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Potential new class of drugs lessen neurodegeneration in rat model of Parkinson's disease

The first test in a mammalian model of a potential new class of drugs to treat Parkinson's disease shows abatement of neurodegeneration in the brains of test rats and no significant toxicities, University of Alabama at Birmingham and Pfizer Inc. researchers report online in The Journal of Biological Chemistry.

26 Jun 2015

Lamont R Jones receives 2015 Research Scholar Award to study pathogenesis of keloids

Lamont R Jones, M.D., vice chair of the Department of Otolaryngology-Head & Neck Surgery at Henry Ford Hospital, received the 2015 Research Scholar Award from the Educational and Research Foundation for the American Academy of Facial Plastic and Reconstructive Surgery to continue his efforts to study the pathogenesis of keloids and improve understanding of how keloid scars develop.

26 Jun 2015

Bayer Yakuhin receives MHLW approval in Japan for EYLEA (aflibercept) Injection to treat RVO patients

Regeneron Pharmaceuticals, Inc. today announced that Bayer HealthCare's Japanese subsidiary, Bayer Yakuhin, Ltd., received approval for EYLEA (aflibercept) Injection by the Ministry of Health, Labour and Welfare (MHLW) in Japan for the treatment of patients with macular edema secondary to retinal vein occlusion (RVO).

26 Jun 2015

MSD announces EC approval of SIMPONI (golimumab) for treatment of adult patients with nr-axial SpA

MSD (Merck & Co., Inc., Kenilworth, New Jersey, USA) today announced that on 22 June the European Commission approved SIMPONI (golimumab) for the treatment of adult patients with severe, active non-radiographic axial spondyloarthritis (nr-axial SpA).

26 Jun 2015

New UCLA study may lead to more precise treatments for obsessive-compulsive disorder

Tens of millions of Americans -- an estimated 1 to 2 percent of the population -- will suffer at some point in their lifetimes from obsessive-compulsive disorder, a disorder characterized by recurrent, intrusive, and disturbing thoughts (obsessions), and/or stereotyped recurrent behaviors (compulsions).

26 Jun 2015

Diet, acidity of urine may influence susceptibility to urinary tract infections

The acidity of urine -- as well as the presence of small molecules related to diet -- may influence how well bacteria can grow in the urinary tract, a new study shows. The research, at Washington University School of Medicine in St. Louis, may have implications for treating urinary tract infections, which are among the most common bacterial infections worldwide.

26 Jun 2015

Chronic disease, mental health issues affect low-income African-Americans, Latinos and Hispanics

Chronic disease and mental health issues disproportionately affect low-income African-Americans, Latinos and Hispanics, according to the Centers for Disease Control and Prevention. Two new studies by the UCLA Center for Culture, Trauma and Mental Health Disparities shed light on the causes and impacts of this disparity.

26 Jun 2015

UC Santa Barbara professor develops novel therapeutic strategy for PKD

For the 12 million people worldwide who suffer from polycystic kidney disease (PKD), an inherited disorder with no known cure, a new treatment option may be on the horizon.

26 Jun 2015

Caltech chemists develop new sensitive technique that can detect colorectal cancer in tissue samples

Chemists at Caltech have developed a new sensitive technique capable of detecting colorectal cancer in tissue samples -- a method that could one day be used in clinical settings for the early diagnosis of colorectal cancer.

26 Jun 2015

New Internet tool may help analyze genes based on their evolutionary profile

Two major revolutions, one genomic and one in informatics, are completely changing the face of biomedical research. Every day all over the world, millions of genetic sequences -- from disease-related genes to complete genomes of plants, animals, bacteria and viruses -- are resolved, identified and dissected.

26 Jun 2015

UAlberta scientists explore physical principles underlying formation of misfolded protein aggregates

Working towards the ultimate goal to develop therapeutics to treat diseases such as Alzheimer's, Parkinson's, ALS, and BSE (Mad Cow Disease), University of Alberta scientists Michael Woodside, Hao Yu, and Derek Dee are investigating the physical principles underlying the formation of misfolded protein aggregates.

26 Jun 2015

Growth of lymph node metastases takes advantage of existing blood vessels

While the use of antiangiogenesis drugs that block the growth of new blood vessels can improve the treatment of some cancers, clinical trials of their ability to prevent the development of new metastases have failed. Now a study from the Massachusetts General Hospital Cancer Center may have found at least one reason why.

