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FDA approves Rybrevant for treating subset of non-small cell lung cancer

Today, the U.S. Food and Drug Administration approved Rybrevant (amivantamab-vmjw) as the first treatment for adult patients with non-small cell lung cancer whose tumors have specific types of genetic mutations: epidermal growth factor receptor (EGFR) exon 20 insertion mutations.

21 May 2021

Trial results show upadacitinib to be the most effective treatment for atopic dermatitis

The findings of a clinical trial by Trinity College Dublin researchers of treatment for atopic dermatitis have been published today in The Lancet journal (Friday, 21st May, 2021).

21 May 2021

Distribution of lithium in the brain plays key role in depressive disorders

Depressive disorders are among the most frequent illnesses worldwide. The causes are complex and to date only partially understood. The trace element lithium appears to play a role.

21 May 2021

As pandemic eases, many seniors have lost strength, may need rehabilitative services

Ronald Lindquist, 87, has been active all his life. So, he wasn't prepared for what happened when he stopped going out during the coronavirus pandemic and spent most of his time, inactive, at home.

21 May 2021

Worried brains can be retrained to think positive, shows new study

Worried brains can be retrained to respond to everyday situations in a less threatening way to reduce anxiety levels, according to new research published by researchers from The University of Western Australia and the University of Virginia.

21 May 2021

New study may lead to better treatments for prostate, ovarian, and breast cancers

Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells – and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers.

21 May 2021

Metal complexes against coronavirus

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused more than 3.42 million deaths worldwide. Despite the fact that there are vaccines for SARS-CoV-2, the emergence of new variants and the lack of adequate treatments have encouraged the search for new ways to combat this disease more effectively.

21 May 2021

Adaptimmune to report Phase 2 trial data on synovial sarcoma at ASCO congress

Adaptimmune Therapeutics plc, a leader in cell therapy to treat cancer, will report initial data from its Phase 2 SPEARHEAD-1 trial, with afamitresgene autoleucel (afami-cel, formerly ADP-A2M4), at the American Society of Clinical Oncology (ASCO) congress. Full abstracts were released online today.

21 May 2021

Asthma patients can benefit from type 2 diabetes medication

Type 2 diabetes patients who also have asthma are benefitting from a diabetes medication, typically given to help the pancreas produce more insulin, that also improves asthma symptoms and may reduce lung and airway inflammation.

21 May 2021

Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

Two experimental drug approaches that target vulnerabilities in cancer cell metabolism may extend survival and enhance the effectiveness of standard chemotherapies for a highly aggressive type of pediatric brain cancer.

21 May 2021

Intranasal COVID-19 therapeutic shows promise in preclinical trials

Researchers from the US and Denmark recently described a novel therapeutic option that targets the SARS-CoV-2 ribonucleic acid (RNA) using locked nucleic acid antisense oligonucleotides (LNA ASOs). They identified an LNA ASO that binds to the 5’ leader sequence of SARS-CoV-2 ORF1a/b. This disrupts a highly conserved stem-loop structure with nanomolar efficacy and inhibits viral replication in host cells.

20 May 2021

Scientists discover key component to repair the molecular motor of human heart

A team of scientists from Loyola University Chicago's Stritch School of Medicine have discovered a critical component for renewing the heart's molecular motor, which breaks down in heart failure.

20 May 2021

Cancer occurs through multiple steps that resurrect ancient cellular functions, suggests new model

In spite of decades of research, cancer remains an enigma. Conventional wisdom holds that cancer is driven by random mutations that create aberrant cells that run amok in the body.

20 May 2021

Phase 3 trial: New biologic therapy improves outcomes in adults, adolescents with severe asthma

Results from the NAVIGATOR study of tezepelumab showed that the new biologic therapy significantly reduced exacerbations requiring hospital stays and emergency department (ED) visits for adults and adolescents with severe, uncontrolled asthma, according to research presented at the ATS 2021 International Conference.

20 May 2021

Seniors enrolled in both Medicare and Medicaid can experience worse outcomes after ICU hospitalization

Seniors who are enrolled in both Medicare and Medicaid are at risk for experiencing greater worsening of functional status following ICU hospitalization, according to research presented at the ATS 2021 International Conference.

20 May 2021

A better understanding of brain fluid movements can help predict and treat Alzheimer's disease

Scientists don't fully understand what causes Alzheimer's disease, but they have a primary suspect.

20 May 2021

Triple-drug therapy can reduce asthma exacerbations, improve control without major adverse events

Researchers have found that the inclusion of a third drug to commonly used dual-drug inhalers can reduce asthma exacerbations and improve control over the disease in children, adolescents, and adults with moderate-to-severe asthma.

20 May 2021

Four months of multi-drug therapy for tuberculosis is as effective as standard regimen

Four months of multi-drug therapy that included rifapentine and moxifloxacin treated active tuberculosis (TB) as effectively as the standard six-month regimen in a multinational study, cutting treatment time by a third.

20 May 2021

Study could serve as guidepost for developing new therapies for Alzheimer's disease

In a major breakthrough, researchers at Massachusetts General Hospital (MGH) have discovered how amyloid beta--the neurotoxin believed to be at the root of Alzheimer's disease (AD)--forms in axons and related structures that connect neurons in the brain, where it causes the most damage.

20 May 2021

Monoclonal antibody bamlanivimab reduces hospitalization and death in moderate-to-severe COVID-19

Researchers at the University of Pittsburgh School of Medicine and the University of Pittsburgh Medical Center found that monoclonal antibodies, a COVID-19 treatment administered early after infection, reduce the risk of hospitalization and death by 60 percent in people at high risk of suffering complications from the condition.

20 May 2021

Therapy News and Research

FDA approves Rybrevant for treating subset of non-small cell lung cancer

Trial results show upadacitinib to be the most effective treatment for atopic dermatitis

Distribution of lithium in the brain plays key role in depressive disorders

As pandemic eases, many seniors have lost strength, may need rehabilitative services

Worried brains can be retrained to think positive, shows new study

New study may lead to better treatments for prostate, ovarian, and breast cancers

Metal complexes against coronavirus

Adaptimmune to report Phase 2 trial data on synovial sarcoma at ASCO congress

Asthma patients can benefit from type 2 diabetes medication

Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

Intranasal COVID-19 therapeutic shows promise in preclinical trials

Scientists discover key component to repair the molecular motor of human heart

Cancer occurs through multiple steps that resurrect ancient cellular functions, suggests new model

Phase 3 trial: New biologic therapy improves outcomes in adults, adolescents with severe asthma

Seniors enrolled in both Medicare and Medicaid can experience worse outcomes after ICU hospitalization

A better understanding of brain fluid movements can help predict and treat Alzheimer's disease

Triple-drug therapy can reduce asthma exacerbations, improve control without major adverse events

Four months of multi-drug therapy for tuberculosis is as effective as standard regimen

Study could serve as guidepost for developing new therapies for Alzheimer's disease

Monoclonal antibody bamlanivimab reduces hospitalization and death in moderate-to-severe COVID-19

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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