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Steroids used for treating TB may reduce death rates from all types of TB

The routine use of steroids to treat tuberculosis may help reduce deaths from all types of the disease, according to a new review of existing research.

14 Mar 2013

Research findings have potential implications for treating human infections

Half of the world's human population is infected with the stomach bacteria called Helicobacter pylori, yet it causes disease in only about 10 percent of those infected. Other bacteria living in the stomach may be a key factor in whether or not H. pylori causes disease, according to a new study led by scientists at the University of California, Santa Cruz.

14 Mar 2013

Two faculty members find association between gum disease and obesity

Blood on your toothbrush can be a warning sign of gum disease. And, if you are overweight, it can indicate other serious health issues, such as diabetes, heart disease and high blood pressure.

13 Mar 2013

B cells regulate obesity-associated inflammation and T2D through two specific mechanisms

New research from Boston University School of Medicine (BUSM) reveals that B cells regulate obesity-associated inflammation and type 2 diabetes through two specific mechanisms.

13 Mar 2013

High-dose rosuvastatin reduces acute kidney injury caused by imaging dye in ACS patients

High doses of a popular cholesterol-lowering drug significantly reduced the rate of acute kidney injury caused by dye used in imaging in acute coronary syndrome patients who underwent a coronary procedure, according to research presented today at the American College of Cardiology's 62nd Annual Scientific Session.

12 Mar 2013

Laboratory for Molecular Biodiscovery, KU Leuven partner for €9.5M 'PharmaSea' project

KU Leuven scientist Camila Esguerra and the Laboratory for Molecular Biodiscovery are coordinating a €9.5 million, EU-funded project to collect and study marine microbes extracted from some of the ocean's deepest, most extreme - and as-yet-unexplored -biomes.

12 Mar 2013

IL-22 plays critical role in normal lung repair following influenza infection

Once the initial episode of influenza has passed, the chronic effects tend to be overlooked. The results of a new study indicate that the cytokine interleukin-22 (IL-22) plays a critical role in normal lung repair following influenza infection. This study is published in the April 2013 issue of the American Journal of Pathology.

11 Mar 2013

Mummies provide important twist in understanding atherosclerotic vascular disease

Like nearly 4.6 million Americans, ancient hunter-gatherers also suffered from clogged arteries, revealing that the plaque build-up causing blood clots, heart attacks and strokes is not just a result of fatty diets or couch potato habits, according to new research in the journal The Lancet.

11 Mar 2013

Transfusion of older blood adversely affects patients undergoing cardiac surgery or critical care

Transfusion of donated blood more than three weeks old results in impaired blood vessel function, a new study of hospital patients shows.

11 Mar 2013

Weight loss may help prevent and alleviate symptoms of osteoarthritis

Weight loss may prevent and significantly alleviate the symptoms of osteoarthritis, a progressive disease of the joints known as "wear and tear" arthritis, according to a literature review appearing in the March 2013 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS).

11 Mar 2013

Aspirin's anti-inflammatory effects may help protect against melanoma

A new study has found that women who take aspirin have a reduced risk of developing melanoma-and that the longer they take it, the lower the risk. The findings suggest that aspirin's anti-inflammatory effects may help protect against this type of skin cancer. The study is published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

11 Mar 2013

Researchers identify enzymes that can regulate activity of medically important proteins

Protein activity is strictly regulated. Incorrect or poor protein regulation can lead to uncontrolled growth and thus cancer or chronic inflammation. Members of the Institute of Veterinary Biochemistry and Molecular Biology from the University of Zurich have identified enzymes that can regulate the activity of medically important proteins.

11 Mar 2013

Inclacumab reduces damage to heart muscle during angioplasty

A single dose of an investigational anti-inflammatory drug called inclacumab considerably reduces damage to heart muscle during angioplasty (the opening of a blocked artery), according to a recent international clinical trial spearheaded by Dr. Jean-Claude Tardif, Director of the Research Centre at the Montreal Heart Institute, affiliated with the University of Montreal.

