Neuroscience News and Research

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PKCI/HINT1 gene associated with mood regulation

Removing the PKCI/HINT1 gene from mice has an anti-depressant-like and anxiolytic-like effect. Researchers writing in the open access journal BMC Neuroscience applied a battery of behavioral tests to the PKCI/HINT1 knockout animals, concluding that the deleted gene may have an important role in mood regulation.

13 Nov 2009

Health Canada approves ONGLYZA for type 2 diabetes treatment

Bristol-Myers Squibb Canada and AstraZeneca Canada today announced that Health Canada has approved ONGLYZA(TM) (saxagliptin) which improves all three key measures of glycemic control - hemoglobin A1c (A1c), fasting plasma glucose (FPG) and post-prandial glucose (PPG) - when taken in combination with other commonly used oral anti-diabetic agents (metformin or a sulfonylurea).

13 Nov 2009

Mouth: A diagnostic indicator for general health

The mouth or oral cavity area is an excellent indicator of the whole body's health, says Mao, who is the chair of the new Department of Oncology and Diagnostic Sciences at the School.

13 Nov 2009

Transcept Pharmaceuticals reports financial results for the third quarter of 2009

Transcept Pharmaceuticals, Inc., a specialty pharmaceutical company focused on the development and commercialization of proprietary products that address important therapeutic needs in neuroscience, today announced financial results for the three and nine months ended September 30, 2009.

13 Nov 2009

Jonathan Richman to present at FDA public hearing on promoting medical devices using the Internet

Bridge Worldwide announced today that Jonathan Richman, Director of Strategic Planning, will present at the public hearing on "Promotion of FDA-Regulated Medical Products Using the Internet and Social Media Tools," to be held on November 12 and 13, 2009, from 8 a.m. to 5 p.m., at the National Transportation Safety Board Conference Center in Washington, D.C. Richman is scheduled to speak on Friday, November 13, at 11:40 a.m. and 2:40 p.m. for 10 minutes per time slot. To listen to a free, live webcast of the hearing, go to: www.capitolconnection.net/capcon/fda/111209/FDAlive.htm.

12 Nov 2009

Researchers identify mouse gene that reduces the accumulation Alzheimer's plaques and tangles

Investigators at Burnham Institute for Medical Research (Burnham) and colleagues have identified a novel mouse gene (Rps23r1) that reduces the accumulation of two toxic proteins that are major players in Alzheimer's disease: amyloid beta and tau. The amyloid and tau lowering functions of this gene were demonstrated in both human and mouse cells.

12 Nov 2009

Children with developmental dyslexia have difficulties separating relevant auditory information from irrelevant noise

The vast majority of school-aged children can focus on the voice of a teacher amid the cacophony of the typical classroom thanks to a brain that automatically focuses on relevant, predictable and repeating auditory information, according to new research from Northwestern University.

12 Nov 2009

Researchers find link between telomeres and longevity

A team led by researchers at Albert Einstein College of Medicine of Yeshiva University has found a clear link between living to 100 and inheriting a hyperactive version of an enzyme that rebuilds telomeres - the tip ends of chromosomes. The findings appear in the latest issue of the Proceedings of the National Academy of Sciences.

12 Nov 2009

New robotic surgical systems from El Camino Hospital

El Camino Hospital, the hospital of Silicon Valley, expands its minimally invasive surgical program to three da Vinci® Si HD Surgical Systems. Physicians performed more than 500 robotic surgeries over the past year and expect the number to increase in 2010 as more physicians undergo training with the enhanced equipment that allows for more minimally invasive procedures.

11 Nov 2009

Researchers identify new mechanism to create lasting memories; findings may yield potential treatment for memory impairments

Researchers at the Swedish medical university Karolinska Institutet have discovered a mechanism that controls the brain's ability to create lasting memories. In experiments on genetically manipulated mice, they were able to switch on and off the animals' ability to form lasting memories by adding a substance to their drinking water. The findings, which are published in the scientific journal PNAS, are of potential significance to the future treatment of Alzheimer's and stroke.

11 Nov 2009

New insight into how brain responds when people experience an unexpected or traumatic event

In a new study, psychologists at the University of Alabama at Birmingham (UAB) are able to see in detail for the first time how various regions of the human brain respond when people experience an unexpected or traumatic event. The study could lead to the creation of biological measures that could identify people with post-traumatic stress disorder (PTSD) or identify PTSD sufferers who would benefit from specific treatments.

