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Chemo-immunotherapy combination shows promise against pancreatic cancer

A combination of chemotherapy with an immunotherapy meant to unleash the anticancer capacity of the immune system was effective against one of the hardest targets in cancer care, pancreatic cancer, in a national, randomized clinical trial led by researchers at the Perelman School of Medicine at the University of Pennsylvania, and sponsored by the Parker Institute for Cancer Immunotherapy.

6 Jun 2022

Electronic symptom monitoring improved quality-of-life outcomes among patients with metastatic cancer

People with advanced cancer who communicated their symptoms weekly using an electronic survey had about a one-third better physical function and over a 15% better control of their symptoms compared to those who were evaluated less frequently via in-person clinical visits, according to findings from a multi-state study conducted at 52 community cancer clinics.

6 Jun 2022

Hospice patients with dementia more likely to receive excellent care, study shows

While the hospice program was originally designed for patients with cancer, who are expected to die within six months, currently close to half of older adult hospice enrollees have a diagnosis of dementia.

6 Jun 2022

Short 20-minute power naps during night shifts can help improve hospital staff and patient safety

A review at this year's Euroanaesthesia congress in Milan, Italy (4-6 June) on the potentially lethal effects of fatigue on doctors and nurses themselves, and its impact on the quality of their clinical work and judgment and therefore patient safety, will be given by Consultant Anaesthetist Dr Nancy Redfern of Newcastle Hospitals NHS Foundation Trust, Newcastle, UK.

6 Jun 2022

Infants exposed to COVID-19 in the womb exhibit differences in neurodevelopmental outcomes

Babies born to mothers who suffered COVID-19 disease during pregnancy seem to exhibit differences in neurodevelopmental outcomes at 6 weeks, according to a preliminary analysis presented in the 30th European Congress of Psychiatry.

6 Jun 2022

Drug combination yields highest response and longest survival rates for patients with pancreatic NETs

Very few treatment options are available to patients with advanced pancreatic neuroendocrine tumors (NETs), but researchers at the Yale Cancer Center and Yale New Haven Health's Smilow Cancer Hospital found that patients treated with a combination of capecitabine and temozolomide had longer progression-free survival rates than those treated with temozolomide alone.

6 Jun 2022

Long-term exposure to air pollution associated with greater risk of severe COVID-19

Long-term exposure to air pollution is linked to a greater risk of severe COVID-19, new research being presented at Euroanaesthesia, the annual meeting of the European Society of Anaesthesiology and Intensive Care (ESAIC) in Milan, Italy (4-6 June), finds.

6 Jun 2022

She’s 31, has stage 4 kidney cancer — and talked openly about it in a job interview

Katie Coleman stood face-to-face with a choice no job seeker should ever have to make. She could tell her prospective employer she had stage 4 kidney cancer, the most life-threatening stage of all.

6 Jun 2022

Addressing the ‘trust factor’: South Carolina researchers tackle health disparities using genetics

Quenton Tompkins' family tree is deeply rooted in rural McCormick County, South Carolina.

6 Jun 2022

COVID-19's economic impact on healthcare systems, societies, and the population

In a recent study review posted to the medRxiv* preprint server, researchers evaluated the economic and medical costs incurred due to the coronavirus disease 2019 (COVID-19) pandemic.

6 Jun 2022

Taking everolimus post-surgery can improve outcomes in patients with high-risk renal cell carcinoma

In a study of patients with high-risk renal cell carcinoma, those who took the drug everolimus daily for up to one year after surgery lived longer without their disease returning (recurrence-free survival, or RFS) than those who did not take everolimus, although the results narrowly missed the clinical trial's prespecified level for statistical significance.

4 Jun 2022

Weight loss with bariatric surgery associated with lower risk of cancer and cancer-related mortality

A Cleveland Clinic study shows that among adults with obesity, weight loss achieved with bariatric surgery was associated with a 32% lower risk of developing cancer and a 48% lower risk of cancer-related death compared with adults who did not have the surgery.

3 Jun 2022

Research may help move bone regeneration research from laboratories to medical use

Your chance of breaking a bone sometime within the next year is nearly 4%. If you're unlucky enough to need a bone replacement, it'll probably be based on a metal part.

3 Jun 2022

Researchers evaluate how hundreds of different mutations impact key function of breast cancer gene

Inherited mutations in the BRCA1 gene can significantly increase a person's risk of breast and ovarian cancer - but not every mutation in the gene is harmful.

3 Jun 2022

Researchers repurpose a cancer drug for the treatment of neuroinflammatory diseases

The repurposing of FDA-approved drugs for alternative diseases is a faster way of bringing new treatments into the clinic.

3 Jun 2022

New guidelines recommend pancreatic cancer screening for individuals with genetic susceptibility

By the year 2030, pancreatic cancer is expected to become the second most common cause of cancer deaths for both men and women in the United States, according to recent reports.

3 Jun 2022

Novel approach identifies potent drug-like molecules that bind to cancer protein of interest

Researchers at Baylor College of Medicine and Texas Children's Hospital have identified potent, highly specific compounds that interfere with bromodomain (BD)-containing proteins involved in cancer.

3 Jun 2022

Study uncovers differences in genetic mutations between younger and older breast cancer patients

Women younger than 40 years of age with advanced breast cancer often suffer from more aggressive disease and worse prognoses than their older counterparts.

3 Jun 2022

Study: Nearly 43% of patients with KRAS-mutated lung cancer respond to experimental drug adagrasib

Nearly 43% of patients with non-small cell lung cancer (NSCLC) whose lung cancers harbored a specific KRAS mutation responded to the experimental drug adagrasib, and the targeted agent also showed activity against lesions in the brain that metastasized from the lung tumors, according to results of a study led by Dana-Farber Cancer Institute investigators.

3 Jun 2022

New immunotherapy mechanism can block spontaneous breast carcinogenesis

Researchers have discovered the mechanism by which specific immune cells can block breast cancer development and even suppress a developed tumor.

3 Jun 2022

Hospital News and Research

Chemo-immunotherapy combination shows promise against pancreatic cancer

Electronic symptom monitoring improved quality-of-life outcomes among patients with metastatic cancer

Hospice patients with dementia more likely to receive excellent care, study shows

Short 20-minute power naps during night shifts can help improve hospital staff and patient safety

Infants exposed to COVID-19 in the womb exhibit differences in neurodevelopmental outcomes

Drug combination yields highest response and longest survival rates for patients with pancreatic NETs

Long-term exposure to air pollution associated with greater risk of severe COVID-19

She’s 31, has stage 4 kidney cancer — and talked openly about it in a job interview

Addressing the ‘trust factor’: South Carolina researchers tackle health disparities using genetics

COVID-19's economic impact on healthcare systems, societies, and the population

Taking everolimus post-surgery can improve outcomes in patients with high-risk renal cell carcinoma

Weight loss with bariatric surgery associated with lower risk of cancer and cancer-related mortality

Research may help move bone regeneration research from laboratories to medical use

Researchers evaluate how hundreds of different mutations impact key function of breast cancer gene

Researchers repurpose a cancer drug for the treatment of neuroinflammatory diseases

New guidelines recommend pancreatic cancer screening for individuals with genetic susceptibility

Novel approach identifies potent drug-like molecules that bind to cancer protein of interest

Study uncovers differences in genetic mutations between younger and older breast cancer patients

Study: Nearly 43% of patients with KRAS-mutated lung cancer respond to experimental drug adagrasib

New immunotherapy mechanism can block spontaneous breast carcinogenesis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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