11 Mar 2013

Investigational treatment for ulcerative colitis (UC) and Crohn’s disease (CD) has Marketing Authorisation Application submitted

Takeda Pharmaceutical Company Limited (“Takeda”) today announced that a Marketing Authorisation Application (MAA) has been submitted to The European Medicines Agency (EMA) for vedolizumab, an investigational, gut-selective humanized monoclonal antibody for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn’s disease (CD), the two most common types of inflammatory bowel disease (IBD).

8 Mar 2013

Chronic obstructive pulmonary disease (COPD) inflammatory subtypes: an interview with Dr Vanessa McDonald, University of Newcastle, Australia

COPD is defined as a preventable and treatable disease associated with significant extrapulmonary consequences that may contribute to severity. The pulmonary component of COPD is characterised by airflow limitation that is not fully reversible. The airflow limitation is usually progressive with an abnormal inflammatory response of the lungs to noxious particles (GOLD Strategy Document). Airflow obstruction in COPD is not highly variable and largely irreversible.

8 Mar 2013

Patients with PTSD more likely to develop insulin resistance, metabolic syndrome and heart disease

Patients diagnosed with post-traumatic stress disorder (PTSD) have a significantly higher risk of developing insulin resistance and metabolic syndrome, placing them at greater risk for heart disease and diabetes, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session. Researchers say public health interventions are urgently needed to prevent PTSD-related metabolic disorder at its early, reversible stage.

8 Mar 2013

Southeast Asia's commercial trade plays a central role in spread of amphibian pathogens

A team of scientists led by the Wildlife Conservation Society (WCS) and the National University of Singapore (NUS), revealed in a new study, for the first time, the presence of the pathogenic chytrid fungus (Batrachochytrium dendrobatidis) in amphibians sampled in Singapore. And the American bullfrog may be a central player in the spread of the disease.

8 Mar 2013

Insight into how Th17 cell growth influences development of immune responses

New work from the Broad Institute's Klarman Cell Observatory, Brigham and Women's Hospital, Harvard University, MIT, and Yale University expands the understanding of how one type of immune cell - known as a T helper 17 or Th17 cell - develops, and how its growth influences the development of immune responses.

7 Mar 2013

Study investigates how cancer cells 'hijack' platelets

A new research study has investigated how cancer cells 'hijack' blood cells known as platelets, enabling cancer to spread around the body and promoting the growth of new tumours, it was reported today at the annual Royal College of Surgeons in Ireland (RCSI) Research Day.

7 Mar 2013

University of Manchester leads systems medicine research network for inflammatory bowel disease

The University of Manchester is leading a €12 million systems medicine research network to identify better treatments for Inflammatory Bowel Disease like Crohn's Disease.

6 Mar 2013

Inflammation News and Research

Steroids used for treating TB may reduce death rates from all types of TB

Research findings have potential implications for treating human infections

Two faculty members find association between gum disease and obesity

B cells regulate obesity-associated inflammation and T2D through two specific mechanisms

High-dose rosuvastatin reduces acute kidney injury caused by imaging dye in ACS patients

Laboratory for Molecular Biodiscovery, KU Leuven partner for €9.5M 'PharmaSea' project

IL-22 plays critical role in normal lung repair following influenza infection

Mummies provide important twist in understanding atherosclerotic vascular disease

Transfusion of older blood adversely affects patients undergoing cardiac surgery or critical care

Weight loss may help prevent and alleviate symptoms of osteoarthritis

Aspirin's anti-inflammatory effects may help protect against melanoma

Researchers identify enzymes that can regulate activity of medically important proteins

Inclacumab reduces damage to heart muscle during angioplasty

Investigational treatment for ulcerative colitis (UC) and Crohn’s disease (CD) has Marketing Authorisation Application submitted

Chronic obstructive pulmonary disease (COPD) inflammatory subtypes: an interview with Dr Vanessa McDonald, University of Newcastle, Australia

Patients with PTSD more likely to develop insulin resistance, metabolic syndrome and heart disease

Southeast Asia's commercial trade plays a central role in spread of amphibian pathogens

Insight into how Th17 cell growth influences development of immune responses

Study investigates how cancer cells 'hijack' platelets

University of Manchester leads systems medicine research network for inflammatory bowel disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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