26 Jun 2015

Malaria parasite protein essential for parasite invasion into red blood cells

A new study led by researchers at Harvard T.H. Chan School of Public Health finds that a malaria parasite protein called calcineurin is essential for parasite invasion into red blood cells. Human calcineurin is already a proven target for drugs treating other illnesses including adult rheumatoid arthritis and lupus, and the new findings suggest that parasite calcineurin should be a focus for the development of new antimalarial drugs.

26 Jun 2015

New study reveals key part of Ebola virus life cycle at higher resolution than ever before

A new study led by scientists at The Scripps Research Institute (TSRI) reveals a key part of the Ebola virus life cycle at a higher resolution than ever before. The research sheds light on how Ebola virus assembles—and how researchers might stop the often-fatal infection.

26 Jun 2015

Innovations in AIDS efforts should be leveraged to meet future global health challenges, says UNAIDS-Lancet Commission

Countries most affected by HIV must focus on stopping new HIV infections and expanding access to antiretroviral treatment or risk the epidemic rebounding, urges a major new report from the UNAIDS and Lancet Commission.

26 Jun 2015

IU researchers find that microRNA-29 may be potent therapeutic target against pancreatic cancer

Indiana University cancer researchers found that a particular microRNA may be a potent therapeutic agent against pancreatic cancer. The research was published June 22 in the journal Scientific Reports.

26 Jun 2015

New chemical compound reduces pancreatic cancer tumour growth by 80% in mice

Scientists from UCL (University College London) have designed a chemical compound that has reduced the growth of pancreatic cancer tumours by 80 percent in treated mice.

26 Jun 2015

Light may just be the answer for solving sleep problems among lung cancer patients

When you're having trouble sleeping, light is the last thing you assume you need. But according to a pilot study attempting to solve insomnia among lung cancer patients led by University at Buffalo sleep researcher Grace Dean, light may just be the answer.

26 Jun 2015

Lund University research questions the doctrine on how the brain recognizes and processes information

New research from Lund University in Sweden questions the prevailing doctrine on how the brain absorbs and processes information. The idea that the brain has a mechanism to maintain activity at the lowest possible level is incorrect.

26 Jun 2015

Fructose stimulates reward system in the brain to a lesser degree than glucose

Fructose not only results in a lower level of satiety, it also stimulates the reward system in the brain to a lesser degree than glucose. This may cause excessive consumption accompanied by effects that are a risk to health, report researchers from the University of Basel in a study published in the scientific journal PLOS ONE. Various diseases have been attributed to industrial fructose in sugary drinks and ready meals.

26 Jun 2015

Research News and Research

Potential new class of drugs lessen neurodegeneration in rat model of Parkinson's disease

Lamont R Jones receives 2015 Research Scholar Award to study pathogenesis of keloids

Bayer Yakuhin receives MHLW approval in Japan for EYLEA (aflibercept) Injection to treat RVO patients

MSD announces EC approval of SIMPONI (golimumab) for treatment of adult patients with nr-axial SpA

New UCLA study may lead to more precise treatments for obsessive-compulsive disorder

Diet, acidity of urine may influence susceptibility to urinary tract infections

Chronic disease, mental health issues affect low-income African-Americans, Latinos and Hispanics

UC Santa Barbara professor develops novel therapeutic strategy for PKD

Caltech chemists develop new sensitive technique that can detect colorectal cancer in tissue samples

New Internet tool may help analyze genes based on their evolutionary profile

UAlberta scientists explore physical principles underlying formation of misfolded protein aggregates

Growth of lymph node metastases takes advantage of existing blood vessels

Malaria parasite protein essential for parasite invasion into red blood cells

New study reveals key part of Ebola virus life cycle at higher resolution than ever before

Innovations in AIDS efforts should be leveraged to meet future global health challenges, says UNAIDS-Lancet Commission

IU researchers find that microRNA-29 may be potent therapeutic target against pancreatic cancer

New chemical compound reduces pancreatic cancer tumour growth by 80% in mice

Light may just be the answer for solving sleep problems among lung cancer patients

Lund University research questions the doctrine on how the brain recognizes and processes information

Fructose stimulates reward system in the brain to a lesser degree than glucose

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