy).

17 Nov 2017

Brain astrocytes could play key role in pathogenesis of Alzheimer's disease

Astrocytes, the supporting cells of the brain, could play a significant role in the pathogenesis of Alzheimer's disease (AD), according to a new study from the University of Eastern Finland. This is the first time researchers discovered a direct association between astrocytes and AD. Published in Stem Cell Reports, the study investigated the brain cell function of familial AD patients by using stem cell technologies.

17 Nov 2017

New model to test effectiveness of existing and potential CF therapies

UNC School of Medicine researchers have developed a new laboratory model of the infection- and inflammation-plagued airways of cystic fibrosis (CF) patients.

17 Nov 2017

Environmental triggers may play role in development of Lupus

While genetics play a role in the development of Lupus, a systemic autoimmune disease that can attack any organ system in the human body, so do environmental triggers, such as particulates in air pollution and ultraviolet light, explains Gaurav Gulati, MD, a physician-researcher at the University of Cincinnati College of Medicine.

16 Nov 2017

Discovery of natural molecule could lead to effective treatments for gum disease and atherosclerosis

Resolvin E1, a molecule produced naturally in the body from an omega -3 fish oil, topically applied on gum tissues not only prevents and treats gum disease as previously shown (Hasturk et al 2006 and 2007), but also decreases the likelihood for advanced arterial atherosclerotic plaques to rupture and form a dangerous thrombus or blood clot.

16 Nov 2017

Inflammation News and Research

Inflammatory processes triggered by lung cancer could cause pulmonary hypertension

OBD presents results of immunotherapy studies at FNIH Biomarker Consortium Cancer Steering Committee’s annual meeting

Newly discovered drug-like compound may revolutionize treatment of autoimmune diseases

‘Chemo brain’ may start as tumors form and develop, suggests study

Diabetes patients’ immune system can regulate insulin production

New mechanism in cancer cells to disarm attacking immune cells, study reveals

Pioneering research project aims to develop better diagnostic tests for NAFLD

Gut bacteria at young age can contribute to MS onset and progression, study suggests

Maintaining adequate vitamin D may help prevent onset of inflammatory diseases

Heart rate variability measured by electrocardiogram can help differentiate bipolar from major depression

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

Cystic fibrosis patients have more good and bad bacteria in their lungs, study finds

Gut bacteria at young age can contribute to MS disease onset and progression, study suggests

Old World monkeys could hold key to stop progression of rheumatoid arthritis

Researchers identify possible genetic basis for coronary artery disease

FDA approves first adjuvant treatment to reduce risk of kidney cancer recurrence

Brain astrocytes could play key role in pathogenesis of Alzheimer's disease

New model to test effectiveness of existing and potential CF therapies

Environmental triggers may play role in development of Lupus

Discovery of natural molecule could lead to effective treatments for gum disease and atherosclerosis

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