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Umeå University researchers capture and describe 'invisible' protein structure

A research group at Umeå University in Sweden has managed to capture and describe a protein structure that, until now, has been impossible to study. The discovery lays the base for developing designed enzymes as catalysts to new chemical reactions for instance in biotechnological applications.

3 Jul 2015

Researchers receive 2.6 million euros to study evolution of sexual reproduction in plants

A European and US consortium coordinated by Jorg Becker, group leader at the Instituto Gulbenkian de Ciencia (IGC; Portugal), has now received funding of 2.6 million euros for 3 years to study the evolution of sexual reproduction in plants. The project is funded under the scope of ERA-CAPS, a European network dedicated to support research activities in Plant Sciences.

3 Jul 2015

Study: New test may help predict effectiveness of biologic drugs in RA patients

A study of 311 patients by The University of Manchester has found that it may be possible to predict early which rheumatoid arthritis (RA) patients will fail to respond to the biologic drugs given to treat them.

3 Jul 2015

Two new studies show that fecal transplantation may help fight against ulcerative colitis

Two new studies led by researchers from the Farncombe Family Digestive Health Research Institute at McMaster University show that transplantation of fecal matter may be a useful tool in the fight against ulcerative colitis (UC).

3 Jul 2015

Researchers compare effectiveness of two stem cell types in treating retinal degeneration

By growing two types of stem cells in a "3-D culture" and measuring their ability to produce retinal cells, a team lead by St. Jude Children's Research Hospital researchers has found one cell type to be better at producing retinal cells.

3 Jul 2015

Gene therapy improves lung function in patients with cystic fibrosis

Gene therapy was shown to provide significant benefits for patients with cystic fibrosis in a recent clinical study published in The Lancet Respiratory Medicine journal.

3 Jul 2015

Phase IIIb CONSIGN study confirms benefit of regorafenib in patients with pre-treated mCRC

The phase IIIb CONSIGN study has confirmed the benefit of regorafenib in patients with previously treated metastatic colorectal cancer (mCRC), researchers announced at the ESMO 17th World Congress on Gastrointestinal Cancer 2015 in Barcelona.

3 Jul 2015

Imaging proteasome complex helps show target site for potential cancer drugs

Scientists have pioneered the use of a high-powered imaging technique to picture in exquisite detail one of the central proteins of life - a cellular recycling unit with a role in many diseases.

3 Jul 2015

GPS devices help dementia sufferers achieve increased sense of security, quality of life

A brand new study of 200 dementia sufferers in Norway reveals that almost all experience greater peace of mind and increased levels of physical activity using GPS devices.

3 Jul 2015

Increased food energy supply contributes to global obesity epidemic, shows study

Obesity – a global health problem – is increasing in many countries in step with increases in the food energy supply, according to a study published in the Bulletin of the World Health Organization today.

3 Jul 2015

Scientists find way to create therapeutic heat to treat people suffering from chronic muscle pain

If you suffer from chronic muscle pain a doctor will likely recommend for you to apply heat to the injury. But how do you effectively wrap that heat around a joint? Korean Scientists at the Center for Nanoparticle Research, Institute for Basic Science in Seoul, along with an international team, have come up with an ingenious way of creating therapeutic heat in a light, flexible design.

3 Jul 2015

Gene therapy for cystic fibrosis shows significant benefit in lung function

For the first time gene therapy for cystic fibrosis has shown a significant benefit in lung function compared with placebo, in a phase 2 randomised trial published in The Lancet Respiratory Medicine journal. The technique replaces the defective gene response for cystic fibrosis by using inhaled molecules of DNA to deliver a normal working copy of the gene to lung cells.

3 Jul 2015

Creating more effective vaccines against flu virus

Flu vaccines can be something of a shot in the dark. Not only must they be given yearly, there's no guarantee the strains against which they protect will be the ones circulating once the season arrives. New research by Rockefeller University scientists and their colleagues suggests it may be possible to harness a previously unknown mechanism within the immune system to create more effective and efficient vaccines against this ever-mutating virus.

