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Discovery of protein function could be important for future chemotherapy treatment

Chemotherapy attacks all cells in our body and not just cancer cells, which is why patients undergoing the treatment often experience side effects such as physical weakness, hair loss and nausea.

17 Dec 2020

Supercomputer simulations lead to an important viral inhibitor discovery

University of New Hampshire researchers recently used Comet at the San Diego Supercomputer Center at UC San Diego and Stampede2 at the Texas Advanced Computing Center to identify new inhibitor binding/unbinding pathways in an RNA-based virus.

17 Dec 2020

Study highlights how the sex differences in COVID-19 are linked to ACE2 protein

Female COVID-19 patients face less severe disease complications and a lower risk of dying than male patients thanks to hormones and chromosomes that contribute to a stronger immune response, according to new research from a University of Alberta-led team.

17 Dec 2020

Errant DNA triggers immune system response against cancer

DNA that ends up where it doesn't belong in cancer cells can unleash an immune response that makes tumors more susceptible to immunotherapy, the results of two UT Southwestern studies indicate.

17 Dec 2020

Researchers discover cells responsible for resistance to T-ALL treatment

T-cell acute lymphoblastic leukemia (T-ALL) is a cancer of the blood that affects mainly children, but also less frequently adults. In adults, although the response to treatment might be initially positive, relapses are common and have a poor prognosis.

17 Dec 2020

Gene surfing caused the SARS-CoV-2 D614G variant to rise to dominance in the US

A recent preprint that appeared on the bioRxiv* server applies a new approach to conventional birth-death lineage modeling.

17 Dec 2020

Hepatitis C virus drugs synergize with remdesivir against SARS-CoV-2 in vitro

SARS-CoV-2 has infected over 71.5 million people and claimed over 1.6 million lives globally since December 2019.

17 Dec 2020

Researchers find evidence that COVID-19 spread is sensitive to UV exposure

Scientists, policymakers and healthcare workers are eager to discern to what extent COVID-19 may be seasonal. Understanding this aspect of the disease could guide our response to the pandemic.

17 Dec 2020

FAT1 mutations act as tumor suppressor and prevent cancer development, indicates study

Cancer metastasis, which is the dissemination of tumor cells into distant organs, is the leading cause of mortality in cancer patients. To undergo metastasis, cells must leave the primary tumor, circulate into the blood, colonize distant organs, and form distant metastasis.

17 Dec 2020

Specific genetic target could help explain the variation in COVID-19 effects

The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become.

17 Dec 2020

Study shows how melanomas assist T cells from identifying and killing tumor cells

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

17 Dec 2020

4E-BP proteins are key to unlock the antidepressant effect of ketamine in the brain

A group of proteins called 4E-BPs, involved in memory formation, is the key to unlocking the antidepressant effect of ketamine in the brain, according to researchers from three Canadian universities. The discovery could lead to better and safer treatments for certain patients suffering from major depression.

17 Dec 2020

Researchers identify neurons that regulate nausea-like responses in mice

At some point, everyone experiences nausea. Whether it occurs after unwisely eating a week-old slice of pizza or as an accompaniment to a serious infection, that queasy, unsettling sensation centered around the stomach is a signal that something is amiss within the body and typically portends a bout of vomiting.

17 Dec 2020

Genetic News and Research

Discovery of protein function could be important for future chemotherapy treatment

Supercomputer simulations lead to an important viral inhibitor discovery

Study highlights how the sex differences in COVID-19 are linked to ACE2 protein

Errant DNA triggers immune system response against cancer

Researchers discover cells responsible for resistance to T-ALL treatment

Gene surfing caused the SARS-CoV-2 D614G variant to rise to dominance in the US

Hepatitis C virus drugs synergize with remdesivir against SARS-CoV-2 in vitro

Researchers find evidence that COVID-19 spread is sensitive to UV exposure

FAT1 mutations act as tumor suppressor and prevent cancer development, indicates study

Specific genetic target could help explain the variation in COVID-19 effects

Study shows how melanomas assist T cells from identifying and killing tumor cells

4E-BP proteins are key to unlock the antidepressant effect of ketamine in the brain

Researchers identify neurons that regulate nausea-like responses in mice

Researchers explain the role of enzyme that facilitates appropriate development of mouse embryo

Researchers examine proteins involved in SARS-CoV-2 infection

Brain protein indicates a link between circadian rhythm dysfunction and Alzheimer's Disease

Expanded biodiversity infrastructure is essential for pandemic preparedness, say experts

A new approach to identify genomic regions in our brain that contribute to make us human

$3.7 million NIH grant supports development of biosensor technology for diagnosing viral diseases

Autoimmune condition biomarkers promote SARS-CoV-2 viral entry, study finds

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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