11 Nov 2009

HFSP grant to develop molecular probes to study "cellular GPS" system

An international group of researchers from Carnegie Mellon University, Goettingen Medical School in Germany and the University of Cambridge in the United Kingdom have received a Human Frontiers Science Program (HFSP) grant to develop molecular probes that will help researchers better understand the "cellular GPS" system that guides neurons to create a properly wired nervous system.

11 Nov 2009

Veterans don't ask for psychological help

They've seen horrors, experienced constant threats and survived traumatic events. Canada's military personnel often come back home with memories they'd rather forget. It's not scientifically understood why some soldiers develop post-traumatic stress disorder (PTSD) while others don't. However, many veterans simply don't ask for psychological help.

10 Nov 2009

Astellas receives exclusive rights to develop and commercialize linaclotide compound in Asia

Ironwood Pharmaceuticals, Inc. and Astellas Pharma Inc. today announced that they have entered into an agreement providing Astellas exclusive rights to develop and commercialize the investigational compound linaclotide in Japan, Indonesia, Korea, the Philippines, Taiwan, and Thailand.

10 Nov 2009

Recollections of traumatic incidents can be controlled

It is well known that fear memories are permanent. However, a recent paper in Science, evaluated by three Faculty Members for F1000, reports an extraordinary finding that supports the use of a drug to control recollections of traumatic incidents.

10 Nov 2009

Teenage women who are obese at higher risk to develop MS as adults

Teenage women who are obese may be more than twice as likely to develop multiple sclerosis (MS) as adults compared to female teens who are not obese, according to a study published in the November 10, 2009, print issue of Neurology-, the medical journal of the American Academy of Neurology.

10 Nov 2009

Three IVF attempts increase chances of a live birth

Just one in three women gives birth after a single IVF attempt, but the cumulative chance of a live birth increases with each cycle - where women are offered three cycles nearly two thirds go on to have babies, reveals a thesis from the Sahlgrenska Academy at the University of Gothenburg in Sweden.

10 Nov 2009

Children with autism may have lower quality handwriting, says study

Children with autism may have lower quality handwriting and trouble forming letters compared to children without autism, according to a study published in the November 10, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.

9 Nov 2009

Military personnel with back pain unlikely to return to duty after treatment

Military personnel evacuated out of Iraq and Afghanistan because of back pain are unlikely to return to the line of duty regardless of the treatment they receive, according to research led by a Johns Hopkins pain management specialist.

9 Nov 2009

BrainStorm Cell Therapeutics' approach for treating neurodegenerative diseases shown to be effective

BrainStorm Cell Therapeutics Inc., a leading developer of adult stem cell technologies and therapeutics, is pleased to announce that the company’s therapeutic approach for treating neurodegenerative diseases was shown to be superior to other current potential stem cell treatments.

9 Nov 2009

Neuroscience News and Research

PKCI/HINT1 gene associated with mood regulation

Health Canada approves ONGLYZA for type 2 diabetes treatment

Mouth: A diagnostic indicator for general health

Transcept Pharmaceuticals reports financial results for the third quarter of 2009

Jonathan Richman to present at FDA public hearing on promoting medical devices using the Internet

Researchers identify mouse gene that reduces the accumulation Alzheimer's plaques and tangles

Children with developmental dyslexia have difficulties separating relevant auditory information from irrelevant noise

Researchers find link between telomeres and longevity

New robotic surgical systems from El Camino Hospital

Researchers identify new mechanism to create lasting memories; findings may yield potential treatment for memory impairments

New insight into how brain responds when people experience an unexpected or traumatic event

HFSP grant to develop molecular probes to study "cellular GPS" system

Veterans don't ask for psychological help

Astellas receives exclusive rights to develop and commercialize linaclotide compound in Asia

Recollections of traumatic incidents can be controlled

Teenage women who are obese at higher risk to develop MS as adults

Three IVF attempts increase chances of a live birth

Children with autism may have lower quality handwriting, says study

Military personnel with back pain unlikely to return to duty after treatment

BrainStorm Cell Therapeutics' approach for treating neurodegenerative diseases shown to be effective

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