3 Jul 2015

Study: Genes may not trigger heart disease in people suffering from migraine with aura

A new study suggests that genes may not be to blame for the increased risk of heart disease some studies have shown in people with migraine, especially those with migraine with aura. The research is published during Headache/Migraine Awareness Month in the inaugural issue of the journal Neurology Genetics, an open access, or free to the public, online-only, peer-reviewed journal from the American Academy of Neurology.

3 Jul 2015

Penn study suggests future precision medicine approach to treating diabetes, other metabolic disorders

In the first study of its kind, Penn researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals. Mitchell Lazar, MD, PhD, Raymond Soccio, MD, PhD, and colleagues at the Perelman School of Medicine at the University of Pennsylvania, aim to apply this knowledge to develop personalized approaches to treating diabetes and other metabolic disorders.

3 Jul 2015

Research shows how prion-like proteins critical for maintaining long-term memories

Research from Eric Kandel's lab at Columbia University Medical Center has uncovered further evidence of a system in the brain that persistently maintains memories for long periods of time. And paradoxically, it works in the same way as mechanisms that cause mad cow disease, kuru, and other degenerative brain diseases.

3 Jul 2015

Research finding could lead to first effective therapies, vaccines against dengue virus

Researchers at Vanderbilt University and the National University of Singapore have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue virus.

3 Jul 2015

NDSU's Stephen O'Rourke awarded NIH grant to conduct cardiovascular research

Stephen O'Rourke, professor of pharmaceutical sciences at North Dakota State University, Fargo, has received a $435,000 grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to conduct cardiovascular research.

3 Jul 2015

Review article provides in depth survey of studies focusing on retinoblastoma protein's role in apoptosis

Retinoblastoma protein RB1, which is named after a form of pediatric tumor of the eye, is among the most common genetically regulated cellular proteins to malfunction in human cancer. RB1 was also the first tumor suppressor gene to be identified and its modes of inactivation in retinoblastoma tumors provided the basis for the ground-breaking two-hit hypothesis by the geneticist Alfred G. Knudson in the 70s, according to which cancer is due to the accumulation of multiple 'hits' or mutations in certain genes.

3 Jul 2015

Combination of exercise and artificial gravity may reduce effects of extended weightlessness in space

Astronauts on the International Space Station have a number of exercise options, including a mechanical bicycle bolted to the floor, a weightlifting machine strapped to the wall, and a strap-down treadmill. They spend a significant portion of each day working out to ward off the long-term effects of weightlessness, but many still suffer bone loss, muscle atrophy, and issues with balance and their cardiovascular systems.

3 Jul 2015

Research News and Research

Umeå University researchers capture and describe 'invisible' protein structure

Researchers receive 2.6 million euros to study evolution of sexual reproduction in plants

Study: New test may help predict effectiveness of biologic drugs in RA patients

Two new studies show that fecal transplantation may help fight against ulcerative colitis

Researchers compare effectiveness of two stem cell types in treating retinal degeneration

Gene therapy improves lung function in patients with cystic fibrosis

Phase IIIb CONSIGN study confirms benefit of regorafenib in patients with pre-treated mCRC

Imaging proteasome complex helps show target site for potential cancer drugs

GPS devices help dementia sufferers achieve increased sense of security, quality of life

Increased food energy supply contributes to global obesity epidemic, shows study

Scientists find way to create therapeutic heat to treat people suffering from chronic muscle pain

Gene therapy for cystic fibrosis shows significant benefit in lung function

Creating more effective vaccines against flu virus

Study: Genes may not trigger heart disease in people suffering from migraine with aura

Penn study suggests future precision medicine approach to treating diabetes, other metabolic disorders

Research shows how prion-like proteins critical for maintaining long-term memories

Research finding could lead to first effective therapies, vaccines against dengue virus

NDSU's Stephen O'Rourke awarded NIH grant to conduct cardiovascular research

Review article provides in depth survey of studies focusing on retinoblastoma protein's role in apoptosis

Combination of exercise and artificial gravity may reduce effects of extended weightlessness in space

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